Kirjahaku

Solid dosage forms like tablet and capsule are most popular and preferred drug delivery system because they have high patient compliance, relatively easy to produce, easy to market, accurate dosing, and good physical and chemical stability. Many patient find difficulty to swallow tablet and hard gelatin capsule, consequently they do not take medication as prescribed results high incident of incompliance and ineffective therapy.

A drug includes all medicines intended for internal or external use for or in the diagnosis, treatment, mitigation or prevention of disease or disorder in human beings or animals, and manufactured exclusively in accordance with the formulae mentioned in authoritative books.

Mucilages are generally normal product of metabolism formed within the cell (intra cellular formation ) or are produced without injury to the plant .mucilages are normaly physiological products .they are often found different part of the plants, for example in the epidermal cell of leaves (senna), seed coats (linseed), roots (marshmallow), barks(slippery elm) and middle lamella (aloe).Mucilages have certain plants hydrocolloid the are translucent amorphous substances and polymers of monosaccharide or mixed monosaccharide and many of them combined with uronic acids. Mucilages and gums have similar constituents and on hydrolysis yield mixture of sugars and uronic acids.Mucilages certain hydrophilic molecules, which can combine with water to forms viscous solutions or gels.

Combinatorial chemistry is a new methodology by which we can simultaneously synthesize a number of possible compounds that could produce simultaneously a very large number of compounds, called libraries. Combinatorial chemistry involves the rapid synthesis or the computer simulation of a large number of different but often structurally related molecules or materials. Combinatorial chemistry is especially common in CADD (Computer aided drug design) and can be done online with web based software, such as Molinspiration.