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4 kirjaa tekijältä Andrew Blann

Data Handling and Analysis

Data Handling and Analysis

Andrew Blann

Oxford University Press
2018
nidottu
Biomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible. The Fundamentals of Biomedical Science series has been written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis. Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science. Data Handling and Analysis is the most relevant and useful statistics and data analysis text for biomedical science students. Providing a broad review of the quantitative skills needed to be an effective biomedical scientist, the text spans the collection, presentation, and analysis of data. It draws on relevant examples throughout, creating an ideal introduction to the subject for any student of biomedical science.
Biology of Disease

Biology of Disease

Andrew Blann

Oxford University Press
2024
nidottu
The Fundamentals of Biomedical Science series has been written to reflect the challenges of practising biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis. Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a biomedical scientist may be exposed - from microbiology to cytopathology to transfusion science. Biology of Disease provides an integrated introduction to the basic cell biology that underlies disease processes and the diagnosis and management of those diseases. By telling the whole story of how a disease develops, how it is diagnosed, and how it is treated, the text provides a thorough understanding of both the molecular and clinical aspects of diseases that are needed to succeed as a practising health care professional. Featuring a wide range of diseases, the text places particular emphasis on diseases that biomedical scientists and other health care professionals are most likely to encounter in a clinical setting and that have the greatest impact on people's lives. This is reflected in the book's detailed coverage of cancer and cardiovascular disease, which have long been causing many deaths each year, and its discussion of the COVID-19 pandemic. The inclusion of clinical case studies throughout shows how the theory of disease processes informs the diagnosis and treatment of different diseases in practice. Self-check questions and discussion questions in the book support active learning and allow students to check their understanding. Multiple-choice questions are embedded into the e-book and Science Trove, allowing students to recap seamlessly on what they have learnt in each chapter. Digital formats and resources Biology of Disease is available for students and institutions to purchase in a variety of formats. - The e-book offers a mobile experience and convenient access along with functionality tools, navigation features, and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks - E-book and Science Trove products are enriched with digital multiple-choice questions and answers to the self-check questions - Instructor resources include figures from the book, available to download
Molecular Pathology

Molecular Pathology

Andrew Blann

JOHN WILEY SONS INC
2025
nidottu
Comprehensive textbook on molecular pathology for newcomers to the field, covering history, analytics, types of cancers, and more Molecular Pathology delivers an in-depth outline of molecular pathology appropriate for the undergraduate, postgraduate, or early-stage career lab scientist, drawing from authoritative sources such as NICE, the World Health Organisation, the Office of National Statistics, clinical guidelines, research publications and the National Genomic Test Directory. The text contains numerous tables, diagrams, and photos in each chapter to help elucidate key concepts. The opening chapter provides a general introduction to the subject with a historical perspective of key findings that have led to our current view of molecular pathology. The introduction is followed by a look at the scope of chromosomal disease (such as Down’s syndrome) and genetic disease (such as sickle cell disease). Chapter two describes the numerous analytical tools required in molecular pathology, and how complex genetic data is interpreted – i.e., bioinformatics. The remaining three chapters review the molecular pathology of focused groups of disease, including solid tumor cancer, blood cancer, and metabolic and other genetic diseases. Each of these three chapters explains the role of molecular pathology in the etiology, diagnosis, and management of each particular condition. Sample topics explored in Molecular Pathology include: Generating DNA and RNA for analysis, amplification by PCR, and DNA sequencing through micro-arrays, libraries, and Next Generation SequencingChromosome structure, covering histones and the centromere, abnormal chromosome numbers, and errors within chromosomes such as translocations and deletionsMyelofibrosis, myelodysplasia, essential thrombocythemia, polycythaemia, leukemia, lymphoma, myeloma, and haemopoiesis and maturation arrestMolecular pathology of single organ/organ system disease, such as Huntington’s and cardiomyopathy, and multi-organ disease such as Barth syndrome Molecular Pathology serves as an excellent introduction to the subject for first to third year undergraduate students. Healthcare professionals and biomedical scientists and researchers will also find it valuable.