In 1503, for the first time, a student in Paris was able to spend his entire university career studying only the printed textbooks of his teacher, thanks to the works of the humanist and university reformer Jacques Lefèvre d'Étaples (c. 1455-1536). As printed books became central to the intellectual habits of following generations, Lefèvre turned especially to mathematics as a way to renovate the medieval university. Making Mathematical Culture argues this was a pivatol moment in the cultural history of Europe and explores how the rise of the printed book contributed to the growing profile of mathematics in the region. Using student manuscripts and annotated books, Making Mathematical Culture offers a new account of printed textbooks, as jointly made by masters and students, and how such collaborative practices informed approaches to mathematics.