Kirjahaku

The crucial role of animal models in biomedical research calls for philosophical investigation of how and whether knowledge about human diseases can be gained by studying other species. This Element delves into the selection and construction of animal models to serve as preclinical substitutes for human patients. It explores the multifaceted roles animal models fulfil in translational research and how the boundaries between humans and animals are negotiated in this process. The book also covers persistent translational challenges that have sparked debates across scientific, philosophical, and public arenas regarding the limitations and future of animal models. Among the are persistent tensions between standardization and variation in medicine, as well as between strategies aiming to reduce and recapitulate biological complexity. Finally, the book examines the prospects of replacing animal models with animal-free methods. The Element demonstrates why animal modeling should be of interest to philosophers, social scientists, and scientists alike.

The crucial role of animal models in biomedical research calls for philosophical investigation of how and whether knowledge about human diseases can be gained by studying other species. This Element delves into the selection and construction of animal models to serve as preclinical substitutes for human patients. It explores the multifaceted roles animal models fulfil in translational research and how the boundaries between humans and animals are negotiated in this process. The book also covers persistent translational challenges that have sparked debates across scientific, philosophical, and public arenas regarding the limitations and future of animal models. Among the are persistent tensions between standardization and variation in medicine, as well as between strategies aiming to reduce and recapitulate biological complexity. Finally, the book examines the prospects of replacing animal models with animal-free methods. The Element demonstrates why animal modeling should be of interest to philosophers, social scientists, and scientists alike.

Disney has made magic for kids everywhere. Since 1923, it has introduced beloved characters such as Mickey Mouse and Olaf the Snowman. Disney has also created whole worlds for children to visit across the globe with its theme parks. Curious readers will be spellbound as they learn about this enchanting company.

The name "LEGO" comes from the Danish phrase for “play well.” The company’s popular toys have helped children to do just that. This title for inventive readers explores how a Danish family built up their small business brick by brick to create the world’s third-largest toy company.

Did somebody say McDonald’s? From its humble beginnings as a barbeque restaurant, McDonald’s has established itself as a global giant with more than 35,000 restaurants worldwide. Find out more about how the iconic hamburger chain got its start in this title for young readers.

Though Apple was founded on April Fools’ Day, this company doesn’t kid around. From the start, Apple has delivered top-notch technology, including the iPod, iPad, MacBook Pro, and more. This title explores the tech-savvy side in all its inventive readers.

Google’s name today, originally “googol,” was a spelling mistake, but the company’s worldwide success is no error. Through the development of Google’s search engine and other online tools, founders Sergey Brin and Larry Page have come a long way since their time at Stanford University. Explore more about Google’s founders and innovations in this title for growing readers.

Plows in the 1830s were not suitable for sticky sod, so John Deere invented a smooth, steel plow that worked for many farmers. He continued to press on by creating his own company and building a brand that is well-known today. In this title, young readers can discover more about this inspiring innovator and his company.

Nearly fifty years ago, Reyn Guyer created the original Nerf ball. The lightweight toy appealed to many because it couldn't cause any damage! Since then, Nerf has blasted its way to becoming one of Hasbro’s top brands. Learn more about the evolution of Nerf in this fun book for active minds.

Minecraft players have free reign of the spaces they build in, but they better stay alert during the night! Designed by Markus Persson, Minecraft has sold over 20 million computer games since 2009! Minecraft is the epitome of imagination and creativity. In this title for exploring minds, learn more about the making of Minecraft and how this game became a hit sensation.

Netflix has played a role in making binge-watching a thing. Seventy percent of its users watch television series episode after episode after episode in one sitting! This children’s book rewinds Netflix back to its beginning, when the focus was mailing DVDs, and then expands upon the company’s growth over a decade.

Pikachu could be called the mascots of the Pokémon brand, as the short, yellow furballs are the most recognizable of hundreds of characters. This book for growing readers tracks the birth of the Japanese pocket monsters chased all around cities by Pokémon Go players.

Every saga has a beginning. This marketing tagline for Star Wars: Episode I— The Phantom Menace could also be the tagline for this biography of the Stars Wars brand. Young readers will travel back to a long time ago in a galaxy far, far away…

Since Hello Kitty first appeared on a coin purse in 1974, Sanrio has grown the brand into a worldwide phenomenon The famous white cat character has made a name for herself by appearing on everything from pencils to airplanes. This title explores Hello Kitty's rise to fame and what we can expect from the brand in the future.

Did you know that the Labrador retriever that starred in Marley and Me was a rescue dog from a shelter in Florida? His is a true rags-to-riches story! This title explores the history of animals in entertainment while highlighting some of the pet pals we have grown to love on the silver screen!

Is it a space adventure or slit scan? The camera technique slit scan has been used to create the illusion of flying through space in movies like 2001 A Space Odyssey. Young readers will read about the camera tricks and special equipment used to create the jaw-dropping effects of motion pictures in Camera Tricks.

Costumes and props fill the sets of films! From tiny, frozen blueberries in The Hunger Games to a 108-pound gown in the 1938 film Marie Antoinette, they take on many shapes and sizes. Today, some are even created through 3D printing! This title weaves through the costumes and props of our favorite films while captivating readers with relevant photos and riveting film facts.

During the filming of the Harry Potter series, Harry Potter’s scar was painted on 5,800 times! About 2,000 of those were painted on Daniel Radcliffe who played Harry Potter. This title explores the makeup, tools, and effects used to create everything from the scariest of monsters to the most elegant ladies.

The action of the big screen--car crashes, torrential rainfall, ships sinking--is the work of special effects! Directors and crews use anything they can to create a real and captivating experience. Enormous models, airplane engines, controlled fires, and much more create the excitement we all crave! Young readers will marvel over this behind-the-scenes look at how movies are made.