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Oral Bioavailability and Drug Delivery

Oral Bioavailability and Drug Delivery

JOHN WILEY SONS INC
2024
sidottu
ORAL BIOAVAILABILITY AND DRUG DELIVERY Improve the performance and viability of newly-developed and approved drugs with this crucial guide Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user’s circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability are therefore critical aspects of drug development. Oral Bioavailability and Drug Delivery provides a comprehensive coverage of this subject as well as its drug development applications. Beginning with basic terminology and fundamental concepts, it provides a thorough understanding of the challenges and barriers to oral bioavailability as well as the possibilities for improving this parameter. The resulting book is an indispensable tool for drug development research. Oral Bioavailability and Drug Delivery readers will also find: Discussion questions in many chapters to facilitate comprehensionDetailed discussion of topics including dissolution, absorption, metabolism, and moreReal-world examples of methods in actions throughout Oral Bioavailability and Drug Delivery is ideal for pharmaceutical and biotechnology scientists working in drug discovery and development; researchers in chemistry, biology, pharmacology, immunology, neuroscience, and other related fields; and graduate courses in drug development and delivery.
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Oral Drug Delivery for Modified Release Formulations

Oral Drug Delivery for Modified Release Formulations

Wiley-Blackwell
2022
sidottu
ORAL DRUG DELIVERY FOR MODIFIED RELEASE FORMULATIONS Provides pharmaceutical development scientists with a detailed reference guide for the development of MR formulations Oral Drug Delivery for Modified Release Formulations is an up-to-date review of the key aspects of oral absorption from modified-release (MR) dosage forms. This edited volume provides in-depth coverage of the physiological factors that influence drug release and of the design and evaluation of MR formulations. Divided into three sections, the book begins by describing the gastrointestinal tract (GIT) and detailing the conditions and absorption processes occurring in the GIT that determine a formulation’s oral bioavailability. The second section explores the design of modified release formulations, covering early drug substance testing, the biopharmaceutics classification system, an array of formulation technologies that can be used for MR dosage forms, and more. The final section focuses on in vitro, in silico, and in vivo evaluation and regulatory considerations for MR formulations. Topics include biorelevant dissolution testing, preclinical evaluation, and physiologically-based pharmacokinetic modelling (PBPK) of in vivo behaviour. Featuring contributions from leading researchers with expertise in the different aspects of MR formulations, this volume: Provides authoritative coverage of physiology, physicochemical determinants, and in-vitro in-vivo correlation (IVIVC)Explains the different types of MR formulations and defines the key terms used in the fieldDiscusses the present status of MR technologies and identifies current gaps in researchIncludes a summary of regulatory guidelines from both the US and the EUShares industrial experiences and perspectives on the evaluation of MR dosage formulations Oral Drug Delivery for Modified Release Formulations is an invaluable reference and guide for researchers, industrial scientists, and graduate students in general areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.
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Oral and Maxillofacial Surgery

Oral and Maxillofacial Surgery

JOHN WILEY SONS INC
2025
sidottu
Detailed reference on the full scope of oral and maxillofacial surgery for dentists and surgeons Oral and Maxillofacial Surgery, Second Edition is a comprehensive reference to oral and maxillofacial surgery. Suitable for fields of dentistry, surgery, and medicine that treat conditions of the head and neck, this resource draws together current research, practice, and developments to create a detailed guide for both practicing surgeons and trainees. From pre-operative through to post-operative management, this book’s coverage extends from basic principles such patient evaluation, dental anesthesia, wound healing, infection control, and surgical instrument through to the complex areas of dentoalveolar surgery, oral pathologic lesions, trauma, implant surgery, dentofacial deformities, temporomandibular joint disorders, and salivary gland disorders. The second edition is fully updated throughout with contributions from international experts offering a global perspective. Readers will find includes new chapters on the innovations affecting the care of surgical patients. These include virtual surgical planning, navigation, and tissue engineering for reconstruction. Pediatric-specific chapters have also been added in trauma and temporomandibular joint surgery, as well as an expanded section on cosmetic surgery. All updates are accompanied by images and medical illustrations reflecting the changes in this specialty area of dental and medical care. Oral and Maxillofacial Surgery also includes information on: State of the art clinical practiceTechnical aspects of minimally invasive cosmetic proceduresDiagnosis and treatment of obstructive sleep apnea, and the role of maxillary and mandibular osteotomiesDiagnostic strategies, risk assessment, and guidelines for staging as well as surgical and non-surgical management of osteonecrosis of the jawsClinical and radiographic characteristics of odontogenic and nonodontogenic cysts of the jaws, with strategies for management The second edition of Oral and Maxillofacial Surgery remains an essential landmark in a transforming field and is suitable for oral and maxillofacial specialists, dental surgeons, OMS residents, and trainees.
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Oral Medicine and Medically Complex Patients

Oral Medicine and Medically Complex Patients

JOHN WILEY SONS INC
2025
sidottu
Leading practical reference on managing in-hospital dental patients and medically complex outpatients with special health care needs Oral Medicine and Medically Complex Patients, Seventh Edition provides succinct yet comprehensive information on in-hospital care and outpatient management of medically complex dental patients, as well as the management of surgical and non-surgical problems of the maxillofacial region. This text follows a practical approach, organizing essential information into quickly referenced tables, easy to read diagrams, and step-by-step procedures. Replete with examples of hospital charting, notes, and consultations, the book provides thorough coverage of a broad scope of clinical problems and patient populations. Oral Medicine and Medically Complex Patients, Seventh Edition features: Up-to-date information on patient examination, assessment, diagnosis, and proceduresAdditional charts and tables, over 100 new color clinical images, expanded coverage on maxillofacial prosthodontics and increasingly prevalent medical and orofacial conditionsAn emphasis on recent research, scientific findings and guidelines from the past decade that inform treatment options and provide a strong evidence base for oral health care Oral Medicine and Medically Complex Patients, Seventh Edition contains essential information for general practice, oral medicine, maxillofacial surgery, and pediatric dentistry residents, dental students, dentists in non-traditional practice settings, and all community-based dental practitioners. This text serves the needs of an increasing number of dental students, residents in general practice and specialty training programs, and a wide spectrum of dental practitioners engaged in the care of both hospitalized and ambulatory patients.
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Oral History and Photography

Oral History and Photography

Palgrave Macmillan
2012
nidottu
This book collects original research essays to explore the diverse uses of photographs and photography in oral history, from the use of photos as memory triggers to their deployment in the telling of life stories. The book's contributors include both oral historians and photography scholars and critics.
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Oral History in Southeast Asia

Oral History in Southeast Asia

Palgrave Macmillan
2013
sidottu
Using the presence of the past as a point of departure, this books explores three critical themes in Southeast Asian oral history: the relationship between oral history and official histories produced by nation-states; the nature of memories of violence; and intersections between oral history, oral tradition, and heritage discourses.
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Oral History and Digital Humanities

Oral History and Digital Humanities

Douglas A. Boyd

Palgrave Macmillan
2014
sidottu
Exploring the developments that have occurred in the practice of oral history since digital audio and video became viable, this book explores various groundbreaking projects in the history of digital oral history, distilling the insights of pioneers in the field and applying them to the constantly changing electronic landscape of today.
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Oral History and Digital Humanities

Oral History and Digital Humanities

Douglas A. Boyd

Palgrave Macmillan
2014
nidottu
Exploring the developments that have occurred in the practice of oral history since digital audio and video became viable, this book explores various groundbreaking projects in the history of digital oral history, distilling the insights of pioneers in the field and applying them to the constantly changing electronic landscape of today.
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Oral History Off the Record

Oral History Off the Record

Palgrave Macmillan
2013
sidottu
Because oral history interviews are personal interactions between human beings, they rarely conform to a methodological ideal. These reflections from oral historians provide honest and rigorous analyses of actual oral history practice that address the complexities of a human-centered methodology.
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Oral History Off the Record

Oral History Off the Record

Palgrave Macmillan
2013
nidottu
Because oral history interviews are personal interactions between human beings, they rarely conform to a methodological ideal. These reflections from oral historians provide honest and rigorous analyses of actual oral history practice that address the complexities of a human-centered methodology.
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Oral Interpretation

Oral Interpretation

Timothy Gura; Benjamin Powell

Routledge
2018
sidottu
In its 13th Edition, the iconic Oral Interpretation continues to prepare students to analyze and perform literature through an accessible, step-by-step process. New selections join classic favorites, and chapters devoted to specific genres—narrative, poetry, group performance, and more—explore the unique challenges of each form. Now tighter and more focused than its predecessors, this edition highlights movements in contemporary culture—especially the contributions of social media to current communication. New writings offer advice and strategies for maximizing body and voice in performance, and enhanced devices guide novices in performance preparation.
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Oral Interpretation

Oral Interpretation

Timothy Gura; Benjamin Powell

Routledge
2018
nidottu
In its 13th Edition, the iconic Oral Interpretation continues to prepare students to analyze and perform literature through an accessible, step-by-step process. New selections join classic favorites, and chapters devoted to specific genres—narrative, poetry, group performance, and more—explore the unique challenges of each form. Now tighter and more focused than its predecessors, this edition highlights movements in contemporary culture—especially the contributions of social media to current communication. New writings offer advice and strategies for maximizing body and voice in performance, and enhanced devices guide novices in performance preparation.
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Oral Traditions and the Verbal Arts

Oral Traditions and the Verbal Arts

Ruth Finnegan

Routledge
2017
sidottu
The study of oral traditions and verbal arts leads into an area of human culture to which anthropologists are increasingly turning their attention. Oral Traditions and the Verbal Arts provides up-to-date guidance on how to approach the study of oral form and their performances, treating both the practicalities of fieldwork and the methods by which oral texts and performances can be observed, collected or analysed. It also relates to those current controversies about the nature of performance and of 'text'.Designed as a practical and systematic introduction to the processes and problems of researching in this area, this is an invaluable guide for students, and lecturers of anthropology and cultural studies and also for general readers who are interested in enjoying oral literature for its own sake.
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Oral Medicine

Oral Medicine

Michael Lewis; Richard Jordan

CRC Press
2018
nidottu
This is a revised edition of a bestselling handbook. The authors have fully updated the text to include the most up to date treatment options, have added a section on head and neck imaging (CT/MRI), a series of self-test clinical cases, and 100 new photographs. The book uses a symptom-based approach to assist the clinician in the diagnosis and management of those conditions that fall into the speciality of oral medicine. Dealing first with normal anatomy, physical examination and investigation—particularly lesional biopsy, hematological assessment and microbiological sampling—the authors cover all areas of those diseases, local and systemic, that manifest themselves in the lips and mouth. Conditions are grouped under their principal presenting sign—blistering, white patches, red patches, swelling, pigmentation, pain, dry mouth, altered taste, and halitosis. This comprehensive handbook is of value to professionals and trainees in medicine, dentistry and pathology.
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Oral Tradition

Oral Tradition

Jan Vansina

Routledge
2017
sidottu
Oral traditions are historical sources of a special nature. Their special nature derives from the fact that they are "unwritten" sources couched in a form suitable for oral transmission, and that their preservation depends on the powers of memory of successive generations of human beings. In many parts of the world inhabited by peoples without writing, oral tradition forms the main available source for a reconstruction of the past. Do the special characteristics of oral traditions u "unwritten" information dependent on the memory of successive generations u invalidate them as sources of historical data? If not, are there means for testing their reliability? Professor Vansina shows in Oral Tradition that with knowledge of the language and of the society, the anthropologist and historian can extract or deduce the historical content of oral testimonies. Based on the author's many years of fieldwork in Africa, this definitive work explores the possibility of reconstructing the history of non-literate peoples from their oral traditions, surveys existing literature, offers a typology of oral traditions, and evaluates methods of collection and interpretation. On first publication, Daniel McCall in the American Anthropologist called Oral Tradition " a tour de force. Indeed this may well be the most significant work written on the relation of oral tradition to history in thirty yearsafor any field worker who intends to collect oral traditions, this work is indispensable."
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Oral Traditions and Gender in Early Modern Literary Texts

Oral Traditions and Gender in Early Modern Literary Texts

Mary Ellen Lamb; Karen Bamford

Routledge
2020
nidottu
Proposing a fresh approach to scholarship on the topic, this volume explores the cultural meanings, especially the gendered meanings, of material associated with oral traditions. The collection is divided into three sections. Part One investigates the evocations of the 'old nurse' as storyteller so prominent in early modern fictions. The essays in Part Two investigate women's fashioning of oral traditions to serve their own purposes. The third section disturbs the exclusive associations between the feminine and oral traditions to discover implications for masculinity, as well. Contributors explore the plays of Shakespeare and writings of Spenser, Sidney, Wroth and the Cavendishes, as well as works by less well known or even unknown authors. Framed by an introduction by Mary Ellen Lamb and an afterword by Pamela Allen Brown, these essays make several important interventions in scholarship in the field. They demonstrate the continuing cultural importance of an oral tradition of tales and ballads, even if sometimes circulated in manuscript and printed forms. Rather than in its mode of transmission, contributors posit that the continuing significance of this oral tradition lies instead in the mode of consumption (the immediacy of the interaction of the participants). Oral Traditions and Gender in Early Modern Literary Texts confirms the power of oral traditions to shape and also to unsettle concepts of the masculine as well as of the feminine. This collection usefully complicates any easy assumptions about associations of oral traditions with gender.
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Oral History

Oral History

Routledge
2017
muu
The rapid rise in the study of Oral History has been evident across a wide range of academic and community settings. From surgeons in England investigating the embodied memories of half-remembered techniques in no longer practiced operations, to truth and reconciliation projects in countries recovering from civil conflict, including in South Africa, Oral History is as diverse and widespread in practice as it is in application. This four-volume collection of cutting edge and canonical research will be of interest to students and scholars alike.
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Oral History, Health and Welfare

Oral History, Health and Welfare

Routledge
2014
nidottu
Oral History, Health and Welfare discusses the significance of oral history to the history of the development of health and welfare provisions. It includes discussion on:* the end of the workhouse * professional education and training of midwives * HIV and Aids * birth control * the role of the community pharmacist * pioneers of geriatric medicine * oral history and the history of learning disability.
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