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1000 tulosta hakusanalla C. David Heymann

David Crockett

David Crockett

John S C Abbott

Hansebooks
2017
pokkari
David Crockett - His Life and Adventures is an unchanged, high-quality reprint of the original edition of 1874. Hansebooks is editor of the literature on different topic areas such as research and science, travel and expeditions, cooking and nutrition, medicine, and other genres. As a publisher we focus on the preservation of historical literature. Many works of historical writers and scientists are available today as antiques only. Hansebooks newly publishes these books and contributes to the preservation of literature which has become rare and historical knowledge for the future.
David Crockett

David Crockett

John S C Abbott

Anatiposi Verlag
2023
pokkari
Reprint of the original, first published in 1875. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
David Crockett

David Crockett

John S C Abbott

Anatiposi Verlag
2023
sidottu
Reprint of the original, first published in 1875. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
Epigenetic Effects of Vitamin C on the Diabetic Retina

Epigenetic Effects of Vitamin C on the Diabetic Retina

David Sant

LAP Lambert Academic Publishing
2019
pokkari
The work presented here includes an investigation of the relationship between hyperglycemia-induced local vitamin C deficiency in the eyes of diabetics and diabetic eye complications through epigenetics. Methylcytosine (5mC) and hydroxymethylcytosine (5hmC) are the main covalent modifications of deoxyribonucleic acid (DNA) and are maintained by DNA methyltransferases (DNMT) and Ten-Eleven-Translocation (TET) enzymes. Vitamin C acts as a cofactor for the TET enzymes and when a deficiency presents it results in a disruption of the methylation/demethylation dynamics. In this work, retinal cells are cultured either in a deficiency or sufficiency of vitamin C and the hydroxymethylome and transcriptome are investigated. The most interesting finding is that a deficiency of vitamin C leads to an overproduction of vascular endothelial growth factor (VEGF), which has long been implicated in diabetic eye complications. This suggests that a correction of the local vitamin C deficiency could prevent or possibly even ameliorate symptoms of diabetic retinopathy.
The Rhetorical Use of Numbers in the Deuteronomistic History: "Saul Has Killed His Thousands, David His Tens of Thousands"
The Deuteronomistic History contains many vast troop and casualty numbers. What purpose does this literary device of numerical hyperbole serve? What rhetorical purposes do any of the numbers in this text serve? In The Rhetorical Use of Numbers in the Deuteronomistic History: "Saul Has Killed His Thousands, David His Tens of Thousands," Denise Flanders explores the variety of rhetorical effects that numbers have on the narrative of Joshua-2 Kings. Flanders demonstrates that numbers in Joshua-2 Kings often work in surprising and subversive ways. Rather than regularly glorifying a leader, large casualty numbers may actually anticipate a ruler's downfall. Rather than underscoring an Israelite battle victory, numbers sometimes qualify or undermine the triumph of victories.