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The Human Genome in Health and Disease

The Human Genome in Health and Disease

Tore Samuelsson

CRC Press
2019
sidottu
The human genome is a linear sequence of roughly 3 billion bases and information regarding this genome is accumulating at an astonishing rate. Inspired by these advances, The Human Genome in Health and Disease: A Story of Four Letters explores the intimate link between sequence information and biological function. A range of sequence-based functional units of the genome are discussed and illustrated with inherited disorders and cancer. In addition, the book considers valuable medical applications related to human genome sequencing, such as gene therapy methods and the identification of causative mutations in rare genetic disorders.The primary audiences of the book are students of genetics, biology, medicine, molecular biology and bioinformatics. Richly illustrated with review questions provided for each chapter, the book helps students without previous studies of genetics and molecular biology. It may also be of benefit for advanced non-academics, which in the era of personal genomics, want to learn more about their genome.Key selling features:Molecular sequence perspective, explaining the relationship between DNA sequence motifs and biological functionAids in understanding the functional impact of mutations and genetic variantsMaterial presented at basic level, making it accessible to students without previous studies of genetics and molecular biologyRichly illustrated with questions provided to each chapter
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The Affective Negotiation of Slum Tourism

The Affective Negotiation of Slum Tourism

Tore Holst

Routledge
2020
nidottu
Each year, approximately a million tourists visit slum areas on guided tours as a part of their holiday to Asia, Africa or Latin America. This book analyses the cultural encounters that take place between slum tourists and former street children, who work as tour guides for a local NGO in Delhi, India. Slum tours are typically framed as both tourist performances, bought as commodities for a price on the market, and as appeals for aid that tourists encounter within an altruistic discourse of charity. This book enriches the tourism debate by interpreting tourist performances as affective economies, identifying tour guides as emotional labourers and raising questions on the long-term impacts of economically unbalanced encounters with representatives of the Global North, including the researcher.This book studies the ‘feeling rules’ governing a slum tour and how they shape interactions. When do guides permit tourists to exoticise the slum and feel a thrilling sense of disgust towards the effects of abject poverty, and when do they instead guide them towards a sense of solidarity with the slum’s inhabitants? What happens if the tourists rebel and transgress the boundaries delimiting the space of comfortable affective negotiation constituted by the guides? This book will be essential reading for undergraduates, postgraduates and researchers working within the fields of Human Geography, Slum Tourism Research, Subaltern Studies and Development Studies.
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Reviving Critical Planning Theory

Reviving Critical Planning Theory

Tore Øivin Sager

Routledge
2012
sidottu
Discussing some of the most vexing criticism of communicative planning theory (CPT), this book goes on to suggest how theorists and planners can respond to it. Looking at issues of power, politics and ethics in relation to planning, this book is for both critics and advocates of CPT, with lessons for all. With severe criticisms being raised against CPT, the need has arisen to systematically think through what responsibilities planning theorists might have for the end-uses of their theoretical work. Offering inventive proposals for amending the shortcomings of this widely adhered planning method, this book reflects on what communicative planning theorists and practitioners can and should do differently.
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Reviving Critical Planning Theory

Reviving Critical Planning Theory

Tore Øivin Sager

Routledge
2012
nidottu
Discussing some of the most vexing criticism of communicative planning theory (CPT), this book goes on to suggest how theorists and planners can respond to it. Looking at issues of power, politics and ethics in relation to planning, this book is for both critics and advocates of CPT, with lessons for all. With severe criticisms being raised against CPT, the need has arisen to systematically think through what responsibilities planning theorists might have for the end-uses of their theoretical work. Offering inventive proposals for amending the shortcomings of this widely adhered planning method, this book reflects on what communicative planning theorists and practitioners can and should do differently.
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Confidence, Likelihood, Probability

Confidence, Likelihood, Probability

Tore Schweder; Nils Lid Hjort

Cambridge University Press
2016
sidottu
This lively book lays out a methodology of confidence distributions and puts them through their paces. Among other merits, they lead to optimal combinations of confidence from different sources of information, and they can make complex models amenable to objective and indeed prior-free analysis for less subjectively inclined statisticians. The generous mixture of theory, illustrations, applications and exercises is suitable for statisticians at all levels of experience, as well as for data-oriented scientists. Some confidence distributions are less dispersed than their competitors. This concept leads to a theory of risk functions and comparisons for distributions of confidence. Neyman–Pearson type theorems leading to optimal confidence are developed and richly illustrated. Exact and optimal confidence distribution is the gold standard for inferred epistemic distributions. Confidence distributions and likelihood functions are intertwined, allowing prior distributions to be made part of the likelihood. Meta-analysis in likelihood terms is developed and taken beyond traditional methods, suiting it in particular to combining information across diverse data sources.
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Agrarian Crossings

Agrarian Crossings

Tore C. Olsson

PRINCETON UNIVERSITY PRESS
2017
sidottu
In the 1930s and 1940s, rural reformers in the United States and Mexico waged unprecedented campaigns to remake their countrysides in the name of agrarian justice and agricultural productivity. Agrarian Crossings tells the story of how these campaigns were conducted in dialogue with one another as reformers in each nation came to exchange models, plans, and strategies with their equivalents across the border. Dismantling the artificial boundaries that can divide American and Latin American history, Tore Olsson shows how the agrarian histories of both regions share far more than we realize. He traces the connections between the US South and the plantation zones of Mexico, places that suffered parallel problems of environmental decline, rural poverty, and gross inequities in land tenure. Bringing this tumultuous era vividly to life, he describes how Roosevelt's New Deal drew on Mexican revolutionary agrarianism to shape its program for the rural South. Olsson also looks at how the US South served as the domestic laboratory for the Rockefeller Foundation's "green revolution" in Mexico--which would become the most important Third World development campaign of the twentieth century--and how the Mexican government attempted to replicate the hydraulic development of the Tennessee Valley Authority after World War II. Rather than a comparative history, Agrarian Crossings is an innovative history of comparisons and the ways they affected policy, moved people, and reshaped the landscape.
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Agrarian Crossings

Agrarian Crossings

Tore C. Olsson

Princeton University Press
2020
pokkari
In the 1930s and 1940s, rural reformers in the United States and Mexico waged unprecedented campaigns to remake their countrysides in the name of agrarian justice and agricultural productivity. Agrarian Crossings tells the story of how these campaigns were conducted in dialogue with one another as reformers in each nation came to exchange models, plans, and strategies with their equivalents across the border.Dismantling the artificial boundaries that can divide American and Latin American history, Tore Olsson shows how the agrarian histories of both regions share far more than we realize. He traces the connections between the US South and the plantation zones of Mexico, places that suffered parallel problems of environmental decline, rural poverty, and gross inequities in land tenure. Bringing this tumultuous era vividly to life, he describes how Roosevelt’s New Deal drew on Mexican revolutionary agrarianism to shape its program for the rural South. Olsson also looks at how the US South served as the domestic laboratory for the Rockefeller Foundation’s “green revolution” in Mexico—which would become the most important Third World development campaign of the twentieth century—and how the Mexican government attempted to replicate the hydraulic development of the Tennessee Valley Authority after World War II.Rather than a comparative history, Agrarian Crossings is an innovative history of comparisons and the ways they affected policy, moved people, and reshaped the landscape.
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Democratic Planning and Social Choice Dilemmas

Democratic Planning and Social Choice Dilemmas

Tore Sager

Ashgate Publishing Limited
2002
sidottu
Using the economic approach of social choice theory, this unique book examines difficulties found in democratic processes involved in the creation and implementation of planning policies. Social choice theory focuses on the hard trade-offs to be made between rationality in decision-making on the one hand, and political values such as democracy, liberalism and freedom from manipulation on the other. As an institution can be seen as a set of rules, the focus on rules and procedures of collective choice makes social choice theory well suited for analysing important political aspects of planning institutions. Special attention is given to communicative planning and the logical reasons why all the desirable properties of dialogue cannot be simultaneously attained. The analysis provides original and significant new insights into the process and the institutions involved. It highlights weak spots of present planning techniques and procedures and suggests further steps towards institutionally enriched planning theory.
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The Ethics of Mobilities

The Ethics of Mobilities

Tore Sager

Ashgate Publishing Limited
2008
sidottu
With this book the international academic discourse on mobility is taken a step further, through the intertwined perspectives of different social sciences, engineering and the humanities. The Ethics of Mobilities departs from the recent interest in social surveillance, raised by the use of technology for the surveillance and control of mobility as well as for transport. It widens this theme to encompass a broad scale of issues, ranging from freedom and escape to social exclusion and control, thus raising important questions of ethics, identity and religion; questions that are dealt with by a diverse, yet structured range of chapters, arranged around the themes of ethics and religion, and freedom and control. Through their variety and diversity of perspectives, the chapters of this book offer a substantial interdisciplinary contribution to the socially and environmentally relevant discussion about what a technically and economically accelerating mobility does to life and how it might be transformed to sustain a more life-enhancing future. Ethics of Mobilities will excite not only international interest, but will also appeal to scholars across a wide range of disciplines, in fields as diverse as theology and engineering.
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Electromagnetic and Quantum Measurements

Electromagnetic and Quantum Measurements

Tore Wessel-Berg

Springer
2000
sidottu
It is a pleasure to write a foreword for Professor Tore Wessel-Berg's book, "Electromagnetic and Quantum Measurements: A Bitemporal Neoclassical Theory." This book appeals to me for several reasons. The most important is that, in this book, Wessel-Berg breaks from the pack. The distinguished astrophysicist Thomas Gold has written about the pressures on scientists to move in tight formation, to avoid having their legs nipped by the sheepdogs of science. This book demonstrates that Wessel-Berg is willing to take that risk. I confess that I do not sufficiently understand this book to be able to either agree or disagree with its thesis. Nevertheless, Wessel-Berg makes very cogent arguments for setting out on his journey. The basic equations of physics are indeed time-reversible. Our experience, that leads us to the concept of an "arrow of time," is derived from macro­ scopic phenomena, not from fundamental microscopic phenomena. For this reason, it makes very good sense to explore the consequences of treating microscopic phenomena on the assumption that forward time and backward time are equal.
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The Past Is Always Present

The Past Is Always Present

Tore Tvarnø Lind

Scarecrow Press
2011
muu
In The Past Is Always Present, Tore Tvarnø Lind examines the musical revival of Greek Orthodox chant at the monastery of Vatopaidi within the monastic society of Mount Athos, Greece. In particular, Lind focuses on the musical activities at the monastery and the meaning of the past in the monks' efforts at improving their musical performance practice through an emphasis on tradition. Based on a decade of intense fieldwork and extensive interviews with members of Athos' monastic community, Lind covers a vast array of topics. From musical notation and the Greek oral tradition to CD covers and music production, the tension between tradition and modernity in the musical activity of the Athonite community raises a clear challenge to the quest to bring together Orthodox spirituality and quietude with musical production. The Past Is Always Present addresses all of these matters by focusing on the significance and meaning of the local chanting style. As Lind argues, Byzantine chant cannot be fully grasped in musicological terms alone, outside the context of prayer. Yet because chant is fundamentally a way of communicating with God, the sound generated must be exactly right, pushing issues of music notation, theory, and performance practice to the forefront. Byzantine chant, Lind ultimately argues, is a modern phenomenon as the monastic communities of Mount Athos negotiate with the realities of modern Orthodox identity in Greece. By reporting on the musical revival activities of this remarkable community through the topics of notation, musical theory, drone-singing, and spiritual silence, Lind looks at the ways in which Athonite heritage is shaped, touching upon the Byzantine chant's contemporary relationship with practice of pilgrimage and the phenomenon of religious tourism. Offering unique insights into the monastic culture at Mount Athos, The Past Is Always Present is for those especially interested in sacred music, past and present Greek culture, monastic life, religious tourism, and the fields of ethnomusicology and anthropology.
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The Human Genome in Health and Disease

The Human Genome in Health and Disease

Tore Samuelsson

CRC Press Inc
2019
nidottu
The human genome is a linear sequence of roughly 3 billion bases and information regarding this genome is accumulating at an astonishing rate. Inspired by these advances, The Human Genome in Health and Disease: A Story of Four Letters explores the intimate link between sequence information and biological function. A range of sequence-based functional units of the genome are discussed and illustrated with inherited disorders and cancer. In addition, the book considers valuable medical applications related to human genome sequencing, such as gene therapy methods and the identification of causative mutations in rare genetic disorders.The primary audiences of the book are students of genetics, biology, medicine, molecular biology and bioinformatics. Richly illustrated with review questions provided for each chapter, the book helps students without previous studies of genetics and molecular biology. It may also be of benefit for advanced non-academics, which in the era of personal genomics, want to learn more about their genome.Key selling features:Molecular sequence perspective, explaining the relationship between DNA sequence motifs and biological functionAids in understanding the functional impact of mutations and genetic variantsMaterial presented at basic level, making it accessible to students without previous studies of genetics and molecular biologyRichly illustrated with questions provided to each chapter
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Dissonant Landscapes

Dissonant Landscapes

Tore Storvøld

WESLEYAN UNIVERSITY PRESS
2024
sidottu
Listening to the dissonances of nature and nationhood in modern Iceland. During the past three decades, Iceland has attained a strong presence in the world through its musical culture, with images of the nation being packaged and shipped out in melodies, harmonies, and rhythms. What 'Iceland' means for people, both at home and abroad, is conditioned by music and its ability to animate notions of nature and nationality. In six chapters that range from discussions of indie rock ballads to 'Nordic noir' television music, Dissonant Landscapes describes the capacity of musical expression to transform ideas about nature and nationality on the northern edges of Europe.
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Dissonant Landscapes

Dissonant Landscapes

Tore Storvøld

WESLEYAN UNIVERSITY PRESS
2024
nidottu
During the past three decades, Iceland has attained a strong presence in the world through its musical culture, with images of the nation being packaged and shipped out in melodies, harmonies, and rhythms. What 'Iceland' means for people, both at home and abroad, is conditioned by music and its ability to animate notions of nature and nationality. In six chapters that range from discussions of indie rock ballads to 'Nordic noir' television music, Dissonant Landscapes describes the capacity of musical expression to transform ideas about nature and nationality on the northern edges of Europe. **PRAISE** "Through a strong analysis and engaging writing, Størvold gives a nuanced insight into how exoticism was activated in relation to Icelandic music in the recent past." _~Kristín Loftsdóttir, author of Crisis and Coloniality at Europe's Margins: Creating Exotic Iceland_ "Dissonant Landscapes takes discussions of nature and the musical imagination to a new level of sophistication. With Iceland as the crucible of his investigations, Størvold shows how environmental awareness has infiltrated musical practices that evade easy categorization, but have almost unlimited potential to motivate listeners towards action." _~John Richardson, author of An Eye for Music: Popular Music and the Audiovisual Surreal_
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Partiality, Truth, and Persistence

Partiality, Truth, and Persistence

Tore Langholm

Centre for the Study of Language Information
1988
pokkari
In recent years, 'semantical partiality' has emerged as an important concept in philosophical logic as well as in the study of natural language semantics. Despite the many applications, however, a number of mathematically intriguing questions associated with this concept have received only very limited attention. Partiality, Truth, and Persistence is a study in spatial model theory, the theory of partially defined models. First, with the introduction of truth value gaps in semantics, there are many ways to generalize the classical truth definition for the sentences of a first order predicate language. We know what it means for a sentence to be true or false in a classical, complete model, but how do we extend this relation when partial models are introduced? Various alternatives exist, and a detailed comparison is carried out between them. Since these studies concern a full first order predicate language, many distinctions appear that do not arise in the case of pure propositional logic.A condition of monotonicity or 'persistence' of truth relative to partial models has a prominent position among conditions that are not expressible in the framework of standard, complete model theory. The final chapter investigates the relation between such conditions and expressibility properties in general. These discussions culminate with a combined Lindstrom and persistence characterization theorem. Tore Langholm is a research fellow in mathematics at the University of Oslo. He is a co-author of Situations, Language and Logic.
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Partiality, Truth, and Persistence

Partiality, Truth, and Persistence

Tore Langholm

Centre for the Study of Language Information
1988
sidottu
In recent years, 'semantical partiality' has emerged as an important concept in philosophical logic as well as in the study of natural language semantics. Despite the many applications, however, a number of mathematically intriguing questions associated with this concept have received only very limited attention. Partiality, Truth, and Persistence is a study in spatial model theory, the theory of partially defined models. First, with the introduction of truth value gaps in semantics, there are many ways to generalize the classical truth definition for the sentences of a first order predicate language. We know what it means for a sentence to be true or false in a classical, complete model, but how do we extend this relation when partial models are introduced? Various alternatives exist, and a detailed comparison is carried out between them. Since these studies concern a full first order predicate language, many distinctions appear that do not arise in the case of pure propositional logic.A condition of monotonicity or 'persistence' of truth relative to partial models has a prominent position among conditions that are not expressible in the framework of standard, complete model theory. The final chapter investigates the relation between such conditions and expressibility properties in general. These discussions culminate with a combined Lindstrom and persistence characterization theorem. Tore Langholm is a research fellow in mathematics at the University of Oslo. He is a co-author of Situations, Language and Logic.
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Language Change and Cognitive Linguistics

Language Change and Cognitive Linguistics

Tore Nesset

Cambridge University Press
2022
pokkari
The purpose of this Cambridge Element is to bring together three subfields of the language sciences: cognitive, historical (diachronic), and Russian linguistics. Although diachrony has inspired a number of important works in recent years, historical linguistics is still underrepresented in cognitive linguistics, and the most influential publications mainly concern the history of English. This is an unfortunate bias, especially since its lack of morphological complexity makes English a typologically unusual language. In this Cambridge Element, the author demonstrates that Russian has a lot to offer the historically oriented cognitive linguist, given its well-documented history and complex phonology and morpho-syntax. Through seven case studies the author illustrates the relevance of four basic tenets of Cognitive Grammar: the cognitive, semiotic, network, and usage-based commitments.
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Planetary Pynchon

Planetary Pynchon

Tore Rye Andersen

Cambridge University Press
2023
sidottu
While Thomas Pynchon is usually described as an American author who primarily writes about American reality, Planetary Pynchon: History, Modernity, and the Anthropocene argues that his major novels, Gravity's Rainbow, Mason & Dixon, and Against the Day, can profitably be read as a global trilogy that presents a coherent historical account of how the emergence and spread of European modernity across the world have had devastating consequences for the planet and its inhabitants. This book sets a new agenda in Pynchon studies, charting his early anticipation of anthropocenic and planetary ideas, including globalization's demand for constant growth. It combines close textual readings with broad perspectives on large thematic arcs and stylistic developments across Pynchon's entire career as well as an extensive dialogue with the rich reception of his work.
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