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1000 tulosta hakusanalla Deborah Wallace

Right-to-Work Laws and the Crumbling of American Public Health

Right-to-Work Laws and the Crumbling of American Public Health

Deborah Wallace; Rodrick Wallace

Springer International Publishing AG
2018
sidottu
This book discusses the socioeconomic effects of Right-to-Work (RTW) laws on state populations. RTW laws forbid requiring union membership even at union-represented worksites. The core of the 22 long-term RTW states was the Confederacy, cultural descendants of rigidly hierarchical agrarian feudal England. RTW laws buttress hierarchy and power imbalance which unions minimize at the worksite and by encouraging higher educational attainment, social mobility, and individual empowerment through group validation. Contrary to claims of RTW proponents, RTW and non-RTW states do not differ significantly in unemployment rates.RTW states have higher poverty rates, lower median household incomes, and lower educational attainment on average and median than non-RTW states. RTW states on average and median have lower life expectancy, higher obesity prevalence, and higher rates of all-cause mortality, early mortality from chronic conditions, child mortality, and risk behaviors than non-RTW states. The higher mortality rates result in startlingly higher annual numbers of years of life lost before age 75. Stroke mortality at age 55-64 in RTW states results in nearly 10,000 years annually lost in excess of what it would be if the mortality rate were that of non-RTW states.A review of respected publications describes the physiological mechanisms and epidemiology of accelerated aging due to socioeconomic stress. Unions challenge hierarchy directly at work-sites and indirectly through encouraging college education, social mobility, and community and political engagement. How startling that feudal hierarchy lives in 21st century America, shaping vast differences between states in macro- and micro-economics, educational attainment, innovation, life expectancy, obesity prevalence, chronic disease mortality, infant and child mortality, risk behaviors, and other public health markers! Readers will gain insight about the coming clash between feudal individualism and adaptive collectivism, and, in the last chapter, on ways to win the clash by “missionary” work for collectivism.
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Right-to-Work Laws and the Crumbling of American Public Health

Right-to-Work Laws and the Crumbling of American Public Health

Deborah Wallace; Rodrick Wallace

Springer International Publishing AG
2019
nidottu
This book discusses the socioeconomic effects of Right-to-Work (RTW) laws on state populations. RTW laws forbid requiring union membership even at union-represented worksites. The core of the 22 long-term RTW states was the Confederacy, cultural descendants of rigidly hierarchical agrarian feudal England. RTW laws buttress hierarchy and power imbalance which unions minimize at the worksite and by encouraging higher educational attainment, social mobility, and individual empowerment through group validation. Contrary to claims of RTW proponents, RTW and non-RTW states do not differ significantly in unemployment rates.RTW states have higher poverty rates, lower median household incomes, and lower educational attainment on average and median than non-RTW states. RTW states on average and median have lower life expectancy, higher obesity prevalence, and higher rates of all-cause mortality, early mortality from chronic conditions, child mortality, and risk behaviors than non-RTW states. The higher mortality rates result in startlingly higher annual numbers of years of life lost before age 75. Stroke mortality at age 55-64 in RTW states results in nearly 10,000 years annually lost in excess of what it would be if the mortality rate were that of non-RTW states.A review of respected publications describes the physiological mechanisms and epidemiology of accelerated aging due to socioeconomic stress. Unions challenge hierarchy directly at work-sites and indirectly through encouraging college education, social mobility, and community and political engagement. How startling that feudal hierarchy lives in 21st century America, shaping vast differences between states in macro- and micro-economics, educational attainment, innovation, life expectancy, obesity prevalence, chronic disease mortality, infant and child mortality, risk behaviors, and other public health markers! Readers will gain insight about the coming clash between feudal individualism and adaptive collectivism, and, in the last chapter, on ways to win the clash by “missionary” work for collectivism.
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Farming Human Pathogens

Farming Human Pathogens

Rodrick Wallace; Deborah Wallace; Robert G. Wallace

Springer-Verlag New York Inc.
2009
sidottu
Farming Human Pathogens: Ecological Resilience and Evolutionary Process introduces a cutting-edge mathematical formalism based on the asymptotic limit theorems of information theory to describe how punctuated shifts in mesoscale ecosystems can entrain patterns of gene expression and organismal evolution. The authors apply the new formalism toward characterizing a number of infectious diseases that have evolved in response to the world as humans have made it. Many of the human pathogens that are emerging out from underneath epidemiological control are 'farmed' in the metaphorical sense, as the evolution of drug-resistant HIV makes clear, but also quite literally, as demonstrated by avian influenza's emergence from poultry farms in southern China. The most successful pathogens appear able to integrate selection pressures humans have imposed upon them from a variety of socioecological scales. The book also presents a related treatment of Eigen's Paradox and the RNA 'error catastrophe' that bedevils models of the origins of viruses and of biological life itself.
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Farming Human Pathogens

Farming Human Pathogens

Rodrick Wallace; Deborah Wallace; Robert G. Wallace

Springer-Verlag New York Inc.
2010
nidottu
Farming Human Pathogens: Ecological Resilience and Evolutionary Process introduces a cutting-edge mathematical formalism based on the asymptotic limit theorems of information theory to describe how punctuated shifts in mesoscale ecosystems can entrain patterns of gene expression and organismal evolution. The authors apply the new formalism toward characterizing a number of infectious diseases that have evolved in response to the world as humans have made it. Many of the human pathogens that are emerging out from underneath epidemiological control are 'farmed' in the metaphorical sense, as the evolution of drug-resistant HIV makes clear, but also quite literally, as demonstrated by avian influenza's emergence from poultry farms in southern China. The most successful pathogens appear able to integrate selection pressures humans have imposed upon them from a variety of socioecological scales. The book also presents a related treatment of Eigen's Paradox and the RNA 'error catastrophe' that bedevils models of the origins of viruses and of biological life itself.
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Gene Expression and Its Discontents

Gene Expression and Its Discontents

Rodrick Wallace; Deborah Wallace

Springer-Verlag New York Inc.
2014
nidottu
Gene Expression and its Discontents examines a class of probability models describing how epigenetic context affects gene expression and organismal development, using the asymptotic limit theorems of information theory in a highly formal manner. Taking classic results on spontaneous symmetry breaking abducted from statistical physics in groupoid, rather than group, circumstances, the work suggests that epigenetic information sources act as analogs to a tunable catalyst, directing development into different characteristic pathways according to the structure of external signals. The results have significant implications for epigenetic epidemiology, in particular for understanding how environmental stressors, in a large sense, can induce a broad spectrum of developmental disorders in humans. The authors then apply the perspective to a number of chronic diseases broadly associated with obesity, using data at different scales of observation.
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Mathematical Approach To Multilevel, Multiscale Health Interventions, A: Pharmaceutical Industry Decline And Policy Response

Mathematical Approach To Multilevel, Multiscale Health Interventions, A: Pharmaceutical Industry Decline And Policy Response

Rodrick Wallace; Deborah Wallace

Imperial College Press
2013
sidottu
This book, based on published studies, takes a unique perspective on the 30-year collapse of pharmaceutical industry productivity in the search for small molecule “magic bullet” interventions. The relentless escalation of inflation-adjusted cost per approved medicine in the United States — from $200 million in 1950 to $1.2 billion in 2010 — has driven industry giants to, at best, slavish imitation in drug design, and at worst, abandonment of research and embracing of widespread fraud in consumer marketing.The book adapts formalism across a number of disciplines to the strategy for design of mutilevel interventions, focusing first on molecular, cellular, and larger scale examples, and then extending the argument to the simplifications provided by the dominant role of social and cultural structures and processes in individual and population patterns of health and illness.In place of “magic bullets”, we must now apply “magic strategies” that act across both the scale and level of organization. This book provides an introductory roadmap to the new tools that will be needed for the design of such strategies.
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Gene Expression and Its Discontents

Gene Expression and Its Discontents

Rodrick Wallace; Deborah Wallace

Springer International Publishing AG
2016
sidottu
This book describes how epigenetic context, in a large sense, affects gene expression and the development of an organism, using the asymptotic limit theorems of information theory to construct statistical models useful in data analysis. The approach allows deep understanding of how embedding context affects development. We find that epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. In sum, environmental stressors can induce a broad spectrum of developmental dysfunctions, and the book explores a number of pandemic chronic diseases, using U.S. data at different scales and levels of organization. In particular, we find the legacy of slavery has been grossly compounded by accelerating industrial decline and urban decay. Individual chapters are dedicated to obesity and its sequelae, coronary heart disease, cancer, mental disorders, autoimmune dysfunction, Alzheimer’s disease, and other conditions. Developmental disorders are driven by environmental factors channeled by historical trajectory and are unlikely to respond to medical interventions at the population level in the face of persistent individual and community stress. Drugs powerful enough to affect deleterious epigenetic programming will likely have side effects leading to shortened lifespan. Addressing chronic conditions and developmental disorders requires significant large-scale changes in public policy and resource allocation.
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Gene Expression and Its Discontents

Gene Expression and Its Discontents

Rodrick Wallace; Deborah Wallace

Springer International Publishing AG
2018
nidottu
This book describes how epigenetic context, in a large sense, affects gene expression and the development of an organism, using the asymptotic limit theorems of information theory to construct statistical models useful in data analysis. The approach allows deep understanding of how embedding context affects development. We find that epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. In sum, environmental stressors can induce a broad spectrum of developmental dysfunctions, and the book explores a number of pandemic chronic diseases, using U.S. data at different scales and levels of organization. In particular, we find the legacy of slavery has been grossly compounded by accelerating industrial decline and urban decay. Individual chapters are dedicated to obesity and its sequelae, coronary heart disease, cancer, mental disorders, autoimmune dysfunction, Alzheimer’s disease, and other conditions. Developmental disorders are driven by environmental factors channeled by historical trajectory and are unlikely to respond to medical interventions at the population level in the face of persistent individual and community stress. Drugs powerful enough to affect deleterious epigenetic programming will likely have side effects leading to shortened lifespan. Addressing chronic conditions and developmental disorders requires significant large-scale changes in public policy and resource allocation.
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Deborah

Deborah

Cathy Phythian

Trilogy Christian Publishing
2020
pokkari
God is calling mature women of faith to rise up and pray for the younger generations. Also, we need to tell them what we have learned about God and His wonders. This is our time to use the preparation we have experienced to lead the young army of God into battle as Deborah did with confidence.
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Deborah

Deborah

Phyllis J Stevens

Illumify Media
2023
pokkari
The children of Israel lived in fear of evil commander Sisera and the Canaanite army. Every day, the army stole their food and abused the people.Then the Spirit of the Lord came upon Deborah to deliver Israel. She sent word to Barak to lead the Israelite army in battle against the Canaanites. But Barak was afraid."If you will go with me, then I will go," he said. "But if you do not go, I will not go.""I'll go with you," Deborah said. "But the victory will not lead to your glory. It will be given to a woman."In Deborah, Phyllis Stevens retells the story of the courageous judge, prophetess, and military commander. You'll discover- Why God sent Deborah along with Barak to lead the Israelite army.- How God used the force of nature to fight for Israel.- How God used a single woman to kill Sisera.Read Deborah because the highest form of worship is obedience.
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