Nina + Simone reveals a story about family. It follows the journey of a gifted Black musician who is haunted by the ghost of his mother. In his journey, which includes his striving to achieve fame and success in a cutthroat business, he encounters two women who are identical twins. These sisters are amateur singers who possess a powerful ability to connect with audiences in small, out-of-the-way venues. When they have an opportunity to compete for a major performance, the twins approach the musician to help them prepare. While at first reluctant, the musician grows to appreciate and develop the talent of these women. He also begins to see them as his true family, as never in his life has he been loved so unconditionally. Just as they are about to find great success together, the world is torn asunder through plague and social disruption. The musician loses contact with his new-found family. The greatest challenge of his life begins when he leaves the security of his small, sanctuary-like studio to search for the twin sisters in a hostile world.
