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Waiting Time of Jobs Models in n x 2 Flow Shop Scheduling

Waiting Time of Jobs Models in n x 2 Flow Shop Scheduling

Deepak Gupta; Bharat Goyal

LAP Lambert Academic Publishing
2020
pokkari
Scheduling of jobs on machines can be observed in many real life problems. The book covers up the basic concepts of OR and Scheduling theory. The book focuses on the Flow Shop Scheduling Models in two stage where the objective is to minimize the Idle Time of Jobs. The job block concept in these models have been well thought of. The models considered here are specially structured in the sense that the processing times of both the machines are not on the whole arbitrary but have a definite relationship with one another.
Synthesis, evaluation of some benzoxazoles derivatives

Synthesis, evaluation of some benzoxazoles derivatives

Deepak Shrivastava

LAP Lambert Academic Publishing
2020
pokkari
5methyl substituted phenol benzoxazoles derivatives were synthesized by the reaction of 5 methyl 2 amino phenol with various aldehydes in the presence of Ethyl alcohol and lead tetra acetate.all the compounds were characterized by their analytical and spectral data (IR,1HNMR and Mass). synthesized compounds have been evaluated for their antimicrobial and antifungal activities by gram + and gram - and C. Albicans benzoxazoles derivatives shown significant activity as compared to Griseofulvin standard drugs.
Synthesized & evaluate of hetero cyclic compounds different activity

Synthesized & evaluate of hetero cyclic compounds different activity

Deepak Shrivastava

LAP Lambert Academic Publishing
2020
pokkari
Advancement of medicinal chemistry in this century has been possible due to the integration of various disciplines like organic chemistry, pharmacology, molecular biology, biochemistry and other allied subjects that work hand in hand as a team.A successful medical agent has its birth in stages viz. chemical synthesis, screening for activity/activities, toxicological studies, metabolic studies, clinical trials of a tolerance tests, teratogenic tests, QSAR studies and so on. The biological action of a drug occurs due to the interaction of molecule with other specific molecules or receptors or enzymes. Ariens later elaborated the concept of receptor theory.The isosteric replacement of -O-, -S- and -N- gives rise to the compounds, benzoxazole, benzothiazole and benzimidazole respectively
Optimization Technique For Recent Dosage Form Development

Optimization Technique For Recent Dosage Form Development

Deepak Shrivastava

LAP Lambert Academic Publishing
2020
pokkari
Conventional tablets available in market are not suitable where quick onset of action is required. Besides, the conventional tablets also show poor patient compliance particularly by the geriatric and pediatric patients who experience difficulty in swallowing, and by those who are bed ridden or who are traveling and do not have an easy access of water. To provide the patients with the most conventional mode of administration, there was a need to develop rapidly disintegrating dosageIn this study, tablets of Fexofenadine HCl were prepared by direct compression, where SSG, CCS, KCL, Xanthan Gum and Ludiflash were used as disintegrants.
Carriers For Drug Delivery System

Carriers For Drug Delivery System

Deepak Shrivastava

LAP Lambert Academic Publishing
2020
pokkari
Novel drug delivery system aims to deliver the drug at a rate directed by the needs of the body during the period of treatment, and channel the active entity to the site of action. At present, no available drug delivery system behaves ideally achieving all the lofty goals, but sincere attempts have been made to achieve them through novel approaches in drug delivery. A number of novel drug delivery systems have emerged encompassing various routes of administration, to achieve controlled and targeted drug delivery. Encapsulation of the drug in vesicular structures is one such system, which can be predicted to prolong the existence of the drug in systemic circulation, and reduce the toxicity, if selective uptake can be achieved. Consequently a number of vesicular drug delivery systems such as liposomes, niosomes, transfersomes, and pharmacosomes were developed. Advances have since been made in the area of vesicular drug delivery, leading to the development of systems that allow drug targeting, and the sustained or controlled release of conventional medicines.
Synthesize Isoniazid Derivatives And Evaluate Different Activity

Synthesize Isoniazid Derivatives And Evaluate Different Activity

Deepak Shrivastava

LAP Lambert Academic Publishing
2020
pokkari
The current approach is to develop new and effective antituberculotic agents by sunthesizing new isoniazid derivatives.Isoniazid is used as anti-tuberculotic drug alon and with the combination with other antibiotics. The review of literature survey reveals that maximum of antimicrobial agents contains heterocyclic rings in their structure. The antimicrobial activity of many antibiotics is increased by attaching heterocyclic rings like azetidine, thiozole, oxazole, indole, imidazole etc with the antibiotics.number of potent medicinal agents consists of azetidine, thiazolidine, oxazolidine and imidazolidine ring in their structure having good antimicrobial potency. From the consideration of the above factors research work was aimed to synthesize isoniazid derivatives and evaluate for antimicrobial, antifungal and anti-tuberculotic activity as compared to standard drugs.