Bioinformatics encompasses a broad and ever-changing range of activities involved with the management and analysis of data from molecular biology experiments. Despite the diversity of activities and applications, the basic methodology and core tools needed to tackle bioinformatics problems is common to many projects. This unique book provides an invaluable introduction to three of the main tools used in the development of bioinformatics software - Perl, R and MySQL - and explains how these can be used together to tackle the complex data-driven challenges that typify modern biology. These industry standard open source tools form the core of many bioinformatics projects, both in academia and industry. The methodologies introduced are platform independent, and all the examples that feature have been tested on Windows, Linux and Mac OS. Building Bioinformatics Solutions is suitable for graduate students and researchers in the life sciences who wish to automate analyses or create their own databases and web-based tools. No prior knowledge of software development is assumed. Having worked through the book, the reader should have the necessary core skills to develop computational solutions for their specific research programmes. The book will also help the reader overcome the inertia associated with penetrating this field, and provide them with the confidence and understanding required to go on to develop more advanced bioinformatics skills.
Bioinformatics encompasses a broad and ever-changing range of activities involved with the management and analysis of data from molecular biology experiments. Despite the diversity of activities and applications, the basic methodology and core tools needed to tackle bioinformatics problems is common to many projects. This unique book provides an invaluable introduction to three of the main tools used in the development of bioinformatics software - Perl, R and MySQL - and explains how these can be used together to tackle the complex data-driven challenges that typify modern biology. These industry standard open source tools form the core of many bioinformatics projects, both in academia and industry. The methodologies introduced are platform independent, and all the examples that feature have been tested on Windows, Linux and Mac OS. Building Bioinformatics Solutions is suitable for graduate students and researchers in the life sciences who wish to automate analyses or create their own databases and web-based tools. No prior knowledge of software development is assumed. Having worked through the book, the reader should have the necessary core skills to develop computational solutions for their specific research programmes. The book will also help the reader overcome the inertia associated with penetrating this field, and provide them with the confidence and understanding required to go on to develop more advanced bioinformatics skills.
As the Eurozone faces an uncertain future and Obama struggles to demonstrate that America still has a superpower status, this book challenges the widespread perception that Brazil, Russia, India and China are becoming global economic and political powers, instead forecasting a decline rooted in excessive inequality and insufficient innovation.
While artificial intelligence (AI), robots, bio-technologies and digital media are transforming work, culture, and social life, there is little understanding of or agreement about the scope and significance of this change. This new interpretation of the ‘great transformation’ uses history and evolutionary theory to highlight the momentous shift in human consciousness taking place. Only by learning from recent crises and rejecting technological determinism will governments and communities redesign social arrangements that ensure we all benefit from the new and emerging technologies. The book documents the transformations under way in financial markets, entertainment, and medicine, affecting all aspects of work and social life. It draws on historical sociology and co-evolutionary theory arguing that the radical evolution of human consciousness and social life now under way is comparable with, if not greater than, the agrarian revolution (10000 BCE), the explosion of science, philosophy, and religion in the Axial Age (600 BCE), and the recent Industrial Revolution. Turning to recent major socio-economic crisis, and asking what can be learnt from them, the answer is we cannot afford this time around to repeat the failures of elites and theoretical systems such as economics to attend appropriately to radical change. We need to think beyond the constraints of determinist and reductionist explanations and embrace the idea of deep freedom. This book will appeal to educators, social scientists, policy-makers, business leaders, and students. It concludes with social design principles that can inform deliberative processes and new social arrangements that ensure everyone benefits from the affordances of the new and emerging technologies.
Anxiety about unemployment, homelessness, poverty and crime has always been around. Today, governments, experts and the media spend a lot of time talking about people at risk, the measurement and prediction of risk factors, encouraging resiliency and the need for early intervention. What are the politics, origins and meanings behind risk talk? Is the discovery and management of risk factors capable of offering real solutions? This lively, provocative book asks these questions by examining youth employment, homelessness and juvenile crime. It is a must-read for policy makers, human service workers, researchers and anyone interested in the key social issues of our time.
While artificial intelligence (AI), robots, bio-technologies and digital media are transforming work, culture, and social life, there is little understanding of or agreement about the scope and significance of this change. This new interpretation of the ‘great transformation’ uses history and evolutionary theory to highlight the momentous shift in human consciousness taking place. Only by learning from recent crises and rejecting technological determinism will governments and communities redesign social arrangements that ensure we all benefit from the new and emerging technologies. The book documents the transformations under way in financial markets, entertainment, and medicine, affecting all aspects of work and social life. It draws on historical sociology and co-evolutionary theory arguing that the radical evolution of human consciousness and social life now under way is comparable with, if not greater than, the agrarian revolution (10000 BCE), the explosion of science, philosophy, and religion in the Axial Age (600 BCE), and the recent Industrial Revolution. Turning to recent major socio-economic crisis, and asking what can be learnt from them, the answer is we cannot afford this time around to repeat the failures of elites and theoretical systems such as economics to attend appropriately to radical change. We need to think beyond the constraints of determinist and reductionist explanations and embrace the idea of deep freedom. This book will appeal to educators, social scientists, policy-makers, business leaders, and students. It concludes with social design principles that can inform deliberative processes and new social arrangements that ensure everyone benefits from the affordances of the new and emerging technologies.
As the Eurozone faces an uncertain future and Obama struggles to demonstrate that America still has a superpower status, this book challenges the widespread perception that Brazil, Russia, India and China are becoming global economic and political powers, instead forecasting a decline rooted in excessive inequality and insufficient innovation.
The Irish composer, Ina Boyle (1889-1967), was born in Enniskerry, Co. Wicklow, where she enjoyed a sheltered childhood as a member of an Anglo-Irish family with roots in the medical, military and diplomatic professions. Her first music teacher was her clergyman father, who made violins for a hobby. She started to compose from an early age and soon found a passion for music that lasted a lifetime, spanning two world wars, the 1916 rebellion, the war of independence, the civil war and the economic war.Ina Boyle studied privately in Dublin with C.H. Kitson and Percy Buck, she had her first success in 1919 when her orchestral rhapsody, `The magic harp', which was selected for publication by the prestigious Carnegie United Kingdom Trust and was performed by the London Symphony Orchestra, conducted by Adrian Boult. From 1923, realising the need to expand her musical horizons, she visited London for composition lessons with Ralph Vaughan Williams whenever family duties allowed, until her travels were curtailed by the outbreak of the Second World War. Vaughan Williams thought highly of her works but, despite her best efforts to promote them, few were performed in public. During the 1940s some of her orchestral music was broadcast on Radio Eireann in a series of programmes on Irish composers. After the death of her father in 1951, she was again free to travel to London while devoting the rest of her life to composition. As one of twentieth-century Ireland's most prolific composers and the first Irishwoman to undertake a symphony, a concerto and a ballet, this first book on the life and music of Ina Boyle is long overdue.
Innovation matters – being able to create value from ideas is crucial to survival and growth. But while any organization might get lucky once being able to repeat the trick requires learning and developing particular ways of working which enable the process. Over a hundred years of research and practical experience now provides a knowledge base from which we can draw to help develop such approaches. But how do we move from prescription to implementation? And how does the innovation challenge play out over the lifetime of an organization? How does it renew its capability to innovate and do so against a background of dramatically changing markets, technologies and social trends? This book draws on a detailed history of a large German company (HELLA ), now active in over 35 countries, employing 34,000 people. It didn't start out that way, it began as an entrepreneurial start-up in the late 19th century in the (then) uncertain early days of the car industry. It moved from selling whips and other buggy accessories for horse-drawn carriages to horns and lamps for the new-fangled motor cars beginning to appear on the roads of north-western Germany. The journey since then has been one of innovation – in products and processes, in entering new markets, in adding services to its products, and in changing its underlying business models. Survival for over a hundred years is not an accident – it has been built on learning how to innovate and on constantly challenging and updating those models.
New updated edition of the bestselling cat behaviour bookDo you want to understand why your cat does the things it does? Claire Bessant, the original cat whisperer, teaches you how to get inside the mind of your cat
Thought-Forms, the standpoint of Theosophy, describes the visualization of thoughts, experiences, emotions and music.In 1895, the authors began to investigate "the subtle matter of the universe." They were interested in the human mind as, according their claim, the workings of the mind "extrudes into the external world" as expressed by "thought-forms."In September 1896, Besant described how "two clairvoyant Theosophists" had started "observing the substance of thought." She published an article titled "Thought-Forms" in the Theosophical Society's journal describing these experiences. The article eventually was expanded upon to produce this "small but influential book," first published in 1901, which contains colour pictures of thought-forms that the authors said are created "in subtle spirit-matter."This new edition includes all the illustrations in either colour or black and white as they were originally published.
Born to (W)alk (i)n (N)ewness (WIN)Is a reflection of the voice of my wounded overlooked and unheard inner child. As a result of trauma suffered at a very very young age, I spent the majority of my life looking and searching for my identity. I was living a life of having sex outside of marriage. This sent me down a dark path of situational depression. I found myself dealing with depression, a miscarriage, unemployment, homelessness, and divorce.There was no one to call on. No one to help. So, I turned to God with a pure and true heart. This is where I found my strength and healing to overcome the wounds and afflictions of my lost, wounded, broken, battered, and confused inner child.Today, I am healing through and beyond the anger and pain that once held me bound. We overcome by our testimony. Born to (W)alk (i)n (N)ewness (WIN) is a part of mine.
