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646 tulosta hakusanalla Alok Mukerjee

Formulierung Und Charakterisierung Von Nano-Strukturierten Lipidträgern

Formulierung Und Charakterisierung Von Nano-Strukturierten Lipidträgern

Bhawna Sharma; Iti Chauhan; Alok Pratap Singh

Verlag Unser Wissen
2023
pokkari
F r den UV-Schutz wurde Lutein erfolgreich topisch mithilfe von Gelen verabreicht, die mit der nanostrukturierten Lipidtr gertechnologie (NLC) hergestellt wurden. Arzneimittel und ihre m glichen Hilfsstoffe wurden w hrend der Vorformulierungsstudien mithilfe von Methoden wie organoleptischer Beurteilung, Schmelzpunktanalyse, UV-sichtbaren Spektren, L slichkeitsstudien, Verteilungskoeffizienten und Fourier-Transformations-Infrarot-Analyse (FT-IR) auf NLC untersucht. Nachdem das Arzneimittel erfolgreich war Charakterisiert wurde die Formulierungsentwicklung durchgef hrt, um feste und fl ssige Lipide, das Verh ltnis von festen Lipiden zu fl ssigen Lipiden, Tensid- und Co-Tensidkonzentrationen, die Formulierungstechnik und Prozessfaktoren, d. h. R hrgeschwindigkeit, R hrzeit und Homogenisierungszyklen, auszuw hlen und zu optimieren. Nach der Optimierung der Prozessparameter wurde eine Rezepturtabelle erstellt und NLC entsprechend erstellt. Um die optimale NLC-Formulierung zu entwickeln, wurden die Charakterisierungen der hergestellten NLC-Formulierungen hinsichtlich Form und Oberfl chenmorphologie (TEM), Partikelgr e, Zetapotenzial, %-Einschlusseffizienz und In-vitro-Freisetzungstests bewertet. Die optimierte Lutein-NLC-Formulierung hat eine Partikelgr e von 81,64 nm, ein Zetapotential von -14,1 mV.
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Formulation Et Caractérisation d'Un Support Lipidique Nano-Structuré

Formulation Et Caractérisation d'Un Support Lipidique Nano-Structuré

Bhawna Sharma; Iti Chauhan; Alok Pratap Singh

Editions Notre Savoir
2023
pokkari
Pour la protection contre les UV, la lut ine a t administr e avec succ s par voie topique l'aide de gels constitu s de la technologie des supports lipidiques nanostructur s (NLC). Les m dicaments et leurs excipients possibles ont t examin s pour la NLC au cours d' tudes de pr formulation l'aide de m thodes telles que l' valuation organoleptique, l'analyse du point de fusion, les spectres UV-Visible, les tudes de solubilit , le coefficient de partage et l'analyse par transform e de Fourier-Infrarouge (FT-IR). Une fois le m dicament caract ris avec succ s, le d veloppement de la formulation a t r alis pour s lectionner et optimiser les lipides solides et liquides, le rapport lipide solide/lipide liquide, les concentrations de tensioactifs et de co-tensioactifs, la technique de formulation et les facteurs de processus, savoir la vitesse d'agitation, le temps d'agitation et l'homog n isation. cycles. Suite l'optimisation des param tres du processus, un tableau de formulation a t cr et des NLC ont t produites de mani re appropri e. Afin de d velopper la formulation NLC optimale, les caract risations des formulations NLC produites ont t valu es pour la forme et la morphologie de surface (TEM), la taille des particules, le potentiel z ta, le % d'efficacit de pi geage et les tests de lib ration in vitro. La formulation optimis e de lut ine NLC a un taille de particule de 81,64 nm, potentiel z ta de -14,1 mV.
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Formulação E Caracterização de Um Transportador Lipídico Nano-Estruturado

Formulação E Caracterização de Um Transportador Lipídico Nano-Estruturado

Bhawna Sharma; Iti Chauhan; Alok Pratap Singh

Edicoes Nosso Conhecimento
2023
pokkari
Para prote o UV, a lute na foi administrada topicamente com sucesso usando g is feitos de tecnologia de transportador lip dico nanoestruturado (NLC). Os medicamentos e seus poss veis excipientes foram selecionados para NLC durante estudos de pr -formula o usando m todos como avalia o organol ptica, an lise de ponto de fus o, espectro UV-Vis vel, estudos de solubilidade, coeficiente de parti o e an lise de infravermelho por transformada de Fourier (FT-IR). Depois que o medicamento foi caracterizado com sucesso, o desenvolvimento da formula o foi realizado para selecionar e otimizar lip dios s lidos e l quidos, propor o de lip dios s lidos para lip dios l quidos, concentra es de surfactante e co-surfactante, t cnica de formula o e fatores de processo, ou seja, velocidade de agita o, tempo de agita o e homogeneiza o ciclos. Ap s a otimiza o dos par metros do processo, uma tabela de formula o foi criada e os NLC foram produzidos adequadamente. A fim de desenvolver a formula o NLC ideal, as caracteriza es das formula es NLC produzidas foram avaliadas quanto forma e morfologia da superf cie (TEM), tamanho de part cula, potencial zeta, % de efici ncia de aprisionamento e testes de libera o in vitro. tamanho de part cula de 81,64 nm, potencial zeta de -14,1 mV.
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Formulazione E Caratterizzazione Di Un Vettore Lipidico Nano-Strutturato

Formulazione E Caratterizzazione Di Un Vettore Lipidico Nano-Strutturato

Bhawna Sharma; Iti Chauhan; Alok Pratap Singh

Edizioni Sapienza
2023
pokkari
Per la protezione UV, la luteina stata somministrata con successo per via topica utilizzando gel realizzati con tecnologia di trasporto lipidico nanostrutturato (NLC). I farmaci e i loro possibili eccipienti sono stati sottoposti a screening per l'NLC durante gli studi di preformulazione utilizzando metodi quali valutazione organolettica, analisi del punto di fusione, spettri UV-visibile, studi di solubilit , coefficiente di partizione e analisi dell'infrarosso con trasformata di Fourier (FT-IR). Dopo che il farmaco stato caratterizzato con successo, stato effettuato lo sviluppo della formulazione per selezionare e ottimizzare i lipidi solidi e liquidi, il rapporto lipidi solidi/lipidi liquidi, le concentrazioni di tensioattivo e co-tensioattivo, la tecnica di formulazione e i fattori di processo, ovvero velocit di agitazione, tempo di agitazione e omogeneizzazione. cicli. A seguito dell'ottimizzazione dei parametri di processo, stata creata una tabella di formulazione e gli NLC sono stati prodotti opportunamente. Al fine di sviluppare la formulazione NLC ottimale, le caratterizzazioni delle formulazioni NLC prodotte sono state valutate per forma e morfologia superficiale (TEM), dimensione delle particelle, potenziale zeta, % di efficienza di intrappolamento e test di rilascio in vitro. La formulazione ottimizzata di luteina NLC ha un dimensione delle particelle di 81,64 nm, un potenziale zeta di -14,1 mV.
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Hidrogéis fabricados com apigenina

Hidrogéis fabricados com apigenina

Sushil Kumar Kashaw; Rajesh Shukla; Alok Pal Jain

Edicoes Nosso Conhecimento
2024
pokkari
A ferida uma rutura da integridade epitelial da pele que resulta de uma agress o ou de um traumatismo e que pode ser seguida de uma perturba o da estrutura e do papel do tecido normal subjacente. Foi afirmado que a hiperglicemia tem um efeito t xico na cicatriza o de feridas atrav s da forma o de produtos finais de glica o avan ada que induzem a cria o de mol culas inflamat rias (TNF-, IL-1) e dificultam a s ntese de colag nio. Com o n vel elevado de glicose tamb m se alteram a morfologia celular, reduz-se a prolifera o, o tecido de granula o fica com falta de colag nio e h uma diferencia o anormal dos queratin citos. Os hidrog is (HGs) s o redes de pol meros tridimensionais que incham com grandes quantidades de um solvente. Os hidrog is t m uma textura flex vel, borrachosa e macia, assemelhando-se a tecidos humanos com conten o influente como aplica o em feridas. Os hidrog is s o particularmente vantajosos porque podem evitar a perda de gua e a infe o secund ria, absorver os fluidos da ferida e proporcionar uma troca gasosa adequada. Devido estrutura amorfa do hidrogel de goma gelana-quitosano (GGCH).
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Idrogeli fabbricati con apigenina

Idrogeli fabbricati con apigenina

Sushil Kumar Kashaw; Rajesh Shukla; Alok Pal Jain

Edizioni Sapienza
2024
pokkari
La ferita una rottura dell'integrit epiteliale della pelle che deriva da un'aggressione o da un trauma e che pu essere seguita da un'alterazione della struttura e del ruolo del tessuto normale sottostante. stato affermato che l'iperglicemia ha un effetto tossico sulla guarigione delle ferite attraverso la formazione di prodotti finali della glicazione avanzata che inducono la creazione di molecole infiammatorie (TNF-, IL-1) e ostacolano la sintesi del collagene. Con l'alto livello di glucosio si modificano anche la morfologia cellulare, si riduce la proliferazione, il tessuto di granulazione privo di collagene e la differenziazione dei cheratinociti anormale. Gli idrogel (HG) sono reti di polimeri tridimensionali che si gonfiano grazie a enormi quantit di solvente. Gli idrogel hanno una consistenza flessibile, gommosa e morbida, simile a quella dei tessuti umani, con un'applicazione influente sulle ferite. Gli idrogel sono particolarmente vantaggiosi perch possono prevenire la perdita di acqua e le infezioni secondarie, assorbire i fluidi della ferita e fornire un adeguato scambio gassoso. Grazie alla struttura amorfa della gomma gellano-chitosano (GGCH), gli idrogel (HG) possono assorbire acqua fino al 99% del proprio peso.
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Hydrogels fabriqués à base d'apigénine

Hydrogels fabriqués à base d'apigénine

Sushil Kumar Kashaw; Rajesh Shukla; Alok Pal Jain

Editions Notre Savoir
2024
pokkari
La plaie est une rupture de l'int grit pith liale de la peau qui r sulte d'une agression ou d'un traumatisme et qui peut tre suivie d'une perturbation de la structure et du r le du tissu normal sous-jacent. Il a t d montr que l'hyperglyc mie a un effet toxique sur la cicatrisation des plaies par la formation de produits finaux de glycation avanc e qui favorisent la cr ation de mol cules inflammatoires (TNF-, IL-1) et entravent la synth se du collag ne. Le taux lev de glucose entra ne galement des modifications de la morphologie cellulaire, une r duction de la prolif ration, un manque de collag ne dans le tissu de granulation et une diff renciation anormale des k ratinocytes. Les hydrogels (HG) sont des r seaux de polym res tridimensionnels gonfl s par d' normes quantit s de solvant. Les hydrogels ont une texture souple, caoutchouteuse et molle qui ressemble celle des tissus humains, ce qui leur conf re une grande influence dans l'application sur les plaies. Les hydrogels sont particuli rement avantageux car ils peuvent emp cher la perte d'eau et l'infection secondaire, absorber les fluides de la plaie et fournir un change gazeux ad quat. En raison de la structure amorphe de la gomme gellane et du chitosane (GGCH), les hydrogels peuvent absorber de l'eau jusqu' 99 % de leur propre poids.
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Mit Apigenin hergestellte Hydrogele

Mit Apigenin hergestellte Hydrogele

Sushil Kumar Kashaw; Rajesh Shukla; Alok Pal Jain

Verlag Unser Wissen
2024
pokkari
Eine Wunde ist eine Verletzung der epithelialen Integrit t der Haut, die auf eine Aggression oder ein Trauma zur ckzuf hren ist und durch eine St rung der Struktur und der Funktion des darunter liegenden normalen Gewebes hervorgerufen werden kann. Es wurde festgestellt, dass Hyperglyk mie eine toxische Wirkung auf die Wundheilung durch die Bildung von fortgeschrittenen Glykierungsendprodukten hat, die die Bildung von Entz ndungsmolek len (TNF-, IL-1) f rdern und die Kollagensynthese behindern. Mit dem hohen Glukosespiegel ver ndern sich auch die Zellmorphologie, die Proliferation nimmt ab, dem Granulationsgewebe mangelt es an Kollagen und die Differenzierung der Keratinozyten ist gest rt. Hydrogele (HGs) sind Netzwerke aus dreidimensionalen Polymeren, die durch gro e Mengen eines L sungsmittels aufgequollen sind. Die HGs haben eine flexible, gummiartige und weiche Textur, die dem menschlichen Gewebe hnelt und sich hervorragend f r die Wundbehandlung eignet. Hydrogele sind besonders vorteilhaft, weil sie Wasserverluste und Sekund rinfektionen verhindern, Wundfl ssigkeiten absorbieren und f r einen ausreichenden Gasaustausch sorgen k nnen. Aufgrund der amorphen Struktur von Gellan-Gummi-Chitosan (GGCH) k nnen Hydrogele (HGs) bis zu 99 % ihres Eigengewichts an Wasser aufnehmen.
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Studien Über Gastrointestinale Nematoden Bei Ziegen

Studien Über Gastrointestinale Nematoden Bei Ziegen

Rupesh Chaurasiya; Pooja Dixit; Alok Kumar Dixit

Verlag Unser Wissen
2024
pokkari
Dieses Buch enth lt aktualisierte Informationen ber die Pr valenz verschiedener gastrointestinaler Parasiten bei Ziegen sowie eine Diskussion ber Risikofaktoren im Zusammenhang mit diesen Parasiten. Dieses Buch enth lt auch Informationen ber die therapeutische Wirksamkeit der drei g ngigen Anthelminthika Fenbendazol, Closantel und Ivermectin gegen gastrointestinale Nematoden. Dieses Buch enth lt auch einen berblick ber Pr valenzstudien an Ziegen und die Auswirkungen von gastrointestinalen Parasiten auf h matobiochemische Parameter bei Ziegen. Dieses Buch wird f r Ziegenpraktiker, Forscher und Studenten hilfreich sein.
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Estudos Sobre Nemátodos Gastrointestinais Em Caprinos

Estudos Sobre Nemátodos Gastrointestinais Em Caprinos

Rupesh Chaurasiya; Pooja Dixit; Alok Kumar Dixit

Edicoes Nosso Conhecimento
2024
pokkari
Este livro cont m uma informa o actualizada sobre a preval ncia de diferentes parasitas gastrointestinais em caprinos, juntamente com uma discuss o sobre os factores de risco associados a estes parasitas. Este livro inclui tamb m informa es sobre a efic cia terap utica de tr s anti-helm nticos comuns, o fenbendazol, o closantel e a ivermectina, sobre os nem todos gastrointestinais. Este livro inclui ainda uma revis o dos estudos de preval ncia efectuados em caprinos e do efeito dos parasitas gastrointestinais nos par metros hematobioqu micos dos caprinos. Este livro ser til para profissionais, investigadores e estudantes do sector caprino.
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Studi Sui Nematodi Gastrointestinali Nelle Capre

Studi Sui Nematodi Gastrointestinali Nelle Capre

Rupesh Chaurasiya; Pooja Dixit; Alok Kumar Dixit

Edizioni Sapienza
2024
pokkari
Questo libro contiene informazioni aggiornate sulla prevalenza di diversi parassiti gastrointestinali nelle capre e una discussione sui fattori di rischio associati a questi parassiti. Il libro contiene anche informazioni sull'efficacia terapeutica dei tre comuni antielmintici Fenbendazolo, Closantel e Ivermectina sui nematodi gastrointestinali. Il libro include anche una rassegna degli studi di prevalenza condotti sulle capre e degli effetti dei parassiti gastrointestinali sui parametri ematobiochimici delle capre. Questo libro sar utile per gli operatori del settore caprino, i ricercatori e gli studenti.
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Études Sur Les Nématodes Gastro-Intestinaux Chez Les Chèvres

Études Sur Les Nématodes Gastro-Intestinaux Chez Les Chèvres

Rupesh Chaurasiya; Pooja Dixit; Alok Kumar Dixit

Editions Notre Savoir
2024
pokkari
Ce livre contient des informations actualis es sur la pr valence de diff rents parasites gastro-intestinaux chez les ch vres, ainsi qu'une discussion sur les facteurs de risque associ s ces parasites. Il contient galement des informations sur l'efficacit th rapeutique de trois anthelminthiques courants, le fenbendazole, le closantel et l'ivermectine, sur les n matodes gastro-intestinaux. Ce livre comprend galement une revue des tudes de pr valence r alis es sur les ch vres et l'effet des parasites gastro-intestinaux sur les param tres h matobiochimiques chez les ch vres. Ce livre sera utile aux praticiens, aux chercheurs et aux tudiants en caprins.
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Plant Diseases

Plant Diseases

J.P. Rai; Alok K.Singh

New India Publishing Agency
2014
nidottu
The advancement of chemical management techniques for plant diseases has led to a corresponding increase in problems related to pesticide application in agriculture. Improper identification of plant diseases is a contributing factor to this issue, as it can result in the use of inappropriate chemicals in excessive amounts. Therefore, it is necessary to educate those involved in agricultural education, extension, and practice on the proper characterization of plant diseases and the most effective management strategies for each disease. Students, extension workers, and farmers are the primary clients who must be informed about the correct identification methods and management of specific plant diseases.This book is designed to meet the needs of undergraduate and postgraduate students of agriculture and biosciences, extension workers, and progressive farmers who have received education. Its purpose is to assist these individuals in accurately identifying economically significant plant diseases and implementing integrated management strategies for each disease. Additionally, the book may serve as a guide for professionals in the field of plant disease management, providing information on the identification and management of plant diseases with minimal resource requirements.
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Plant Diseases

Plant Diseases

J.P. Rai; Alok K.Singh

New India Publishing Agency
2014
sidottu
The field of chemical management of plant diseases has seen significant advancements in recent times, which has unfortunately resulted in an increase in problems related to pesticide application in agriculture. One of the contributing factors to this issue is the improper identification of plant diseases, which can lead to the use of inappropriate chemicals in excessive amounts. In light of this, it is crucial to educate those involved in agricultural education, extension, and practice on the proper identification of plant diseases and the most effective management strategies for each disease. Students, extension workers, and farmers are the primary clients who must be equipped with the necessary information on identification methods and disease management.This book has been designed to meet the needs of undergraduate and postgraduate students of agriculture and biosciences, extension workers, and progressive farmers who have received formal education. It aims to assist these individuals in accurately identifying economically significant plant diseases and implementing integrated management strategies for each disease. Additionally, this book can serve as a practical guide for professionals in the field of plant disease management, providing guidance on disease identification and management with minimal resource requirements.
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Fundamentals of Automata Theory and Compiler Construction

Fundamentals of Automata Theory and Compiler Construction

Narendra Kumar; Santosh Kumar Sharma; Alok Agarwal; Er. Mayank Kumar Jain

TechSar Pvt. Ltd
2022
nidottu
This book divided in eleven chapters, in the first chapter describes basics of a compiler, its definition and its types. It also includes the need of a compiler. The second chapter deals with phases of compiler, frontend and book end of compiler, single pass and multiphase compiler; Chapter three covers role of logical analyzer, description of tokens, automata, the fourth chapter presents syntax analyzer, grammar, LMD, RMD, passing techniques. Fifth chapter gives syntax directed translation, syntax tree, attributes such as synthesis and inherited. Chapter six deals with type checking, its definition, dynamic type checking and equivalence of it, function overloading and parameter passing. Chapter seven covers run time environment storage allocation techniques, symbol table. Chapter eight presents intermediate code generators, techniques of ICG, conversion. Chapter nine deals with code generation, basic blocks, flow graph, peephole optimization while chapter ten is on code optimization, that contains optimization of basic blocks, reducible flow graph, data flow analysis and global analysis. Chapter eleven one-pass compiler, compiler, its structure, STD rules and passing are described.
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IAP Recent Advances in Pedatrics - 1

IAP Recent Advances in Pedatrics - 1

A Parthasarathy; PSN Menon; Alok Gupta; MKC Nair; Piyush Gupta

Jaypee Brothers Medical Publishers
2020
nidottu
This book has been brought out as a “Pediatric Digest” like Pediatric Clinics of North America and Best Clinical Practice Research Series, consisting of 568 pages incorporating 28 chapters. Each major subspecialty is covered in this book by at least one chapter on a selected topic. The write-up provides the most recent review on the topic with clinical practice points by chosen Indian Pediatric Experts in the field.IAP Recent Advances in Pediatrics is the New Baby of the Indian Academy of Pediatrics (IAP).Covers the perinatal age to adolescence, is designed to be a regular annual release during PEDICON every year from 2020.Experts of international and national repute have put in the best systems and organs in this creation.State-of-the-art book has been brought out as a ""Pediatric Digest"" like Pediatric Clinics of North America and Best Clinical Practice Research Series with a volume every coming year.Consists of 568 pages incorporating 28 chapters.Covers each major subspecialty by at least one chapter on a selected topic.Provides the most recent review on the topic with clinical practice points by chosen Indian pediatric experts in the field.
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