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854 tulosta hakusanalla Corelli Marie Corelli

Introduction to Modeling in Physiology and Medicine

Introduction to Modeling in Physiology and Medicine

Claudio Cobelli; Ewart R. Carson

Academic Press Inc
2019
nidottu
Introduction to Modeling in Physiology and Medicine, Second Edition, develops a clear understanding of the fundamental principles of good modeling methodology. Sections show how to create valid mathematical models that are fit for a range of purposes. These models are supported by detailed explanation, extensive case studies, examples and applications. This updated edition includes clearer guidance on the mathematical prerequisites needed to achieve the maximum benefit from the material, a greater detail regarding basic approaches to modeling, and discussions on non-linear and stochastic modeling. The range of case study material has been substantially extended, with examples drawn from recent research experience. Key examples include a cellular model of insulin secretion and its extension to the whole-body level, a model of insulin action during a meal/oral glucose tolerance test, a large-scale simulation model of type 1 diabetes and its use in in silico clinical trials and drug trials.
La casa di Laila

La casa di Laila

Raffaele Colelli

Lulu.com
2017
pokkari
la casa di Laila la storia di profondi sentimenti, intrecciati tra loro come le strade e i destini dei personaggi.Laila protagonista del libro, una ragazza dal cuore puro, un bocciolo di rosa nata in seguito alla tragica morte della madre Mila, vive accanto a sua nonna Irina, da qualche tempo malata.Tiene sempre in mente i valori di lealt , rispetto e amore per il prossimo che il suo caro nonno Boris, allevatore di cavalli di razza bulgara orientale, li ha trasmesso.Le sorti della grande fattoria in cui cresciuta, con gli inseparabili Jar e Jarina, a nord della Valle Delle Rose, a cinquanta km da Plovdiv, sono nelle sue mani.Quando che non pi possibile ormai occuparsi della vendita dei cavalli, Laila decide di organizzare una scuola di ippoterapia e, grazie al prezioso aiuto di zia Wanda, trova il tempo necessario di proseguire gli studi in medicina.La zia decisa a riscattarsi da una vita di miserie e violenze, ma suo marito Costinel e suo figlio Dragu Barbu riusciranno a scovarla e prenderanno l'anima di Laila.
Tracer Kinetics in Biomedical Research

Tracer Kinetics in Biomedical Research

Claudio Cobelli; David Foster; Gianna Toffolo

Kluwer Academic/Plenum Publishers
2001
sidottu
The use of mathematical modeling te chniques in biomedical research is playing an increasingly important role aso ne seeks tounderstand the physiopathology of disease processes. This includes not only understand ing mechanisms ofphysiological processes, but diagnosis and treatment. In addition, its introduction in the study of genomics andproteomics is key in understanding the functional ch aracteristics of gene expression and protein assembly and secretion. Finally, with the increasing com plexity and associated cost of drug development, modeling techniques are being used to streamline the process. We have workedin c lose collaboration with colleagues in biomedical and pharmaceutical research for a number of years applying and refining mathematical modeling techniques to avariety o f problems. In addition, we haveworked incollaboration with colleagues in applied m athematics and statistics to develop new algorithms to solve new setsof problems as theyemerge ino ur research efforts. Finally, we have worked with colleagues in computer sciencet o develop new software tools that bring the power of mathematical modeling to a broad research community. This books brings together mucho f what we have learned over the years, and presents the material in a format that should be accessible both to the novice reader and those desiring more detailed information about specific techniques.
Rome and Environs

Rome and Environs

Filippo Coarelli

University of California Press
2014
pokkari
This superb guide brings the work of Filippo Coarelli, one of the most widely published and well-known scholars of Roman topography, archeology and art, to a broad English-language audience. Conveniently organized by walking tours and illustrated throughout with clear maps, drawings, and plans, Rome and Environs: An Archaeological Guide covers all of the major, and an unparalleled number of minor, ancient sites in the city, and, unlike most other guides of Rome, includes major and many minor sites within easy reach of the city, such as Ostia Antica, Palestrina, Tivoli, and the many areas of interest along the ancient Roman roads. An essential resource for tourists interested in a deeper understanding of Rome's classical remains, it is also the ideal book for students and scholars approaching the ancient history of one of the world's most fascinating cities. * Covers all the major sites including the Capitoline, the Roman Forum, the Imperial Fora, the Palatine Hill, the Valley of the Colosseum, the Esquiline, the Caelian, the Quirinal, and the Campus Martius. * Discusses important clusters of sites-one on the area surrounding Circus Maximus and the other in the vicinity of the Trastevere, including the Aventine and the Vatican. * Covers the history and development of the city walls and aqueducts. * Follows major highways leading outside of the city to important and fascinating sites in the periphery of Rome. * Features 189 maps, drawings, and diagrams, and an appendix on building materials and techniques. * Includes an updated and expanded bibliography for students and scholars of Ancient Rome.
Carnations

Carnations

Anthony Carelli

Princeton University Press
2011
pokkari
In Anthony Carelli's remarkable debut, Carnations, the poems attempt to reanimate dead metaphors as blossoms: wild and lovely but also fleeting, mortal, and averse to the touch. Here, the poems are carnations, not only flowers, but also body-making words. Nodding to influences as varied as George Herbert, Francis Ponge, Fernando Pessoa, and D. H. Lawrence, Carelli asserts that the poet's materials--words, objects, phenomena--are sacred, wilting in the moment, yet perennially renewed. Often taking titles from a biblical vocabulary, Carnations reminds us that unremarkable places and events--a game of Frisbee in a winter park, workers stacking panes in a glass factory, or the daily opening of a cafe--can, in a blink, be new. A short walk home is briefly transformed into a cathedral, and the work-worn body becomes a dancer, a prophet, a muse. ______ From Carnations: THE PROPHETS Anthony Carelli A river. And if not the river nearby, then a dream of a river. Nothing happens that doesn't happen along a river, however humble the water may be. Take Rowan Creek, the trickle struggling to lug its mirroring across Poynette, wherein, suspended, so gentle and shallow, I learned to walk, bobbing at my father's knees. Later, whenever we tried to meander on our inner tubes, we'd get lodged on the bottom. Seth, remember, no matter how we'd kick and shove off, we'd just get lodged again? At most an afternoon would carry us a hundred feet toward the willows. We'd piss ourselves on purpose just to feel the spirits of our warmth haloing out. And once, two bald men on the footbridge, bowing in the sky, stared down at us without a word.
The Privatized State

The Privatized State

Chiara Cordelli

PRINCETON UNIVERSITY PRESS
2020
sidottu
Why government outsourcing of public powers is making us less freeMany governmental functions today—from the management of prisons and welfare offices to warfare and financial regulation—are outsourced to private entities. Education and health care are funded in part through private philanthropy rather than taxation. Can a privatized government rule legitimately? The Privatized State argues that it cannot.In this boldly provocative book, Chiara Cordelli argues that privatization constitutes a regression to a precivil condition—what philosophers centuries ago called "a state of nature." Developing a compelling case for the democratic state and its administrative apparatus, she shows how privatization reproduces the very same defects that Enlightenment thinkers attributed to the precivil condition, and which only properly constituted political institutions can overcome—defects such as provisional justice, undue dependence, and unfreedom. Cordelli advocates for constitutional limits on privatization and a more democratic system of public administration, and lays out the central responsibilities of private actors in contexts where governance is already extensively privatized. Charting a way forward, she presents a new conceptual account of political representation and novel philosophical theories of democratic authority and legitimate lawmaking.The Privatized State shows how privatization undermines the very reason political institutions exist in the first place, and advocates for a new way of administering public affairs that is more democratic and just.
The Privatized State

The Privatized State

Chiara Cordelli

PRINCETON UNIVERSITY PRESS
2022
pokkari
Why government outsourcing of public powers is making us less freeMany governmental functions today—from the management of prisons and welfare offices to warfare and financial regulation—are outsourced to private entities. Education and health care are funded in part through private philanthropy rather than taxation. Can a privatized government rule legitimately? The Privatized State argues that it cannot.In this boldly provocative book, Chiara Cordelli argues that privatization constitutes a regression to a precivil condition—what philosophers centuries ago called "a state of nature." Developing a compelling case for the democratic state and its administrative apparatus, she shows how privatization reproduces the very same defects that Enlightenment thinkers attributed to the precivil condition, and which only properly constituted political institutions can overcome—defects such as provisional justice, undue dependence, and unfreedom. Cordelli advocates for constitutional limits on privatization and a more democratic system of public administration, and lays out the central responsibilities of private actors in contexts where governance is already extensively privatized. Charting a way forward, she presents a new conceptual account of political representation and novel philosophical theories of democratic authority and legitimate lawmaking.The Privatized State shows how privatization undermines the very reason political institutions exist in the first place, and advocates for a new way of administering public affairs that is more democratic and just.
The New World

The New World

Anthony Carelli

Princeton University Press
2021
pokkari
From an “uncommonly fluent” and “rewarding” poet (The Observer), a collection of miniature epics that asks: can grace be found amid disarray?The New World, Anthony Carelli’s new collection of poems, is an American travelogue that unfolds in a series of darkly comic episodes, with allusions to Dante as a thread throughout. In these epics in miniature, we meet a pilgrim-poet as he awaits the arrival of his child, a would-be Columbus, on the shores of a land “disenstoried” by explorers present and past. It’s a land and a people largely lost in mindscapes and mythscapes, haunted by sketchy aspirational visions, misbegotten misremembering, and emptiness. Nonetheless, the poet steps out to the shore to sing for the child—and reader—to do what Columbus never did: “land gently. / And listen and / listen and listen / and stay.” Constantly unsettling the rhetoric of inherited forms, the poet shaping these poems is always bound to the pilgrim, who cannot pretend to dissolve our purgatories but can only invite us—as a latter-day Virgil would—deeper into the uncanny encounters that encircle us. From an Arizona nursing home and a grandmother's memory of a stolen golden Schwinn in the occupied Philippines, to a tale of road-tripping west through Pennsylvania as sunrise transpires in the wrong sky, The New World opens strange spaces for us to re-see, lament, and re-sing the stories we tell.
The New World

The New World

Anthony Carelli

PRINCETON UNIVERSITY PRESS
2021
sidottu
From an “uncommonly fluent” and “rewarding” poet (The Observer), a collection of miniature epics that asks: can grace be found amid disarray?The New World, Anthony Carelli’s new collection of poems, is an American travelogue that unfolds in a series of darkly comic episodes, with allusions to Dante as a thread throughout. In these epics in miniature, we meet a pilgrim-poet as he awaits the arrival of his child, a would-be Columbus, on the shores of a land “disenstoried” by explorers present and past. It’s a land and a people largely lost in mindscapes and mythscapes, haunted by sketchy aspirational visions, misbegotten misremembering, and emptiness. Nonetheless, the poet steps out to the shore to sing for the child—and reader—to do what Columbus never did: “land gently. / And listen and / listen and listen / and stay.” Constantly unsettling the rhetoric of inherited forms, the poet shaping these poems is always bound to the pilgrim, who cannot pretend to dissolve our purgatories but can only invite us—as a latter-day Virgil would—deeper into the uncanny encounters that encircle us. From an Arizona nursing home and a grandmother's memory of a stolen golden Schwinn in the occupied Philippines, to a tale of road-tripping west through Pennsylvania as sunrise transpires in the wrong sky, The New World opens strange spaces for us to re-see, lament, and re-sing the stories we tell.