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1000 tulosta hakusanalla Brian D. Meeks

Design and Analysis of Non-Inferiority Trials

Design and Analysis of Non-Inferiority Trials

Mark D. Rothmann; Brian L. Wiens; Ivan S.F. Chan

Chapman Hall/CRC
2011
sidottu
The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Using examples from real clinical trials, Design and Analysis of Non-Inferiority Trials brings together this body of research and confronts the issues involved in the design of a non-inferiority trial. Each chapter begins with a non-technical introduction, making the text easily understood by those without prior knowledge of this type of trial. Topics covered include: A variety of issues of non-inferiority trials, including multiple comparisons, missing data, analysis population, the use of safety margins, the internal consistency of non-inferiority inference, the use of surrogate endpoints, trial monitoring, and equivalence trialsSpecific issues and analysis methods when the data are binary, continuous, and time-to-eventThe history of non-inferiority trials and the design and conduct considerations for a non-inferiority trialThe strength of evidence of an efficacy finding and how to evaluate the effect size of an active control therapyA comprehensive discussion on the purpose and issues involved with non-inferiority trials, Design and Analysis of Non-inferiority Trials will assist current and future scientists and statisticians on the optimal design of non-inferiority trials and in assessing the quality of non-inferiority comparisons done in practice.
Lone Wolf Terrorism

Lone Wolf Terrorism

Jeffrey D. Simon; Brian Michael Jenkins

PROMETHEUS BOOKS
2016
pokkari
From Anders Breivik in Norway, who murdered scores of young people in a bombing and mass-shooting attack, to Omar Mateen, the Orlando killer who perpetrated the worst mass shooting in American history, lone wolves have demonstrated that they can be as dangerous as organized terrorist groups. Who are these terrorists and what can be done about them? An internationally renowned terrorism expert presents the first comprehensive treatment of this important issue. After delving into the diversity in motivations and backgrounds of lone wolf terrorists, Simon makes the following key points about this growing threat: lone wolves have proven to be more creative and dangerous than many terrorist groups; lone wolves are not just Islamist extremists but can be found among all types of political and religious ideologies; the Internet has provided the perfect breeding ground for isolated individuals with terrorist tendencies, but it may also prove to be their undoing; there are few women in this category, but this is likely to change in the coming years; and the common perception that nothing can be done about lone wolves is wrong. In fact, innovative strategies and policies can be developed to both prevent and respond to this type of terrorism. Drawing on his more than twenty-five years of experience studying terrorism, Simon has produced an insightful book that is essential reading for anyone concerned about the potential terrorist threats from violence-prone individuals in our midst.This paperback edition contains a new preface by the author, which reviews lone-wolf incidents since the publication of the original edition.
Blind Faith

Blind Faith

Brian S. Neumann Ph. D.

978-164826209-8
2020
nidottu
This book is about real-life Alice who, in blind faith, follows a White Rabbit down the proverbial rabbit-hole that leads her to a Wonderland, where, among other things, she ends up at a tea-party, hosted by a Mad Hatter and March Hare who incessantly fill her head with non-sensical, hallucinatory riddles and tales. As she relentlessly continues trying to follow the White Rabbit, Alice makes acquaintances who give her strange advice and misleading directions until, finally, she ends up on trial for crimes that-in this real-life version-she really did commit. This is the sad, sobering but true account of Seventh-day Adventist's and other entities who have chosen to follow a religious or political thought-leader down the rabbit-hole of specious dogmas and practices.
All You Need Is . . .: Remembering Who You Really Are

All You Need Is . . .: Remembering Who You Really Are

Brian M. McCay Ph. D.

Createspace Independent Publishing Platform
2018
nidottu
This book is about you. The intent is to ignite your inner remembrance of who you really are. The truth is, Love is all there is and as a piece of God, you are an infinite expression of that Love.My stories show how paying attention offers opportunities to remember who you really are. Hopefully you can relate my stories to those of your life and the lives of the ones you love. The intent is to help you see the service in all you experience in life. The book asks you to consider: -You are so much more than you have been led to believe-God is inside of you (you are Source energy)-You are responsible for your creations and personal reality-You co-create synchronicities to execute your life plan-You have free choice-There are no accidents-You planned to be here during this very special time on Earth-The New Energy is transforming our consciousness to one of Love-Striking your match lights the way for others-All you need is ... Love
Suetonius: The Flavian Emperors

Suetonius: The Flavian Emperors

Brian W. Jones; R.D. Milns

Bristol Classical Press
2002
nidottu
Nero's suicide in AD 68 was followed by a disastrous civil war that left the empire in a parlous state and saw the demise, in quick succession, of another three emperors (Galba, Otho and Vitellius). Normality returned with Vespasian and his sons, Titus and Domitian who ruled from 69 to 96. They changed the face of Rome, with massive public works such as the Flavian amphitheatre (later called the Colosseum) and the palace-complex on the Palatine, which provided much-needed employment whilst at the same time enhancing the city's status as the capital of the Mediterranean. The most detailed account of the new dynasty and its achievements is provided by Suetonius. What he has to say about these three Flavians constitutes the best source we have for the period. This edition of the three "Lives" includes a new translation, a general introduction to Suetonius and a detailed commentary that concentrates on the social and political history behind each life.
Black Cotton

Black Cotton

Patrick D. Foreman; Brian Hawkins

Scout Comics
2022
nidottu
Black Cotton is an ongoing comic book series set in an alternate reality that revolves around an exorbitantly wealthy black family, the Cottons, created by Brian Hawkins and Patrick Foreman, Illustrated by Marco Perugini, and published by Scout Comics. Set in an alternate reality where the social order of "white" and "black" is reversed, when it comes to social standing and class, the Cottons are at the top of the food chain, part of the One Percent, and are seemingly untouchable. However, that all changes when Zion, their police officer son, who decided to not follow in the footsteps of his father and matriculate towards running the family business, is involved in the shooting of a minority white woman. In a reality similar to our own, social tensions are already high, race is a hot topic, and the call for equality between white and black is aggressively being pursued. Thus, Zion Cotton shooting Elizabeth Nightingale, a twenty-something college student on scholarship for track, ignites their city in a fury of protests and a call for action against racial injustice. Led by the family's patriarch, Elijah Cotton, and matriarch, Jaleesa Cotton, the Cottons are thrusted into the middle of a highly controversial predicament and immediately attempt to use their wealth, prestige, and power to remedy the problem. However, while the youngest Cotton, Xavier, a teenager, actively protests the social injustices with his friends, the middle child, Qia Cotton, the acting CCO of Black Cotton Ventures, a multi-billion dollar manufacturing conglomerate, does damage control for her wayward brother. Ultimately, more division is created between both families as the Nightingales, unwilling to be assuaged, seek justice for Elizabeth, their daughter, who survived. "Black Cotton is a comic, but it's also a mindset that's being explored in a comic."
Honey Bee Biology

Honey Bee Biology

Brian R. Johnson; Thomas D. Seeley

PRINCETON UNIVERSITY PRESS
2026
pokkari
The most comprehensive and up-to-date general reference book on honey bee biology Honey bees are marvelously charismatic organisms with a long history of interaction with humans. They are vital to agriculture and serve as a model system for many basic questions in biology. This authoritative book provides an essential overview of honey bee biology, bringing established topics up to date while incorporating emerging areas of inquiry. Honey Bee Biology covers everything from molecular genetics, development, and physiology to neurobiology, behavior, and pollination biology. Placing special attention on the important role of bees as pollinators in agricultural ecosystems, it incorporates the latest findings on pesticides, parasites, and pathogens. This incisive and wide-ranging book also sheds vital light on the possible causes of colony collapse disorder and the devastating honey bee losses we are witnessing today. The study of honey bees has greatly expanded in recent years and there is more interest in these marvelous creatures than ever before. Honey Bee Biology is the first up-to-date general reference of its kind published in decades. It is a must-have resource for social insect biologists, scientifically savvy beekeepers, and any scientist interested in bees as a model system.
High Resolution X-Ray Diffractometry And Topography

High Resolution X-Ray Diffractometry And Topography

D.K. Bowen; Brian K. Tanner

CRC Press
2019
nidottu
The study and application of electronic materials has created an increasing demand for sophisticated and reliable techniques for examining and characterizing these materials. This comprehensive book looks at the area of x-ray diffraction and the modern techniques available for deployment in research, development, and production. It provides the theoretical and practical background for applying these techniques in scientific and industrial materials characterization. The main aim of the book is to map the theoretical and practical background necessary to the study of single crystal materials by means of high-resolution x-ray diffraction and topography. It combines mathematical formalisms with graphical explanations and hands-on practical advice for interpreting data.
Handbook of Machining with Grinding Wheels

Handbook of Machining with Grinding Wheels

Ioan D. Marinescu; Mike P. Hitchiner; Eckart Uhlmann; W. Brian Rowe; Ichiro Inasaki

CRC Press
2019
nidottu
Grinding is a crucial technology that employs specific abrasive processes for the fabrication of advanced products and surfaces. Handbook of Machining with Grinding Wheels, Second Edition highlights important industry developments that can lead to improved part quality, higher productivity, and lower costs. Divided into two parts, the book begins with an explanation of grinding behavior and ends with a focus on new and emerging industrial applications. While the first edition focused on the basics of abrasive machining technology and presented a unified approach to machining with grinding wheels, the second edition ties in the continued need for traditional processes in conjunction with the latest applications. This book highlights new research topics that include: nanotechnology, alternative energy, and additive manufacturing, compares related approaches, and provides numerous references throughout the book.New in the Second Edition: Contains the latest information on abrasives, bonds, and dressingUpdates classic stability lobes for grindingIntroduces a new method for tracking dynamic instability in centerless grindingProvides a section in the chapter on ultrasonic-assisted grinding, which contains recent work on modelling of the processAdds material on fluid cooling Presents experimental results for in-process feedback to the grinding process Includes new examples on grinding machine technology (particularly for dressing) A single source reference covering every aspect of the grinding process, Handbook of Machining with Grinding Wheels functions as a definitive guide to grinding technology for both practicing engineers and students studying graduate-level courses (such as abrasive machining; grinding R&D; metal removal processes; machining of brittle materials; and principles of
Stream Hydrology

Stream Hydrology

Nancy D. Gordon; Thomas A. McMahon; Brian L. Finlayson; Christopher J. Gippel; Rory J. Nathan

John Wiley Sons Inc
2004
sidottu
Water plays an important part in today's environmental concerns. Since the publication of the first edition there have been rapid developments in the application of hydrology, geomorphology and ecology to stream management. In particular, growth has occurred in the areas of stream rehabilitation and the evaluation of environmental flow needs. The concept of stream health has been adopted as a way of assessing stream resources and setting management goals. Stream Hydrology: An Introduction for Ecologists Second Edition documents recent research and practice in these areas. Chapters provide information on sampling, field techniques, stream analysis, the hydrodynamics of moving water, channel form, sediment transport and commonly used statistical methods such as flow duration and flood frequency analysis. Methods are presented from engineering hydrology, fluvial geomorphology and hydraulics with examples of their biological implications. This book demonstrates how these fields are linked and utilised in modern, scientific river management. *Emphasis on applications, from collecting and analysing field measurements to using data and tools in stream management. *Updated to include new sections on environmental flows, rehabilitation, measuring stream health and stream classification. *Critical reviews of the successes and failures of implementation. *Revised and updated windows-based software. This book is essential reading for 2nd/3rd year undergraduates and postgraduates of hydrology, stream ecology and fisheries science in Departments of Physical Geography, Biology, Environmental Science, Landscape Ecology, Environmental Engineering and Limnology. It would be valuable reading for professionals working in stream ecology, fisheries science and habitat management, environmental consultants and engineers.
Stream Hydrology

Stream Hydrology

Nancy D. Gordon; Thomas A. McMahon; Brian L. Finlayson; Christopher J. Gippel; Rory J. Nathan

John Wiley Sons Inc
2004
nidottu
Water plays an important part in today's environmental concerns. Since the publication of the first edition there have been rapid developments in the application of hydrology, geomorphology and ecology to stream management. In particular, growth has occurred in the areas of stream rehabilitation and the evaluation of environmental flow needs. The concept of stream health has been adopted as a way of assessing stream resources and setting management goals. Stream Hydrology: An Introduction for Ecologists Second Edition documents recent research and practice in these areas. Chapters provide information on sampling, field techniques, stream analysis, the hydrodynamics of moving water, channel form, sediment transport and commonly used statistical methods such as flow duration and flood frequency analysis. Methods are presented from engineering hydrology, fluvial geomorphology and hydraulics with examples of their biological implications. This book demonstrates how these fields are linked and utilised in modern, scientific river management. * *Emphasis on applications, from collecting and analysing field measurements to using data and tools in stream management. *Updated to include new sections on environmental flows, rehabilitation, measuring stream health and stream classification. *Critical reviews of the successes and failures of implementation. *Revised and updated windows-based software. This book is essential reading for 2nd/3rd year undergraduates and postgraduates of hydrology, stream ecology and fisheries science in Departments of Physical Geography, Biology, Environmental Science, Landscape Ecology, Environmental Engineering and Limnology. It would be valuable reading for professionals working in stream ecology, fisheries science and habitat management, environmental consultants and engineers.
Improving Teaching Effectiveness: Implementation

Improving Teaching Effectiveness: Implementation

Brian M. Stecher; Michael S. Garet; Laura S. Hamilton; Elizabeth D. Steiner; Abby Robyn; Jeffrey Poirier; Deborah Holtzman; Eleanor S. Fulbeck; Jay Chambers; Iliana Brodziak de los Reyes

RAND
2016
pokkari
To improve the U.S. education system through more-effective classroom teaching, in school year 2009 2010, the Bill and Melinda Gates Foundation announced its Intensive Partnerships for Effective Teaching. Researchers from the RAND Corporation and the American Institutes for Research evaluated implementation of key reform elements of the program in three public school districts and four charter management organizations."
X-Ray Metrology in Semiconductor Manufacturing

X-Ray Metrology in Semiconductor Manufacturing

D. Keith Bowen; Brian K. Tanner

CRC Press Inc
2006
sidottu
The scales involved in modern semiconductor manufacturing and microelectronics continue to plunge downward. Effective and accurate characterization of materials with thicknesses below a few nanometers can be achieved using x-rays. While many books are available on the theory behind x-ray metrology (XRM), X-Ray Metrology in Semiconductor Manufacturing is the first book to focus on the practical aspects of the technology and its application in device fabrication and solving new materials problems. Following a general overview of the field, the first section of the book is organized by application and outlines the techniques that are best suited to each. The next section delves into the techniques and theory behind the applications, such as specular x-ray reflectivity, diffraction imaging, and defect mapping. Finally, the third section provides technological details of each technique, answering questions commonly encountered in practice. The authors supply real examples from the semiconductor and magnetic recording industries as well as more than 150 clearly drawn figures to illustrate the discussion. They also summarize the principles and key information about each method with inset boxes found throughout the text. Written by world leaders in the field, X-Ray Metrology in Semiconductor Manufacturing provides real solutions with a focus on accuracy, repeatability, and throughput.
High Resolution X-Ray Diffractometry And Topography

High Resolution X-Ray Diffractometry And Topography

D.K. Bowen; Brian K. Tanner

Taylor Francis Ltd
1998
sidottu
The study and application of electronic materials has created an increasing demand for sophisticated and reliable techniques for examining and characterizing these materials. This comprehensive book looks at the area of x-ray diffraction and the modern techniques available for deployment in research, development, and production. It provides the theoretical and practical background for applying these techniques in scientific and industrial materials characterization. The main aim of the book is to map the theoretical and practical background necessary to the study of single crystal materials by means of high-resolution x-ray diffraction and topography. It combines mathematical formalisms with graphical explanations and hands-on practical advice for interpreting data.
Plastering

Plastering

Brian F. Pegg; W. D. Stagg

Wiley-Blackwell (an imprint of John Wiley Sons Ltd)
2007
nidottu
This book will serve as an excellent text for NVQ plastering students, whilst its encyclopaedic structure enables the experienced plasterer to select information quickly on finer points when faced with an unfamiliar task. Architects and surveyors will welcome it as a guide to the scope of the craft and its materials, and as a reference for conservation work. It provides a thorough introduction to the techniques of modern plastering and a comprehensive treatment of present-day fibrous plasterwork. Also included are full technical details of solid work, and thorough coverage of obsolete practices for the purpose of conservation work. It features working drawings in isometric projection to present a three dimensional picture of specific jobs. The Fourth Edition has been updated to take account of new products and techniques, in particular machine plastering, and changes in health and safety requirements. The sections on Floorlaying, Plasterboard and Internal Plastering have been totally rewritten and all subjects have been checked against Standards. Legislation and regulations have been brought up to date. Published in association with the Plasterers’ Craft Guild.
Evidence-Based Emergency Medicine

Evidence-Based Emergency Medicine

Brian Rowe; Eddy S. Lang; Michael D. Brown; Debra Houry; David H. Newman; Peter C. Wyer

Wiley-Blackwell (an imprint of John Wiley Sons Ltd)
2008
sidottu
Emergency physicians assess and manage a wide variety of problems from patients presenting with a diversity of severities, ranging from mild to severe and life-threatening. They are expected to maintain their competency and expertise in areas where there is rapid knowledge change. Evidence-based Emergency Medicine is the first book of its kind in emergency medicine to tackle the problems practicing physicians encounter in the emergency setting using an evidence-based approach. It summarizes the published evidence available for the diagnosis and treatment of common emergency health care problems in adults. Each chapter contextualizes a topic area using a clinical vignette and generates a series of key clinically important diagnostic and treatment questions. By completing detailed reviews of diagnostic and treatment research, using evidence from systematic reviews, RCTs, and prospective observational studies, the authors provide conclusions and practical recommendations. Focusing primarily on diagnosis in areas where evidence for treatment is well accepted (e.g. DVTs), and treatment in other diseases where diagnosis is not complex (e.g. asthma), this text is written by leading emergency physicians at the forefront of evidence-based medicine. Evidence-based Emergency Medicine is ideal for emergency physicians and trainees, emergency department staff, and family physicians specialising in the acute care of medical and injured patients.
Tribology of Abrasive Machining Processes

Tribology of Abrasive Machining Processes

Ioan D. Marinescu; W. Brian Rowe; Boris Dimitrov; Hitoshi Ohmori

William Andrew Publishing
2012
sidottu
This book draws upon the science of tribology to understand, predict and improve abrasive machining processes. Pulling together information on how abrasives work, the authors, who are renowned experts in abrasive technology, demonstrate how tribology can be applied as a tool to improve abrasive machining processes. Each of the main elements of the abrasive machining system are looked at, and the tribological factors that control the efficiency and quality of the processes are described. Since grinding is by far the most commonly employed abrasive machining process, it is dealt with in particular detail. Solutions are posed to many of the most commonly experienced industrial problems, such as poor accuracy, poor surface quality, rapid wheel wear, vibrations, work-piece burn and high process costs. This practical approach makes this book an essential tool for practicing engineers.