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1000 tulosta hakusanalla Terry Robson

Pharmacology in Drug Discovery

Pharmacology in Drug Discovery

Terry P. Kenakin

Academic Press Inc
2011
nidottu
Pharmacology in Drug Discovery: Understanding Drug Response is designed for all students, recent graduates, and new researchers in the pharmaceutical and biotechnology industries who need to interpret change in physiology induced by a chemical substance. Physiological systems customize chemical signal input to their own needs; therefore the same drug can have different effects in different physiological systems. The field of pharmacology is unique in that it furnishes the tools to analyze these different behaviors and traces them to their root cause. This enables predictions of drug behavior to be made in all systems, an invaluable tool for drug discovery because almost all drugs are developed in test systems far removed from the therapeutic one. This valuable resource provides simple explanations of the ways in which biological systems use basic biochemical mechanisms to produce fine chemical control of physiology, allowing for more informed predictions of drug effects in all systems and forming the basis of the drug-discovery process. Chapters follow a logical progression on how to characterize the pharmacology of any given molecule, and include important terminology, chapter summaries, references, and review questions to aid the reader in understanding and retention of the material.
A Pharmacology Primer

A Pharmacology Primer

Terry P. Kenakin

Academic Press Inc
2014
sidottu
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, 4th Edition features the latest ideas and research about the application of pharmacology to the process of drug discovery to equip readers with a deeper understanding of the complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This edition has been thoroughly revised to include material on data-driven drug discovery, biased signaling, structure-based drug design, drug activity screening, drug development (including pharmacokinetics and safety Pharmacology), and much more. With more color illustrations, examples, and exercises throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery, or pharmacologic research.
Pharmacology in Drug Discovery and Development

Pharmacology in Drug Discovery and Development

Terry P. Kenakin

Academic Press Inc
2016
nidottu
Pharmacology in Drug Discovery and Development: Understanding Drug Response, Second Edition, is an introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. The concepts discussed in this book allow for the application of more predictive pharmacological procedures aimed at increasing therapeutic efficacy that will lead to more successful drug development. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization. This edition has been fully revised to address the latest advances and research related to real time kinetic assays, pluridimensional efficacy, signaling bias, irreversible and chemical antagonism, allosterically-induced bias, pharmacokinetics and safety, target and pathway validation, and much more. With numerous valuable chapter summaries, detailed references, practical examples and case studies throughout, Dr. Kenakin successfully navigates a highly complex subject, making it accessible for students, professors, and new researchers working in pharmacology and drug discovery.
A Pharmacology Primer

A Pharmacology Primer

Terry P. Kenakin

Academic Press Inc
2018
nidottu
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research.
Assessing Learners with Special Needs

Assessing Learners with Special Needs

Terry Overton

PEARSON EDUCATION (US)
2022
irtolehti
A practical, applied approach to assessing learners with special needs from early childhood through transition Assessing Learners with Special Needs: An Applied Approach, 8/e provides readers with a practical, step-by-step approach to learning about the complex procedures of the assessment process. This new edition provides a new presentation format and a new format for assessing student mastery of material through interactive learning activities. The Enhanced Pearson eText features embedded video, assessments, and exercises.
Assessing Learners with Special Needs

Assessing Learners with Special Needs

Terry Overton

Pearson
2015
lisenssiavain
An applied approach to assessing learners with special needs from early childhood through transition.Assessing Learners with Special Needs provides a practical, step-by-step approach to assessing students with learning challenges from early childhood through transition. This hands-on guide presents a clear map for assessing student mastery of material through interactive learning activities. For undergraduate and graduate courses in Special Education Assessment. Pearson eText is an easy-to-use digital textbook that you can purchase on your own or instructors can assign for their course. The mobile app lets you keep on learning, no matter where your day takes you, even offline. You can also add highlights, bookmarks, and notes in your Pearson eText to study how you like. NOTE: This ISBN is for the Pearson eText access card. Pearson eText is a fully digital delivery of Pearson content. Before purchasing, check that you have the correct ISBN. To register for and use Pearson eText, you may also need a course invite link, which your instructor will provide. Follow the instructions provided on the access card to learn more.
Teaching Science Through Inquiry-Based Instruction, with Enhanced Pearson eText -- Access Card Package
NOTE: Used books, rentals, and purchases made outside of Pearson If purchasing or renting from companies other than Pearson, the access codes for the Enhanced Pearson eText may not be included, may be incorrect, or may be previously redeemed. Check with the seller before completing your purchase. This package includes the Enhanced Pearson eText and bound print book. For an undergraduate level course in science education Teaching Science Through Inquiry-Based Instruction provides theory and practical advice for elementary and middle school teachers to help their students learn science. Written at a time of substantive change in science education, this book deals both with what’s currently happening and what’s expected in science classes in elementary and middle schools. Readers explore the nature of science, its importance in today’s world, trends in science education, and national science standards. The Thirteenth Edition is expanded to include information about the Next Generation Science Standards (NGSS) Performance Expectations for all elementary grade-level activities as well as the National Science Education Standards (NSES). Additionally, the book strives to present manageable ways to successfully bring inquiry into the science classroom by relating A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas and the 5E Instructional Model. Each chapter ends with suggested discussion questions and professional practice activities to encourage reflection and extend learning. New NGSS-aligned classroom activities provide examples of instruction that interweave the three dimensions of science. The Enhanced Pearson eText provides a rich, interactive learning environment designed to improve student mastery of content with embedded videos, assessment quizzes, and an activity library. The Enhanced Pearson eText* is: Engaging. The new interactive, multimedia learning features were developed by the authors and other subject-matter experts to deepen and enrich the learning experience.Convenient. Enjoy instant online access from your computer or download the Pearson eText App to read on or offline on your iPad® and Android® tablet.**Affordable. Experience the advantages of the Enhanced Pearson eText along with all the benefits of print for 40% to 50% less than a print bound book. *The Enhanced eText features are only available in the Pearson eText format. They are not available in third-party eTexts or downloads. **The Pearson eText App is available on Google Play and in the App Store. It requires Android OS 3.1-4, a 7” or 10” tablet, or iPad iOS 5.0 or later. 0134515471 / 9780134515472 Teaching Science Through Inquiry-Based Instruction, with Enhanced Pearson eText -- Access Card Package consists of: 0134516680 / 9780134516684 Teaching Science Through Inquiry-Based Instruction, Enhanced Pearson eText -- Access Card 0134516796 / 9780134516790 Teaching Science Through Inquiry-Based Instruction
Teaching Science Through Inquiry-Based Instruction -- Enhanced Pearson eText

Teaching Science Through Inquiry-Based Instruction -- Enhanced Pearson eText

Terry Contant; Joel Bass; Anne Tweed; Arthur Carin

Pearson
2017
lisenssiavain
For undergraduate level courses in elementary science methods. Teaching Science Through Inquiry-Based Instruction provides theory and practical advice for elementary and middle school teachers to help their students learn science. Written at a time of substantive change in science education, this book deals both with what's currently happening and what's expected in science classes in elementary and middle schools. Readers explore the nature of science, its importance in today's world, trends in science education, and national science standards. The 13th Edition is expanded to include information about the Next Generation Science Standards (NGSS) Performance Expectations for all elementary grade-level activities as well as the National Science Education Standards (NSES). Additionally, the book strives to present manageable ways to successfully bring inquiry into the science classroom by relating A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas and the 5E Instructional Model. Each chapter ends with suggested discussion questions and professional practice activities to encourage reflection and extend learning. New NGSS-aligned classroom activities provide examples of instruction that interweave the three dimensions of science. Pearson eText is an easy-to-use digital textbook that you can purchase on your own or instructors can assign for their course. The mobile app lets you keep on learning, no matter where your day takes you, even offline. You can also add highlights, bookmarks, and notes in your Pearson eText to study how you like. NOTE: This ISBN is for the Pearson eText access card. Pearson eText is a fully digital delivery of Pearson content. Before purchasing, check that you have the correct ISBN. To register for and use Pearson eText, you may also need a course invite link, which your instructor will provide. Follow the instructions provided on the access card to learn more.
Teaching Science Through Inquiry-Based Instruction

Teaching Science Through Inquiry-Based Instruction

Terry Contant; Joel Bass; Anne Tweed; Arthur Carin

Pearson
2017
nidottu
Note: This is the bound book only and does not include access to the Enhanced Pearson eText. To order the Enhanced Pearson eText packaged with a bound book, use ISBN 0134515471. For an undergraduate level course in science education Teaching Science Through Inquiry-Based Instruction provides theory and practical advice for elementary and middle school teachers to help their students learn science. Written at a time of substantive change in science education, this book deals both with what’s currently happening and what’s expected in science classes in elementary and middle schools. Readers explore the nature of science, its importance in today’s world, trends in science education, and national science standards. The Thirteenth Edition is expanded to include information about the Next Generation Science Standards (NGSS) Performance Expectations for all elementary grade-level activities as well as the National Science Education Standards (NSES). Additionally, the book strives to present manageable ways to successfully bring inquiry into the science classroom by relating A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas and the 5E Instructional Model. Each chapter ends with suggested discussion questions and professional practice activities to encourage reflection and extend learning. New NGSS-aligned classroom activities provide examples of instruction that interweave the three dimensions of science. The Enhanced Pearson eText provides a rich, interactive learning environment designed to improve student mastery of content with embedded videos, assessment quizzes, and an activity library. The Enhanced Pearson eText* is: Engaging. The new interactive, multimedia learning features were developed by the authors and other subject-matter experts to deepen and enrich the learning experience.Convenient. Enjoy instant online access from your computer or download the Pearson eText App to read on or offline on your iPad® and Android® tablet.**Affordable. Experience the advantages of the Enhanced Pearson eText along with all the benefits of print for 40% to 50% less than a print bound book. *The Enhanced eText features are only available in the Pearson eText format. They are not available in third-party eTexts or downloads. **The Pearson eText App is available on Google Play and in the App Store. It requires Android OS 3.1-4, a 7” or 10” tablet, or iPad iOS 5.0 or later.
The Saga of Erik the Viking
This is the tale of a Viking warrior by the name of Erik. But Erik is no ordinary Viking. With his trusty band of men he sets sail in search of the land where the sun goes at night – but he finds much more! The Sea Dragon, Dogfighters and giants combine to make his voyage a great saga of thrilling adventures.Written by Terry Jones, most famous for his membership of the Monty Python team, this is a wonderful tale, expertly spun, which won the Children’s Book Award.
Fairy Tales

Fairy Tales

Terry Jones

Puffin
1987
pokkari
Three raindrops have an argument on their way out of a cloud … A silly King goes for a walk with a dog tied to each leg … An enterprising herring, bored of the North Sea, decides to swim right round the world … Thirty short stories of magic and adventure penned by Monty Python team member, Terry Jones. Embracing the tradition of the fairy tale, but adding Jones’s inimitable comic imagination and originality, each story makes a perfect bedtime read for children – and grown ups!‘Could become a “modern classic” … the book is a joy’ Brian Patten, Spectator.
After Theory

After Theory

Terry Eagleton

Penguin Books Ltd
2004
pokkari
The golden age of cultural theory (the product of a decade and a half, from 1965 to 1980) is long past. We are living now in its aftermath, in an age which, having grown rich in the insights of thinkers like Althusser, Barthes and Derrida, has also moved beyond them. What kind of new, fresh thinking does this new era demand? Eagleton concludes that cultural theory must start thinking ambitiously again - not so that it can hand the West its legitimation, but so that it can seek to make sense of the grand narratives in which it is now embroiled.
Hell Riders

Hell Riders

Terry Brighton

Penguin Books Ltd
2005
pokkari
On 25 October 1854, during the Crimean War, the Light Brigade of the British Cavalry Division made the most magnificent and most brutal charge in military history. Almost 700 men armed with sabre and lance, charged straight at the muzzles of Russian cannons. This vivid and extraordinarily detailed account of the charge and the bloody mêlée that followed, by an author with unique access to regimental archives, is told largely in the words of the survivors themselves. Terry Brighton takes the reader closer than ever before to the experience of charging down the Valley of Death.
Masters of Battle

Masters of Battle

Terry Brighton

Penguin Books Ltd
2009
pokkari
'They should put Montgomery and Patton and Rommel in the same ring and take off the gloves and let 'em go at it' Bill Mauldin, American GIIn the Second World War, Great Britain, the United States and Germany each had one commander who stood out from the rest: Bernard Montgomery, George Patton and Erwin Rommel. In Masters of Battle, all three are 'put in the same ring' and allowed to 'go at it' against a backdrop of the great armoured battles of North Africa, the invasions of Sicily and Italy, the Normandy landings and the push through France and Belgium into Germany.Through the mutual respect of the arch-enemies Monty and Rommel, and the mutual animosity of the allies Monty and Patton, Masters of Battle presents the Second World War as it was experienced by its three most flamboyant, controversial and influential commanders.
John Birch

John Birch

Terry Lautz

Oxford University Press Inc
2016
sidottu
John Birch is a totemic figure in American life. The society named after him is one of the famous far-right organizations in American history. It was also a paradigmatic example of anti-communist hysteria during the Cold War, and its influence on the American far right to this day remains significant. Yet despite his posthumous fame, Birch himself remains an obscure figure. Terry Lautz, a longtime scholar of US-China relations, has spoken with all of Birch's remaining relatives, found shoeboxes filled with letters from one of his former lovers, and visited the various sites in China where he worked. The result is the first authoritative biography of this fascinating figure, who continues to haunt the political fringes of American life. Birch grew up in the rapidly growing Bible culture of the post-World War I period, and then became a missionary in China in the tumultuous period of its war against the Japanese and the escalating conflict between nationalists and communists. He fought with Claire Chennault's famed Flying Tigers and had a number of romantic relationships with women along the way. After the war ended, he committed himself to resuming his missionary activities in China, but was killed by communist guerrillas in an altercation a couple of weeks after the war ended in September 1945. A few years after his death, when China fell to the communists, anti-communists in Congress latched onto his life and promoted him as a martyr. Within a few years, Robert Welch, a candy manufacturer in New England, formed the John Birch Society, an extreme right-wing organization whose influence is still visible in the Tea Party movement. Lautz covers Birch's life and his afterlife, and also places him not merely in the context of the American far right, but in the revolutionary war that consumed China in the 1930s and 1940s. In this critical study of a figure who has reached near-legendary status, Lautz cuts through the mythology to expose John Birch-both the man and the political phenomenon.
Why Is That Art?: Aesthetics and Criticism of Contemporary Art
Why is that art? Why is it in an art museum? Who says it's art? Why is it good? Why Is That Art?, Third Edition, introduces students to theories of art through the presentation of contemporary works that include abstract and representational painting, animated film, monumental sculpture, performance art, photographs, relational art, and video installations. Ideal for courses in aesthetics, art theory, art criticism, and the philosophy of art, this unique book provides students with a newfound appreciation for contemporary art, scholarship, and reasoned argumentation.
The Priest and the Prophetess

The Priest and the Prophetess

Terry Rey

Oxford University Press Inc
2017
sidottu
By 1791, the French Revolution had spread to Haïti, where slaves and free blacks alike had begun demanding civil rights guaranteed in the 1789 Declaration of the Rights of Man. Enter Romaine-la-Prophétesse, a free black Dominican coffee farmer who dressed in women's clothes and claimed that the Virgin Mary was his godmother. Inspired by mystical revelations from the Holy Mother, he amassed a large and volatile following of insurgents who would go on to sack countless plantations and conquer the coastal cities of Jacmel and Léogâne. For this brief period, Romaine counted as his political adviser the white French Catholic priest and physician Abbé Ouvière, a renaissance man of cunning politics who would go on to become a pioneering figure in early American science and medicine. Brought together by Catholicism and the turmoil of the revolutionary Atlantic, the priest and the prophetess would come to symbolize the enlightenment ideals of freedom and a more just social order in the eighteenth-century Caribbean. Drawing on extensive archival research, Terry Rey offers a major contribution to our understanding of Catholic mysticism and traditional African religious practices at the time of the Haitian Revolution and reveals the significant ways in which religion and race intersected in the turbulence and triumphs of revolutionary France, Haïti, and early republican America.
Fortune's Fool

Fortune's Fool

Terry Alford

Oxford University Press Inc
2018
nidottu
With a single shot from a pistol small enough to conceal in his hand, John Wilkes Booth catapulted into history on the night of April 14, 1865. The assassination of President Abraham Lincoln stunned a nation that was just emerging from the chaos and calamity of the Civil War, and the president's untimely death altered the trajectory of postwar history. But to those who knew Booth, the event was even more shocking-for no one could have imagined that this fantastically gifted actor and well-liked man could commit such an atrocity. In Fortune's Fool, Terry Alford provides the first comprehensive look at the life of an enigmatic figure whose life has been overshadowed by his final, infamous act. Tracing Booth's story from his uncertain childhood in Maryland, characterized by a difficult relationship with his famous actor father, to his successful acting career on stages across the country, Alford offers a nuanced picture of Booth as a public figure, performer, and deeply troubled man. Despite the fame and success that attended Booth's career--he was billed at one point as "the youngest star in the world"--he found himself consumed by the Confederate cause and the desire to help the South win its independence. Alford reveals the tormented path that led Booth to conclude, as the Confederacy collapsed in April 1865, that the only way to revive the South and punish the North for the war would be to murder Lincoln--whatever the cost to himself or others. The textured and compelling narrative gives new depth to the familiar events at Ford's Theatre and the aftermath that followed, culminating in Booth's capture and death at the hands of Union soldiers 150 years ago. Based on original research into government archives, historical libraries, and family records, Fortune's Fool offers the definitive portrait of John Wilkes Booth.
Physician Communication

Physician Communication

Terry L. Schraeder

Oxford University Press Inc
2019
nidottu
Communication skills determine how the world perceives us - and how we perceive the world. Communication is at the heart of who we are and all that we do. As a clinician, your communication impacts how you take care of patients, work with colleagues, teach trainees, and engage audiences and the public. Communication encompasses all aspects of human skills, from listening and clearly articulating thoughts to an awareness of physical gestures, specific word choice, tone, and volume. Whether engaging with patients, peers, care teams, family members, residents, researchers, insurance agencies, management, or journalists, successful communication requires focusing on the importance of the relationship and the mission of each interaction. Today, due to the rise of digital technologies including electronic medical records, online forums, and video conferences, the content of information, the platform, and the audience are continuously changing and expanding for physicians. There is a great need in the physician community to learn how to facilitate the exchange of information, provide psychosocial support, partake in shared-decision making, translate complex information, and resolve controversies with sound science in a variety of settings. Addressing physicians at every level of training and practice, Physician Communication: Connecting with Patients, Peers, and the Public will enable providers to examine, analyse, and improve their skills in the art and science of communication. Divided into four sections: Face-to-face Communications; Digital Communications;Public Speaking; and Traditional Media, this book will help physicians navigate various situations using different methods and modes of communication.