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Imunoterapia com IgY aviária em ratos experimentalmente infectados

Imunoterapia com IgY aviária em ratos experimentalmente infectados

Luzia Cristina Lencioni Sampaio; Charles F Martins; Fernanda A Franco

Novas Edicoes Academicas
2018
pokkari
Trypanosoma evansi um protozo rio flagelado que acomete bovinos, ovinos, caprinos, asininos, felinos e su nos. A enfermidade tem especial import ncia em equinos, sendo conhecida como "mal das cadeiras", devido aos d ficits de locomo o caracter sticos em animais infectados. V rias drogas terap uticas t m sido recomendadas para a profilaxia e controle do protozo rio, por m ao longo dos anos estes medicamentos t m perdido a efic cia e o protozo rio parece desenvolver resist ncia. A produ o e uso de anticorpos avi rios tem despertado grande interesse na comunidade cient fica devido diversidade de aplica es diagn sticas e terap uticas. Devido dist ncia filogen tica, mecanismos de diversifica o imune e capacidade de transfer ncia das imunoglobulinas s ricas para a gema do ovo, atualmente reconhece-se uma s rie de vantagens ao utilizar anticorpos avi rios ao inv s de anticorpos de mam feros. Neste estudo foi produzido uma imunoglobulina espec fica contra o T. evansi a partir de imuniza o de galinhas usando um isolado do protozo rio. A efic cia terap utica foi testada em Rattus norvegicus.
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Stratégies organisationnelles

Stratégies organisationnelles

Skarlaty Ohara de Jesus; Graziela Luiz F Martinez

Editions Notre Savoir
2024
pokkari
La recherche vise expliquer les strat gies organisationnelles adopt es par une entreprise de loisirs et de tourisme, depuis sa cr ation jusqu' aujourd'hui. Pour ce faire, il a t n cessaire d'identifier historiquement les actions strat giques, de les classer selon les strat gies organisationnelles et enfin de les analyser. L' tude est descriptive et l'approche est qualitative-quantitative. Pour collecter les donn es, des entretiens ont t r alis s et des questionnaires semi-structur s avec des questions ouvertes et ferm es ont t appliqu s. Apr s avoir identifi historiquement les actions strat giques de l'entreprise, on s'est rendu compte qu'elle avait des actions caract ristiques des strat gies de survie, de maintien, de d veloppement et de croissance. Avec la moyenne arithm tique de chaque strat gie organisationnelle, on peut consid rer que l'entreprise adopte fr quemment la strat gie de croissance avec un niveau de 2,7, mod r ment la strat gie de d veloppement avec un niveau de 2,4, rarement la strat gie de survie en p riode de basse saison avec un niveau de 1,6 et rarement la strat gie de maintien avec un niveau de 1,3.
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Organisatorische Strategien

Organisatorische Strategien

Skarlaty Ohara de Jesus; Graziela Luiz F Martinez

Verlag Unser Wissen
2024
pokkari
Die Untersuchung zielt darauf ab, die von einem Freizeit- und Tourismusunternehmen angewandten organisatorischen Strategien von der Gr ndung bis zur Gegenwart zu erkl ren. Dazu war es notwendig, die strategischen Aktionen historisch zu identifizieren, sie nach organisatorischen Strategien zu klassifizieren und schlie lich zu analysieren. Es handelt sich um eine deskriptive Studie mit einem qualitativ-quantitativen Ansatz. Zur Datenerhebung wurden Interviews durchgef hrt und halbstrukturierte Frageb gen mit offenen und geschlossenen Fragen verwendet. Nach der historischen Identifizierung der strategischen Ma nahmen des Unternehmens wurde festgestellt, dass es Ma nahmen gibt, die f r berlebens-, Erhaltungs-, Entwicklungs- und Wachstumsstrategien charakteristisch sind. Aus dem arithmetischen Mittelwert der einzelnen Organisationsstrategien l sst sich ableiten, dass das Unternehmen h ufig die Wachstumsstrategie mit einem Wert von 2,7, m ig die Entwicklungsstrategie mit einem Wert von 2,4, selten die berlebensstrategie in der Nebensaison mit einem Wert von 1,6 und selten die Instandhaltungsstrategie mit einem Wert von 1,3 anwendet.
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Strategie organizzative

Strategie organizzative

Skarlaty Ohara de Jesus; Graziela Luiz F Martinez

Edizioni Sapienza
2024
pokkari
La ricerca si propone di spiegare le strategie organizzative adottate da un'azienda turistica e del tempo libero, dalla sua creazione a oggi. Per farlo, stato necessario identificare storicamente le azioni strategiche, classificarle in base alle strategie organizzative e infine analizzarle. Lo studio di tipo descrittivo e l'approccio di tipo quali-quantitativo. Per la raccolta dei dati sono state realizzate interviste e sono stati applicati questionari semi-strutturati con domande aperte e chiuse. Dopo aver identificato storicamente le azioni strategiche dell'azienda, ci si resi conto che essa aveva azioni caratteristiche delle strategie di sopravvivenza, mantenimento, sviluppo e crescita. Con la media aritmetica di ogni strategia organizzativa, si pu ritenere che l'azienda adotti frequentemente la strategia di crescita con un livello di 2,7, moderatamente la strategia di sviluppo con un livello di 2,4, raramente la strategia di sopravvivenza nei periodi di bassa stagione con un livello di 1,6 e raramente la strategia di mantenimento con un livello di 1,3.
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Organizational strategies

Organizational strategies

Skarlaty Ohara de Jesus; Graziela Luiz F Martinez

Our Knowledge Publishing
2024
pokkari
The research aims to explain the organizational strategies adopted by a leisure and tourism company, from its inception to the present day. To this end, it was necessary to historically identify strategic actions, classify them according to organizational strategies and finally analyze them. The study is descriptive, and the approach is qualitative-quantitative. To collect data, interviews were carried out and semi-structured questionnaires with open and closed questions were applied. After historically identifying the company's strategic actions, it was realized that it had actions characteristic of survival, maintenance, development and growth strategies. With the arithmetic mean of each organizational strategy, it can be considered that the company frequently adopts the growth strategy with a level of 2.7, moderately the development strategy with a level of 2.4, rarely the survival strategy in low season periods with a level of 1.6 and rarely the maintenance strategy with a level of 1.3.
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Lockheed-Martin F-22 Raptor

Lockheed-Martin F-22 Raptor

Mike Wallace

Schiffer Publishing Ltd
1998
nidottu
It’s called the Raptor. The F-22 will be the U.S. Air Force’s premier fighter for the first decades of the 21st century. Like other expensive military programs, the F-22 endured continuous scrutiny throughout its development – the aircraft that evolved was worth the wait. The F-22 is definitely “top gun” – it is more agile than current U.S. aircraft, has stealth capability, and is flexible in both air-to-air and air-to-ground attack missions. The Raptor is planned to start operational service with the U.S. Air Force in the year 2004, and when on-line, will provide a capability far beyond that of any other fighter aircraft.
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Flight Craft 33: Lockheed Martin F-35 Lightning II

Flight Craft 33: Lockheed Martin F-35 Lightning II

Ben Skipper

PEN SWORD BOOKS LTD
2025
nidottu
The Lockheed Martin F-35 Lightning II is heralded as the ultimate fifth-generation fighter, merging advanced engineering with multinational collaboration. Developed during a time of military reorganization and technological mergers, it integrates the best features of previous generations into a versatile platform for varied operational roles across military branches. The F-35 is the first fifth-generation multi-service aircraft designed for continuous technological evolution. Despite funding delays and complexities, it remains the largest defense contract in history. Its three variants serve diverse roles: the F-35A for conventional take-off and landing (CTOL), the F-35B for short take-off and vertical landing (STOVL), and the F-35C for carrier operations with Catapult-Assisted Take-Off But Arrested Recovery (CATOBAR). Since its inaugural flight on December 15, 2006, the F-35 has demonstrated exceptional capabilities, becoming a cornerstone of air forces worldwide. Designed to maintain air superiority into the 2070s, it represents the pinnacle of stealth and multi-role combat.
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