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Corporate DNA

Corporate DNA

Ken Baskin

Butterworth-Heinemann Ltd
1998
nidottu
Corporate DNA explores what happens when managers think about and run their companies as if they were living things. An organic model is at the heart of the transformation of companies like AT&T and EDS, working to redesign the bureaucracies that they were built upon. This book addresses the frustrations felt among corporations by focusing on the role of the organizational models in the transformation process. The book's key perception is that the choice of a mechanical or organic model results in an organizations developing either mechanical or organic structures. Those structures, in turn, lead to certain types of behavior. Corporate DNA provides tools with which managers can replace their old mechanical models with organic ones. Readers will discover how living things use information to create work; how they learn, develop, and govern themselves; and how prototype organic corporations such as 3M and Federal Express apply organic models to their operations. Ken Baskin, Ph.D., is a consultant on communicating quality and culture change. In addition to his own public relations business, he has worked for the US Department of Energy, the New Jersey Department of Education, and Bell Atlantic, including speech writing for CEO Ray Smith. Ken leads workshops on ¦Creating Competitive Advantage in a Market Ecology¦ and ¦Using the Principles of DNA for Problem Solving,¦ among others.
Nonhuman DNA Typing

Nonhuman DNA Typing

CRC Press Inc
2007
sidottu
The association of a suspect with the victim or crime scene through DNA evidence is one of the most powerful statements of complicity in a crime imaginable. No category of evidence has ever had the complete capacity to convict or exonerate an accused so absolutely in the eyes of the public. With the discriminatory powers of DNA and the variety of DNA markers now in regular use, the one thing keeping a third of all cases unsolved is the lack of human DNA evidence. However, the identification of polymorphic genetic loci in cats, dogs, plants, insects, bacteria, and viruses can provide the critical link between suspect and scene in the absence of human DNA. Non-Human DNA Typing: Theory and Casework Applications provides an introduction to the basic science underlying the emerging field of non-human DNA typing. It examines the use of non-human DNA evidence not just in homicide cases, but also in drug trafficking, poaching of endangered species, livestock fraud, and missing persons, as well as the identification of primary and secondary crime scenes. The book demonstrates the recognition, collection, and preservation of biological evidence at a crime scene, techniques of DNA fingerprinting, and DNA profiling. Using a wide variety of examples, applications, and case studies, the author describes the STR analysis of canine and feline samples, insects, and fungi, and their role as evidence in forensic science. Chapters consider the development of testing methods for animal evidence, soil DNA typing, and the use of DNA typing in wildlife investigations. A useful appendix includes an overview of the history of forensic serology and DNA. Combining science, case examples, legal decisions, and references, Non-Human DNA Typing: Theory and Casework Applications presents the forensic and legal applications of non-human DNA evidence for scientists, law enforcement, and attorneys.
Recombinant DNA Principles and Methodologies
This comprehensive yet balanced work emphasizes the principles and rationale underlying recombinant DNA methodology while furnishing a general understanding of the experimental protocols-suggesting flexible approaches to resolving particular molecular necessities that are easily adaptable to readers' specific applications. Features summary tables presenting at-a-glance information on practices of recombinant DNA methodologies!Recombinant DNA Principles and Methodologies discusses basic and advanced topics requisite to the employment of recombinant DNA technology, such asplasmid biology nucleic acid biochemistry restriction enzymes cloning strategies gel electrophoresis southern and northern blotting preparation of probes phage lambda biology cosmids and genome analysis cloned gene expression polymerase chain reaction conventional and automated DNA sequencing site-directed mutagenesis and more! Elucidating the material with over 2250 edifying references, equations, drawings, and photographs, this state-of-the-art resource is a valuable hands-on guide for molecular and cell biologists, biochemists, bioprocess technologists, applied and industrial microbiologists, virologists, geneticists, chemical engineers, and upper-level undergraduate and graduate students in these disciplines.
Artificial DNA

Artificial DNA

CRC Press Inc
2002
sidottu
Combining elements of biochemistry, molecular biology, and immunology, artificial DNA can be employed in a number of scientific disciplines. Some of the varied applications include site-specific mutagenesis, hybridization, amplification, protein engineering, anti-sense technology, DNA vaccines, protein vaccines, recombinant antibodies, screening for genetic and pathogenic diseases, development of materials with new biochemical and structural properties, and many more. Artificial DNA: Methods and Applications introduces the concept of artificial DNA that has been rationally designed and explains how it may be exploited in order to develop products that will achieve your intended purpose. The first part of the book covers methods of oligonucleotide synthesis and direct applications of synthetic DNA. The second part describes methods of gene assembly from synthetic oligonucleotides and applications of synthetic genes. The authors also discuss the different trends and future developments within each application area . With state-of-the art research, the contributing authors describe how to engineer proteins using rational and semi-rational design to exhibit the desired traits and detail the various amplification reactions and hybridization techniques for modeling evolution and for use in basic research. The only text devoted to this subject, Artificial DNA offers a comprehensive review that allows you to understand the strategy, design, and applications of synthetic oligonucleotides.
From DNA Photolesions to Mutations, Skin Cancer and Cell Death
As modern day society takes an increasing interest in outdoor activities, its exposure to sunlight has never been greater. As a consequence, countries throughout the world are experiencing a dramatic increase in the incidences of skin carcinomas and melanomas. From DNA photolesions to mutations, skin cancer and cell death provides an authoritative source of information for photobiologists interested in the series of genetic events that occur in the skin, and eventually lead to cancer. With contributions from eminent scientists in the field, this book includes the latest information on DNA photolesions and repair, as well as the key mechanisms of solar UV in skin cancer initiation and development. Significant information relating to UV-induced photolesions and mechanisms of skin tumour occurrence is also included. By providing the basic phenomena underlying the science and an overview of the biological events that take place when cells are exposed to solar UV radiation, From DNA photolesions to mutations, skin cancer and cell death is suitable to all researchers interested in the process of photocarcinogenesis.
The DNA of D6: Building Blocks of Generational Discipleship
This book will help the reader understand a timeless philosophy leading to a better plan of implementing a strategy for generational discipleship. Ron Hunter provides any church an opportunity to plan, strategize, evaluate, and refine their family ministry. Programs do not provide cultural changes, principles do. This book will walk the reader through important principles that will lead to implementation. The author shares from a wealth of experience and wants all ministry leaders to have a solid plan for generational discipleship. Chapters include: The Unseen Staff Member, 1/168 A Flawed Fraction or Ministry Multiplier, and The One-Eared Mickey Mouse.
Forensic DNA Profiling Protocols
It is now more than ten years since Dr. Alec Jeffreys (now Professor Sir Alec Jeffreys, FRS) reported in Nature that the investigation of certain minisatellite regions in the human genome could produce what he termed DNA fingerprints and provide useful information in the fields of paternity testing and forensic analysis. Since that time we have witnessed a revolution in the field of forensic identification. A total change of technology, from serological or electrophoretic analysis of protein polymorphisms to direct investigation of the underlying DNA polymorphisms has occurred in a short space of time. In addition, the evolution and development of the DNA systems themselves has been rapid and spectacular. In the last decade we have progressed from the multilocus DNA fing- prints, through single locus systems based on the same Southern blot RFLP technology, to a host of systems based on the PCR technique. These include Allele Specific Oligonucleotide (ASO)-primed systems detected by dot blots, the “binary” genotypes produced by mapping variations within VNTR repeats demonstrated by minisatellite variant repeat (MVR) analysis, and yet other fragment-length polymorphisms in the form of Short Tandem Repeat (STR) loci. Hand in hand with the increasing range of systems available has been the development of new instrumentation to facilitate their analysis and allow us to explore the possibilities of high volume testing in the form of mass scre- ing and offender databases.
Recombinant DNA Research and Viruses

Recombinant DNA Research and Viruses

Kluwer Academic Publishers
1984
sidottu
The development of recombinant DNA technology has made a marked impact on molecular virology. The cleavage of viral DNA genomes with restriction enzymes and the cloning of such DNA fragments in bacterial p1asmids has led to the amplification of selected viral DNA fragments for sequencing and gene expression. RNA virus genomes which can be transcribed to their cDNA form were also cloned in bacterial p1asmids, facilitating the study of RNA virus genes. With the elucidation in recent years of the promoter sequence of various viral genes and the expression of these genes in bacteria or yeast, the understanding of many viral gene functions has made great progress. Cloning and expression of viral genes in mammalian cells was made possible by the construction of shuttle plasmid vectors which carry the origins of DNA replication from bacteria and/or mammalian viruses. The expression of viral genes in bacteria, yeast and eukaryotic cells gives reason to hope that it will be possible to produce viral antigens in large quantities for use as human or animal vaccines. The present volume attempts to capture for the reader some of the high­ lights of recombinant DNA research in the field of animal and plant viruses.
Adenovirus DNA

Adenovirus DNA

Kluwer Academic Publishers
1985
sidottu
Although adenoviruses have been established for quite some time as one of the most pliable tools to study the molecular biology of mammalian cells, rapid progress continues to be made with this virus system. The adenoviral genome introduced into the nucleus of cells as a Trojan Horse, as it were, is now facili- tating investigators to uncover details of cellular mechanisms. In this volume twelve chapters have been collected that summarize important current research on different mechanisms in adenovirus- infected and -transformed cells. It has become increasingly apparent that some of these mechanisms do not only pertain to highly specialized strategies of the viral genome and its expres- sion or replication, but may simultaneously shed light on events indigenous to the cell. "Adenovirus DNA: The Viral Genome and its Expression" high- lights the first publication of the entire annotated sequence of 35. 937 nucleotide pairs of adenovirus type 2 DNA by the Cold Spring Harbor and Uppsala groups (chapter 1). Goran Akusjarvi, Ulf Pettersson (Uppsala University) and Rich Roberts (Cold Spring Harbor) present a survey on the structure and function of the adenovirus-2 genome (chapter 2). A considerable amount of in- formation has been collected on the biochemical mechanisms in- vol ved in adenov irus DNA repl ication in human cells. Al though highly specialized in the way of initiating DNA replication, adenov irus DNA repl ication represents probably one of the best studied systems in work on eukaryotic DNA replication.
The DNA of Democracy: Volume 1

The DNA of Democracy: Volume 1

Richard C. Lyons

Lylea Creative Resources, LLC
2019
nidottu
An American poet writes a compilation of historical vignettes, discerning the future of our democracy by rediscovering the combative, instructive, fascinating past of tyranny and democracy. Just as DNA is interwoven in every aspect of the human body, tyranny and democracy have their historically distinctive DNA that have shaped our democracy today. From Israel's Ten Commandments, to the Athenian Constitution, to Rome's Twelve Tables, to the overthrow of kings in England and America, Lyons traces democracy from its historical roots to the modern day, constructing a blueprint of what defines tyranny or democratic government in The DNA of Democracy. In this definitive guide, Richard C. Lyons documents the struggle for power between tyrants and heroes across time and place. Chronicling the acts of tyrants which are expressive of tyranny's DNA, and the rebellions of heroes and the forms of law which are democracy's DNA--Lyons outlines the roots of democracies, by telling the tales of tyrants who ironically gave them birth-- births of rebellion This book serves as a how to contemporary guide on identifying the menace of a tyrant when you see one
Brand DNA

Brand DNA

Suzanne Tulien

Brand Ascension Publishing
2010
pokkari
If you are like most small businesses, getting customers in the door is a priority and sometimes an all consuming and expensive effort. What's truly missing in this business building effort is creating a compelling, differentiating and consistent brand experience from the inside out that keeps your employees on-brand and your customers coming back, (and telling their friends ) Brand DNA is the bridge to that missing piece; an internal strategic brand positioning program designed to clarify and leverage your organization's genetic code for competitive advantage in a step-by-step process. So, dare to dig deep to unearth and clearly articulate your value position and cultivate your organizational leadership, culture, and processes to walk your talk and deliver on your promise for unparalleled brand advantage long-term Leverage your Brand DNA attributes within your marketing efforts to create true distinction & a consistent narrative.Create 'on-brand' consistencies in your actions/behaviors and processes that build trust and advocacy.Build an engaging, 'on-brand' culture, while attracting and recruiting top talent.Discern differently, with confidence and brand clarity in how you continue to expand and grow..