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Insuficiência renal em adultos zambianos em tratamento com tenofovir

Insuficiência renal em adultos zambianos em tratamento com tenofovir

Freeman Chabala

Edicoes Nosso Conhecimento
2025
pokkari
A preval ncia de insufici ncia renal entre adultos com VIH/SIDA na Z mbia est estimada em 34,5% e a probabilidade de morte mais comum nestes doentes do que naqueles sem insufici ncia renal. O tenofovir tem estado na primeira linha do regime ARV na Z mbia desde 2007; substituindo a estavudina e a zidovudina. Isto foi recomendado e adotado apesar de muitos estudos em pa ses industrializados terem associado o tenofovir a tubulopatia renal e nefrotoxicidade. Um estudo transversal anal tico concebido para determinar a probabilidade de adultos com VIH/SIDA desenvolverem insufici ncia renal ap s um ano de tratamento com tenofovir no maior centro de TAR da Z mbia. A investiga o incluiu 549 adultos que estiveram em tratamento de 2007 a 2013; 274 em tenofovir e 275 em estavudina ou zidovudina. Os resultados revelaram que os pacientes que tomavam tenofovir tinham 8,77 vezes mais probabilidades de desenvolver insufici ncia renal do que os que tomavam estavudina ou zidovudina, depois de controlar a idade e o g nero.
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Insuffisance rénale chez les adultes zambiens traités au ténofovir

Insuffisance rénale chez les adultes zambiens traités au ténofovir

Freeman Chabala

Editions Notre Savoir
2025
pokkari
La pr valence de l'insuffisance r nale chez les adultes atteints du VIH/SIDA en Zambie est estim e 34,5 % et la probabilit de d c s est plus lev e chez ces patients que chez ceux qui ne souffrent pas d'insuffisance r nale. Le t nofovir fait partie du traitement ARV de premi re intention en Zambie depuis 2007, en remplacement de la stavudine et de la zidovudine. Ce traitement a t recommand et adopt bien que de nombreuses tudes men es dans les pays industrialis s aient associ le t nofovir la tubulopathie r nale et la n phrotoxicit . Une tude transversale analytique a t con ue pour d terminer la probabilit que des adultes atteints du VIH/SIDA d veloppent une insuffisance r nale apr s un an de traitement au t nofovir dans le plus grand centre de traitement antir troviral de Zambie. L' tude a port sur 549 adultes trait s entre 2007 et 2013, dont 274 sous t nofovir et 275 sous stavudine ou zidovudine. Les r sultats ont r v l que les patients sous t nofovir taient 8,77 fois plus susceptibles de d velopper une insuffisance r nale que ceux sous stavudine ou zidovudine, apr s prise en compte de l' ge et du sexe.
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London Murder Mysteries - Ultimate Collection

London Murder Mysteries - Ultimate Collection

Freeman Wills Crofts

e-artnow
2022
pokkari
CDATA The Cask - A suspicious cask arrives in London dock which when unloading slips and cracks open to reveal gold sovereigns. While the bystanders scramble to pick up the gold, the dock inspector finds a hand of a dead woman buried underneath. To his absolute bewilderment, the next day, the cask has disappeared Now it is up to Inspector Burnley of Scotland Yard to solve the mystery of the cask as well as the murder of the woman.The Ponson Case - When the dead body of Sir William Ponson is found in a nearby river, he is presumed to have died due to drowning. But then the clues start pointing towards a gruesome murder. Now it is up to Inspector Tanner to find the owner of the mysterious footprints and prevent the estate from falling into the hands of Sir William's murderers.The Pit-Prop Syndicate - Seymour Merriman would not have even imagined that a little bit of help from strangers would catapult him into the world of crime syndicate, spanning two continents. He had only followed Lorry Number 3 in the hopes of getting some petrol for his bike. But that ended up with him noticing that the number plates had been changed Why were the number plates changed? Who were these people whom Seymour had inadvertently met?]]
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The Cask: A Murder Mystery

The Cask: A Murder Mystery

Freeman Wills Crofts

e-artnow
2022
nidottu
In "The Cask," Freeman Wills Crofts crafts a masterful detective narrative that intricately weaves elements of suspense and intricate plotting. Set against the backdrop of early 20th-century Britain, the novel introduces readers to a compelling mystery centered around the disappearance of a man and a cask of wine that conceals more than it seems. Crofts' precision in detailing, coupled with his methodical narrative style, reflects the golden age of detective fiction, echoing the works of contemporaries such as Agatha Christie and Arthur Conan Doyle yet uniquely showcasing his trademark focus on the procedural aspects of criminal investigation. Freeman Wills Crofts, a civil engineer by profession, brought a meticulous attention to detail to his writing that is evident throughout the novel. His background played a significant role in shaping his realistic depictions of crimes and the methods of detection used to solve them. Crofts, who became one of the leading figures in the detective genre, often drew from his experiences in engineering and travel, lending a authenticity to the settings and situations that defined his work. Readers seeking a tightly woven mystery enriched with intellectual challenge will find "The Cask" both engaging and thought-provoking. Crofts not only entertains but invites readers to engage in logical deduction alongside his protagonists. This novel stands as a testament to the craftsmanship of Crofts, making it a valuable addition to the library of any enthusiast of classic detective fiction.
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The Ponson Case: A Murder Mystery

The Ponson Case: A Murder Mystery

Freeman Wills Crofts

e-artnow
2022
nidottu
In "The Ponson Case," Freeman Wills Crofts crafts a gripping detective narrative steeped in the conventions of the Golden Age of Crime Fiction. The novel intricately weaves a tale of mystery surrounding the disappearance of the wealthy businessman Hubert Ponson, skillfully employing Crofts' hallmark precision in plotting and his keen understanding of human psychology. The storytelling is characterized by a methodical unfolding of clues, drawing readers into a labyrinth of deception, while also reflecting the societal norms and class dynamics of the early 20th century British milieu. Crofts' adept use of the deductive reasoning prevalent in contemporary detective fiction accentuates the narrative's cerebral engagement and innovative structure, marking it as a notable example of its genre. Freeman Wills Crofts, a prominent figure in British detective literature, was deeply influenced by his background in engineering, which honed his logical reasoning and systematic thinking--qualities that permeate his writing. Born in 1879, Crofts served as an inspector of railways, experiences that would later inform the meticulous details and procedural aspects of his plots. His understanding of the intricacies of various professions and environments led him to create realistic scenarios, making "The Ponson Case" a reflection of his expertise and a compelling expression of his literary identity. Recommended for aficionados of classic detective fiction, "The Ponson Case" invites readers to engage with its pithy narrative and intricately designed puzzle. Its adept blend of suspense and intellect not only entertains but also provokes thought on the moral dilemmas faced by its characters. Crofts' nuanced approach to crime and justice provides a stimulating reading experience, ensuring that this novel remains an enduring piece in the canon of mystery literature.
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The Pit-Prop Syndicate: A Thrilling Crime Syndicate Saga

The Pit-Prop Syndicate: A Thrilling Crime Syndicate Saga

Freeman Wills Crofts

e-artnow
2022
nidottu
In "The Pit-Prop Syndicate," Freeman Wills Crofts delivers a gripping tale of intrigue set against the backdrop of the burgeoning post-World War I industrial landscape. The novel unfolds through meticulous plotting and Crofts' hallmark attention to detail, characteristic of the Golden Age of Detective Fiction. It tells the story of a mysterious syndicate involved in a nefarious scheme surrounding the coal industry, intertwining themes of morality, corruption, and the clash between progress and tradition. The narrative is rich with authentic period elements, engaging readers with its intricate puzzles and compelling characterization, ultimately leading to a gripping denouement. Freeman Wills Crofts, a prominent figure in the detective fiction genre, was trained as a civil engineer, which influenced his penchant for meticulous plotting and technical precision in his narratives. His rich understanding of industrial processes--including those related to mining and construction--imbues "The Pit-Prop Syndicate" with both authenticity and depth. Crofts' own experiences during the transformative years following World War I also inform the socio-economic themes that resonate throughout the novel, reflecting the complexities of a society in transition. This novel is highly recommended for anyone interested in classic detective stories, industrial intrigue, or the socio-economic narratives of early 20th-century Britain. Crofts' adept storytelling and intelligent plot construction will captivate seasoned readers and newcomers alike, making it an essential addition to any literary collection.
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The Cask

The Cask

Freeman Wills Crofts

True Sign Publishing House
2023
nidottu
"The Cask" is a detective novel by Freeman Wills Crofts, published in 1920. The story centers around a murder mystery involving a wine cask. A valuable cask of wine is delivered to a London wine merchant, but when opened, it contains the body of a murdered man. Inspector French, a recurring character in Crofts' detective stories, leads the investigation. With meticulous attention to detail and a logical, methodical approach, Inspector French works to unravel the complex web of clues, suspects, and motives surrounding the murder. "The Cask" is a classic example of puzzle-style detective fiction from the Golden Age of Detective Fiction, focusing on intricate plotting and the process of solving the mystery.
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History of the Borton and Mason families in Europe and America

History of the Borton and Mason families in Europe and America

Freeman C Mason

Alpha Edition
2020
pokkari
This book has been considered by academicians and scholars of great significance and value to literature. This forms a part of the knowledge base for future generations. So that the book is never forgotten we have represented this book in a print format as the same form as it was originally first published. Hence any marks or annotations seen are left intentionally to preserve its true nature.
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The Cask

The Cask

Freeman Wills Crofts

ALPHA EDITION
2021
pokkari
This book has been considered important throughout the human history, and so that this work is never forgotten we have made efforts in its preservation by republishing this book in a modern format for present and future generations. This whole book has been reformatted, retyped and designed. These books are not made of scanned copies of their original work and hence the text is clear and readable.
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The Cheyne Mystery

The Cheyne Mystery

Freeman Wills Crofts

Classy Publishing
2022
nidottu
From the Collins Crime Club archive, the second Inspector French novel by Freeman Wills Crofts, once dubbed 'The King of Detective Story Writers'. THE RETURN OF INSPECTOR FRENCH When young Maxwell Cheyne discovers that a series of mishaps are the result of unwelcome attention from a dangerous gang of criminals, he teams up with a young woman who is determined to help him outwit them. But when she disappears, he finally decides to go to Scotland Yard for help. Concerned by the developing situation, Inspector Joseph French takes charge of the investigation and applies his trademark methods to track down the kidnappers and thwart their intentions . . .
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The Pit-Prop Syndicate

The Pit-Prop Syndicate

Freeman Wills Crofts

True Sign Publishing House
2023
nidottu
""The Pit-Prop Syndicate"" is an intriguing detective novel by Freeman Wills Crofts, known for its intricate plot and meticulous attention to detail. Set in the early 20th century, the story revolves around the meticulous investigation led by Detective Inspector French, as he unravels the complexities surrounding a baffling crime within the coal industry. Amidst the backdrop of industrial England, Crofts weaves a tale of corporate sabotage, intricate alibis, and hidden motives, leading the reader through a labyrinth of clues and red herrings. With an emphasis on forensic detail and logical deduction, the novel showcases Crofts' mastery in crafting a tightly woven mystery, where every clue and revelation serves to deepen the enigma. ""The Pit-Prop Syndicate"" stands as a testament to Crofts' contribution to the classic detective genre, offering readers an engaging and intellectually stimulating journey into the world of crime and investigation.
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Inspector French's Greatest Case

Inspector French's Greatest Case

Freeman Wills Crofts

Alpha Editions
2022
pokkari
This Book "Inspector French's Greatest Case" has been considered important throughout the human history, and so that this work is never forgotten we have made efforts in its preservation by republishing this book in a modern format for present and future generations. This whole book has been reformatted, retyped and designed. These books are not made of scanned copies of their original work and hence the text is clear and readable.
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Quisanté

Quisanté

Freeman Wills Crofts

Alpha Editions
2023
nidottu
The Pit-Prop Syndicate, a classical book, has been considered essential throughout the human history, and so that this work is never forgotten we at Alpha Editions have made efforts in its preservation by republishing this book in a modern format for present and future generations. This whole book has been reformatted, retyped and designed. These books are not made of scanned copies of their original work and hence the text is clear and readable.
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Tintoretto (Edition1)

Tintoretto (Edition1)

Freeman Wills Crofts

Alpha Editions
2024
nidottu
The Starvel Hollow tragedy: An Inspector French case, a classical book, has been considered important throughout the human history, and so that this work is never forgotten we at Alpha Editions have made efforts in its preservation by republishing this book in a modern format for present and future generations. This whole book has been reformatted, retyped and designed. These books are not made of scanned copies of their original work and hence the text is clear and readable.
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Advanced Quantum Mechanics

Advanced Quantum Mechanics

Freeman J Dyson

World Scientific Publishing Co Pte Ltd
2007
sidottu
Renowned physicist and mathematician Freeman Dyson is famous for his work in quantum mechanics, nuclear weapons policy and bold visions for the future of humanity. In the 1940s, he was responsible for demonstrating the equivalence of the two formulations of quantum electrodynamics — Richard Feynman's diagrammatic path integral formulation and the variational methods developed by Julian Schwinger and Sin-Itiro Tomonoga — showing the mathematical consistency of QED.This invaluable volume comprises the legendary, never-before-published, lectures on quantum electrodynamics first given by Dyson at Cornell University in 1951. The late theorist Edwin Thompson Jaynes once remarked “For a generation of physicists they were the happy medium: clearer and motivated than Feynman, and getting to the point faster than Schwinger”.Future generations of physicists are bound to read these lectures with pleasure, benefiting from the lucid style that is so characteristic of Dyson's exposition.
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Advanced Quantum Mechanics

Advanced Quantum Mechanics

Freeman J Dyson

World Scientific Publishing Co Pte Ltd
2007
nidottu
Renowned physicist and mathematician Freeman Dyson is famous for his work in quantum mechanics, nuclear weapons policy and bold visions for the future of humanity. In the 1940s, he was responsible for demonstrating the equivalence of the two formulations of quantum electrodynamics — Richard Feynman's diagrammatic path integral formulation and the variational methods developed by Julian Schwinger and Sin-Itiro Tomonoga — showing the mathematical consistency of QED.This invaluable volume comprises the legendary, never-before-published, lectures on quantum electrodynamics first given by Dyson at Cornell University in 1951. The late theorist Edwin Thompson Jaynes once remarked “For a generation of physicists they were the happy medium: clearer and motivated than Feynman, and getting to the point faster than Schwinger”.Future generations of physicists are bound to read these lectures with pleasure, benefiting from the lucid style that is so characteristic of Dyson's exposition.
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Advanced Quantum Mechanics

Advanced Quantum Mechanics

Freeman J Dyson

World Scientific Publishing Co Pte Ltd
2011
sidottu
Renowned physicist and mathematician Freeman Dyson is famous for his work in quantum mechanics, nuclear weapons policy and bold visions for the future of humanity. In the 1940s, he was responsible for demonstrating the equivalence of the two formulations of quantum electrodynamics — Richard Feynman's diagrammatic path integral formulation and the variational methods developed by Julian Schwinger and Sin-Itiro Tomonoga — showing the mathematical consistency of QED.This invaluable volume comprises the legendary lectures on quantum electrodynamics first given by Dyson at Cornell University in 1951. The late theorist Edwin Thompson Jaynes once remarked, “For a generation of physicists they were the happy medium: clearer and better motivated than Feynman, and getting to the point faster than Schwinger”.This edition has been printed on the 60th anniversary of the Cornell lectures, and includes a foreword by science historian David Kaiser, as well as notes from Dyson's lectures at the Les Houches Summer School of Theoretical Physics in 1954. The Les Houches lectures, described as a supplement to the original Cornell notes, provide a more detailed look at field theory, a careful and rigorous derivation of Fermi's Golden Rule, and a masterful treatment of renormalization and Ward's Identity.Future generations of physicists are bound to read these lectures with pleasure, benefiting from the lucid style that is so characteristic of Dyson's exposition.
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Advanced Quantum Mechanics

Advanced Quantum Mechanics

Freeman J Dyson

World Scientific Publishing Co Pte Ltd
2011
nidottu
Renowned physicist and mathematician Freeman Dyson is famous for his work in quantum mechanics, nuclear weapons policy and bold visions for the future of humanity. In the 1940s, he was responsible for demonstrating the equivalence of the two formulations of quantum electrodynamics — Richard Feynman's diagrammatic path integral formulation and the variational methods developed by Julian Schwinger and Sin-Itiro Tomonoga — showing the mathematical consistency of QED.This invaluable volume comprises the legendary lectures on quantum electrodynamics first given by Dyson at Cornell University in 1951. The late theorist Edwin Thompson Jaynes once remarked, “For a generation of physicists they were the happy medium: clearer and better motivated than Feynman, and getting to the point faster than Schwinger”.This edition has been printed on the 60th anniversary of the Cornell lectures, and includes a foreword by science historian David Kaiser, as well as notes from Dyson's lectures at the Les Houches Summer School of Theoretical Physics in 1954. The Les Houches lectures, described as a supplement to the original Cornell notes, provide a more detailed look at field theory, a careful and rigorous derivation of Fermi's Golden Rule, and a masterful treatment of renormalization and Ward's Identity.Future generations of physicists are bound to read these lectures with pleasure, benefiting from the lucid style that is so characteristic of Dyson's exposition.
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Dare to Believe God, Vol 2

Dare to Believe God, Vol 2

Freeman Witherspoon

Unmatched Publishing Inc.
2023
pokkari
Faith is one of the essentials of life. However, the challenge is how to be able to appropriate it to access the supernatural realm. Many people understand the concept of faith or know about faith, but they are not benefiting from it because they don't know how to appropriate it to get miracles or get God working for them. The concept of faith is what is going to create the manifestation of the divine. God has always wanted to work for us, and that is why He invited each of us to Himself. This invitation comes because He wants to do business with us. The business of faith is the only way in which one can receive miracles from God.- (From the introduction)In this book, "Dare to Believe God," Freeman Witherspoon, a military veteran, invites you to a dimension of believing God to take a new realm of life-a life of increase and influence. He unravels the power of faith. He brings you to understand: God can be trustedWithout faith, nothing happensGod has got you covered, and you have to believe Him.Challenges can be overcome through faithGreat things can be achieved through faithHow to condition your mind to believe the impossible.Filled with spiritual and inspirational thoughts. All messages shared here are thought-provoking. The goal is to challenge you to believe in God for the glorious future awaiting you in Christ and challenge you to accomplish incredible things.
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