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1000 tulosta hakusanalla Mario Rodriguez

An Integrated Approach for Added-Value Products from Lignocellulosic Biorefineries

An Integrated Approach for Added-Value Products from Lignocellulosic Biorefineries

Alírio Egídio Rodrigues; Paula Cristina de Oliveira Rodrigues Pinto; Maria Filomena Barreiro; Carina Andreia Esteves da Costa; Maria Inês Ferreira da Mota; Isabel Fernandes

Springer Nature Switzerland AG
2019
nidottu
This book offers the state of the art on the progress and accomplishments of 25 years of research at the Associate Laboratory LSRE-LCM - Laboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials on lignin conversion to value-added products and their downstream separation. The first valorisation pathway presented for lignin is its partial depolymerisation by oxidation for the production of low molecular weight phenolic compounds, such as vanillin and syringaldehyde, and the second one is the lignin application as macromonomer for polyurethane synthesis. In this book, the authors present the integration of these two valorisation pathways as an exclusive vision of LSRE-LCM resulting from hands-on experience on reaction and separation processes: the integrated process for lignin valorisation. In this perspective, the lignin is oxidized to simultaneously produce syringaldehyde and vanillin, and the obtained by-products to produce a polyolfor lignin-based polyurethanes, completing the lignin value chain. On the perspective of pulp mill-related biorefineries, a valorisation route for eucalyptus bark is also presented, focusing on LSRE-LCM experience on extraction and separation of bioactive polyphenols, giving some insights about further integration of extracted bark on biorefining operations.
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An Integrated Approach for Added-Value Products from Lignocellulosic Biorefineries

An Integrated Approach for Added-Value Products from Lignocellulosic Biorefineries

Alírio Egídio Rodrigues; Paula Cristina de Oliveira Rodrigues Pinto; Maria Filomena Barreiro; Carina Andreia Esteves da Costa; Maria Inês Ferreira da Mota; Isabel Fernandes

Springer International Publishing AG
2018
sidottu
This book offers the state of the art on the progress and accomplishments of 25 years of research at the Associate Laboratory LSRE-LCM - Laboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials on lignin conversion to value-added products and their downstream separation. The first valorisation pathway presented for lignin is its partial depolymerisation by oxidation for the production of low molecular weight phenolic compounds, such as vanillin and syringaldehyde, and the second one is the lignin application as macromonomer for polyurethane synthesis. In this book, the authors present the integration of these two valorisation pathways as an exclusive vision of LSRE-LCM resulting from hands-on experience on reaction and separation processes: the integrated process for lignin valorisation. In this perspective, the lignin is oxidized to simultaneously produce syringaldehyde and vanillin, and the obtained by-products to produce a polyolfor lignin-based polyurethanes, completing the lignin value chain. On the perspective of pulp mill-related biorefineries, a valorisation route for eucalyptus bark is also presented, focusing on LSRE-LCM experience on extraction and separation of bioactive polyphenols, giving some insights about further integration of extracted bark on biorefining operations.
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European Perspectives on Poverty and Poor People Pobreza E Perspectivas Europeias

European Perspectives on Poverty and Poor People Pobreza E Perspectivas Europeias

Fernanda Rodrigues; Ticu Constantin; Rudy Van den Hoven; Maria Nunes

Peter Lang GmbH
2005
nidottu
In this book, conceptions of, and perspectives on, poverty and poor people are presented with consequences for the field of measurement and evaluation. It is in this context that one analyses the emergence, development and relevance of social intervention directed at the problem of poverty and at the population suffering from it. Some policies and measures of supranational bodies are approached, with the aim of relating the dimension of the problem with the nature of the public strategies designed to combat poverty. Neste livro apresentam-se e debatem-se, em primeiro lugar, concepcoes e perspectivas sobre a pobreza e pessoas em situacao de pobreza e empobrecimento, com consequencias para o campo da sua medicao e avaliacao. E neste contexto que se analisa a emergencia, desenvolvimento e actualidade das intervencoes sociais dirigidas para o problema da pobreza e populacao por ela atingida. Algumas politicas e medidas da iniciativa de entidades supranacionais sao tambem abordadas, visando-se e sugerindo-se relacionar a dimensao do problema com a natureza das estrategias politicas para o seu enfrentamento."
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New antifungal compounds targeting TRR1 of Paracoccidioides genus

New antifungal compounds targeting TRR1 of Paracoccidioides genus

Ana Karina Rodrigues Abadio; Bernard Maigret; Maria Sueli Soares Felipe

Editions Universitaires Europeennes
2017
pokkari
The prevalence of invasive fungal infections (IFI) has increased steadily worldwide in the last few decades. Immunosuppressed patients present severe clinical forms of the infections, which are commonly fatal, and they are more susceptible to opportunistic fungal infections. IFI have been associated with high morbidity and mortality, partly because of the limitations of available antifungal therapies. The search for alternative therapies and/or the development of more specific drugs is a challenge that needs to be met. In silico analyses and manual mining selected 10 genes present in pathogenic fungi and absent in the human genome. We focused on TRR1 of Paracoccidioides lutzii that encodes for thioredoxin reductase. A computer-aided screening strategy against the TRR1 protein is presented here. From the molecules tested, 3 harbor inhibitory activity in antifungal assays against the pathogenic fungi. Corroborating these findings, the molecules have inhibitory activity against the purified recombinant enzyme TRR1 in biochemical assays. These results provide a promising technique to the development of new and innovative drugs.
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