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Multiple myeloma of the elderly in rheumatology

Multiple myeloma of the elderly in rheumatology

Afef Feki; Rim Akrout; Sofien Baklouti

Our Knowledge Publishing
2023
pokkari
Multiple myeloma is a malignant plasma cell proliferation that secretes a monoclonal immunoglobulin or a fragment of this immunoglobulin. The aim of this study is to specify the clinical, biological, radiological and therapeutic characteristics of MM in the elderly. A retrospective analysis of 51 patients with MM aged over 65 years and followed in a rheumatology department over a period of 22 years was made. The circumstances of discovery were dominated by bone pain (70.5%) and general syndrome (50% of cases). At the time of diagnosis, hematological complications such as anemia were more frequent in this setting than in others. The majority of patients (90.1%) were classified as Salmon and Durie stage III. Our patients were treated according to 3 protocols depending on the recruitment period. When following our patients, the majority were lost to follow-up. The causes of death were dominated by chemotherapy toxicity. Thus, the therapeutic management of these patients requires an evaluation of the tolerance/efficacy ratio to ensure an adequate quality of life.
Multiple nationality

Multiple nationality

Constant Mutamba

Our Knowledge Publishing
2023
pokkari
This book constitutes such a sober contribution to the evolution of Congolese nationality law, and at the same time is of significant importance, because it intervenes in a field that has not yet been scientifically explored in the DRC.Its main aim is to challenge the consciences of Congolese on the need to adapt Congolese nationality law to the realities of the day, in order to exfiltrate it from the decalcomania in which it finds itself today. Congolese nationality has been the subject of much debate. The most recent is the one raised by Mr. Noel TSHIANI, who proposed the locking of access to certain high positions, to be reserved only for Congolese fathers and mothers. Proposal contested by another segment of the population.