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1000 tulosta hakusanalla Maria W. Taylor

Oxytocin in der kardiovaskulären Homöostase

Oxytocin in der kardiovaskulären Homöostase

Valney Mara Gomes Conde; Domingos L W Picanço Diniz

Verlag Unser Wissen
2023
pokkari
Oxytocin (OT), historisch bekannt f r seine Wirkung auf das Fortpflanzungssystem, kann auch zur Regulierung der kardiovaskul ren und Wasser-Elektrolyt-Hom ostase beitragen. OT wird im supraoptischen und paraventrikul ren Kern des Hypothalamus produziert und von neuralen Terminals der Hypophysenhinterwand ins Plasma freigesetzt. In zahlreichen Studien wurden jedoch auch extrazerebrale Orte der OT-Produktion identifiziert, darunter das Herz und das Gef endothel. Die Aktivierung seiner Rezeptoren auf Endothelzellen sowie im hypothalamischen/hypophys ren und kardialen System kann zur Produktion von Stickstoffmonoxid (NO) f hren. Wir wollten die Rolle von NO bei der Regulierung der OT-stimulierten Sekretion von atrialem natriuretischem Peptid (ANP) in Prim rkulturen von embryonalen Kardiomyozyten der Maus berpr fen. Zu diesem Zweck wurden Herzen von Balb-C-Mausembryonen, die 19 bis 21 Tage alt waren, isoliert und f r Tests mit OT und anderen st renden Substanzen f r die Synthese von NO und cGMP, seinem zweiten Botenstoff, kultiviert.
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Oxytocin in Cardiovascular Homeostasis

Oxytocin in Cardiovascular Homeostasis

Valney Mara Gomes Conde; Domingos L W Picanço Diniz

Our Knowledge Publishing
2023
pokkari
Oxytocin (OT), historically known for its actions on the reproductive system, may also contribute to the regulation of cardiovascular and water-electrolyte homeostasis. OT is produced in the supraoptic and paraventricular nuclei of the hypothalamus and released into plasma from neural terminals of the posterior pituitary, however, many studies have identified extra-cerebral sites of OT production, including the heart and vascular endothelium. Activation of its receptors on endothelial cells, as well as in hypothalamic/hypophyseal and cardiac systems, may result in nitric oxide (NO) production. We aimed to verify the role of NO in the regulation of OT-stimulated atrial natriuretic peptide (ANP) secretion in primary culture of mouse embryonic cardiomyocytes. For this, we used hearts from Balb C mouse embryos, 19 to 21 days old intrauterine, were isolated and cultured for assays with OT and other interfering substances in the synthesis of NO and cGMP its second messenger.
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L'ocytocine dans l'homéostasie cardiovasculaire

L'ocytocine dans l'homéostasie cardiovasculaire

Valney Mara Gomes Conde; Domingos L W Picanço Diniz

Editions Notre Savoir
2023
pokkari
L'ocytocine (OT), historiquement connue pour ses actions sur le syst me reproducteur, peut galement contribuer la r gulation de l'hom ostasie cardiovasculaire et hydro lectrolytique. L'ocytocine est produite dans les noyaux supraoptique et paraventriculaire de l'hypothalamus et lib r e dans le plasma par les terminaisons neurales de l'hypophyse post rieure, mais de nombreuses tudes ont identifi des sites extra-c r braux de production d'ocytocine, notamment le coeur et l'endoth lium vasculaire. L'activation de ses r cepteurs sur les cellules endoth liales, ainsi que dans les syst mes hypothalamiques/hypophysaires et cardiaques, peut entra ner la production de monoxyde d'azote (NO). Nous avons cherch v rifier le r le du NO dans la r gulation de la s cr tion de peptide natriur tique auriculaire (ANP) stimul e par l'OT dans une culture primaire de cardiomyocytes embryonnaires de souris. Pour cela, nous avons utilis des coeurs d'embryons de souris Balb C, g s de 19 21 jours intra-ut rins, qui ont t isol s et cultiv s pour des tests avec OT et d'autres substances interf rentes dans la synth se de NO et de GMPc, son second messager.
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L'ossitocina nell'omeostasi cardiovascolare

L'ossitocina nell'omeostasi cardiovascolare

Valney Mara Gomes Conde; Domingos L W Picanço Diniz

Edizioni Sapienza
2023
pokkari
L'ossitocina (OT), storicamente nota per le sue azioni sul sistema riproduttivo, pu anche contribuire alla regolazione dell'omeostasi cardiovascolare e idrico-elettrolitica. L'OT prodotto nei nuclei sopraottico e paraventricolare dell'ipotalamo e rilasciato nel plasma dai terminali neurali dell'ipofisi posteriore; tuttavia, molti studi hanno identificato siti extra-cerebrali di produzione dell'OT, tra cui il cuore e l'endotelio vascolare. L'attivazione dei suoi recettori sulle cellule endoteliali, cos come nei sistemi ipotalamico/ipofisario e cardiaco, pu determinare la produzione di ossido nitrico (NO). Abbiamo voluto verificare il ruolo dell'NO nella regolazione della secrezione di peptide natriuretico atriale (ANP) stimolata da OT in colture primarie di cardiomiociti embrionali di topo. A tal fine, abbiamo utilizzato cuori di embrioni di topo Balb C, di 19-21 giorni di et intrauterina, isolati e messi in coltura per saggi con OT e altre sostanze interferenti nella sintesi di NO e cGMP, il suo secondo messaggero.
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Mestring av rus- og psykiske problemer

Mestring av rus- og psykiske problemer

Marit Holter; Bente Espeland; Rolf W. Gråwe

Tapir Akademisk Forlag
2009
nidottu
Dette er et gruppebasert, praktisk og strukturert trenings- og rehabiliteringsprogram for personer som har en psykisk lidelse og en ruslidelse samtidig (både alvorlige og mindre alvorlige lidelser). Som de andre programmene i serien På vei til et bedre liv, er også dette laget som et lærings- og mestringskurs. Flere nyere behandlingsstudier viser at det er mulig å hjelpe personer med psykiske lidelser og rusproblemer. Arbeidsbok.
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The Use of Words in Context

The Use of Words in Context

John W. Black; Cleavonne S. Stratton; Alan C. Nichols; Marian Ausherman Chavez

Kluwer Academic/Plenum Publishers
1985
sidottu
The Speech Situation is a term worn with age in the teaching of public speaking in America. That it is comprised of occasion, speaker, and topic is a gross oversimplification. It also includes challenge, anxiety, emotion, fear, responsibility, faults of memory, and instants of pride. Out of the circumstances arise an increase in heart rate, a change in blood pressure, an abnormal pattern of breathing, a noticeable build­ up in perspiration, and an ongoing evaluation. For students this may be merely a grade or perhaps a series of evaluative remarks, possibly addressed both to the speaker and the other participants, the audience. It may entail a replaying of a record of the speech, indeed a videotape. Most important is the lasting impression that remains with all of the participants. What of the vocabulary of the speaker under the circumstances of the speech situation? This speaker - in the major portions of this work we may say, "this young man" - has spent time seeking an appropriate topic. He has outlined a composition around a central idea or thesis. He has marshaled evidence, details. He has framed an opening paragraph. He has been admonished not to give an essay, but to strive for audience contact, interpersonal communication. He makes his audible approach through his vocabulary and accompanying phonology. Under the tension, the speaker repeats; he adds meaningless vocalizations in periods that might logically be pauses. There are slips of the tongue. At worst, failing, he withdraws to await another day.
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Menopause For Dummies

Menopause For Dummies

Marcia L. Jones; Theresa Eichenwald; Nancy W. Hall

John Wiley Sons Inc
2006
nidottu
A comprehensive and practical guide for women of all ages to gain a clear view of the physical, mental, and emotional changes related to menopause Although menopause is a natural and inevitable stage in every woman's life, its physical, mental, and emotional manifestations can vary greatly from one person to the next. Add the conflicting "expert" information about the benefits, risks, and side effects to which women are exposed on a daily basis, and it's easy to see many women find it difficult to make informed choices about how to deal with their menopausal symptoms. Authored by a team of acknowledged experts in treating menopausal symptoms, Menopause For Dummies provides you with all the information you need to stay in control every step of the way. In plain English, it explains the role menopause plays in a variety of common health problems, such as osteoporosis, stroke, and heart disease. It walks you through proven measures for minimizing your risk of developing complications, including diet and exercise, stress management, hormone replacement, and other techniques. And this no-nonsense guide gives you authoritative, up-to-the-minute coverage of: How to identify pre-menopause (perimenopause) and what it meansThe stages of menopauseHow menopause can affect your body, emotions, and libidoThe latest facts about hormone replacement therapyThe pros and cons of various alternative treatmentsThe best ways of handling hot flashesEasing symptoms with diet and exercisePreventing bone lossHelpful lifestyle changes This book has four top ten lists to provide even more ways of navigating the changes you'll experience throughout menopause—exposing common myths about menopause, giving you the scoop on medical tests you might need, kicking around ideas to kick-start or rejuvenate your exercise routine, and tempting you with fabulous healthy foods (because eating healthy doesn't have to be boring). Additionally, the book has a glossary and a list of resources to find more information about menopause, hormones, and related conditions. With Menopause For Dummies in your corner, you’ll have a kinder, gentler "change of life."
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The Hospice Choice

The Hospice Choice

Galen W. Miller; John J. Mahoney; Marcia Lattanzi-Licht

Touchstone
1998
pokkari
Hospice is the primary system to provide care for the terminally ill and their families. Warm, compassionate, and absolutely practical, this definitive resource from the National Hospice Organization will answer all your questions about hospice care and will show you how to make this comprehensive and flexible system work for you and your family. The Hospice Choice illustrates the gamut of situations dying people and their families may face and suggests ways to manage them. Throughout is information on the broad range of services hospice can provide: Physicians and Nursing Services: to help with care specifically designed to keep the patient comfortable and at home Counseling Services: to help families and patients sort out their needs and responses Respite Services: to allow caregivers needed breaks Bereavement Counseling: to provide support for surviving family members and significant others for as much as a full year after loss The Hospice Choicealso addresses sensitive issues like methods of payment, issues of ethnicity, the special problems raised by sudden death, and the realities of caregiver exhaustion. It will give you the concrete information, support, and encouragement that will help you make wise, compassionate decisions for yourself and for your loved ones.
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Inquiry In Education Set V 1&2

Inquiry In Education Set V 1&2

Mark W. Aulls; Bruce M. Shore; Marcia A.B. Delcourt

Routledge Member of the Taylor and Francis Group
2007
muu
First published in 2007.To be human is to inquire. However, inquiry is a process which of itself demands a very large succession of skills to proceed in growth from asking and answering questions of daily life to problem solving, to doing projects and investigations requiring substantial time commitments, to scholarly research in a specific domain. This set comprises if Inquiry in Education Volume I and II. Volume I focuses on The Conceptual Foundations for Research as a Curricular Imperative and Volume II looks at Overcoming Barriers to Successful Implementation.
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Beyond Return on Investment

Beyond Return on Investment

Pam W. Arlotto; Patricia C. Birch; Marla H. Crockett; Susan P. Irby; Pam Arlotto; Susan Irby

CRC Press
2019
nidottu
Beyond Return on Investment: Expanding the Value of Healthcare Information Technology, 2nd Edition this updated and revised edition provides lessons learned from healthcare IT adoption and the opportunity to drive value realization. From providing a basic primer on 'how-to' complete a Return on Investment analysis for a single project to developing a comprehensive program of value management to support the transition to high value healthcare, this book addresses emerging trends, practical approaches and measurement methods to help drive value. Beyond Return on Investment, 2nd Edition views IT as a strategic asset in the transformation of healthcare. Based on previous editions, this book updates and identifies the components of an integrated value management strategy including value driven decision-making culture, an integrated approach to strategy development, a value based governance model, a process that defines business case development through ROI analysis, value measurement and value scorecard development. New chapters in this addition include a Framework for Value Management, validating vendor defined value and ROI, and new methods for realizing value.
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Beyond Return on Investment

Beyond Return on Investment

Pam W. Arlotto; Patricia C. Birch; Marla H. Crockett; Susan P. Irby; Pam Arlotto; Susan Irby

CRC Press
2019
sidottu
Beyond Return on Investment: Expanding the Value of Healthcare Information Technology, 2nd Edition this updated and revised edition provides lessons learned from healthcare IT adoption and the opportunity to drive value realization. From providing a basic primer on 'how-to' complete a Return on Investment analysis for a single project to developing a comprehensive program of value management to support the transition to high value healthcare, this book addresses emerging trends, practical approaches and measurement methods to help drive value. Beyond Return on Investment, 2nd Edition views IT as a strategic asset in the transformation of healthcare. Based on previous editions, this book updates and identifies the components of an integrated value management strategy including value driven decision-making culture, an integrated approach to strategy development, a value based governance model, a process that defines business case development through ROI analysis, value measurement and value scorecard development. New chapters in this addition include a Framework for Value Management, validating vendor defined value and ROI, and new methods for realizing value.
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Pedophilia and Exhibitionism

Pedophilia and Exhibitionism

J.W. Mohr; R.E. Turner; Marian Jerry

UNIVERSITY OF TORONTO PRESS
1964
pokkari
The primary purpose of this book is to explore the nature of two forms of sexual behaviour which represent the majority of sexual offences coming to the attention of the courts. Special emphasis is given to the social significance of the deviant behaviour. The material presented has emerged primarily from empirical study and research on cases referred to the Forensic Clinic of the Toronto Psychiatric Hospital, established by the Government of Ontario in affiliation with the Department of Psychiatry of the University of Toronto. The Clinic was established specifically to assist the courts in the assessment and treatment of offenders. The choice of exhibitionism and pedophilia for consideration was made on purely quantitative grounds, and quantitative considerations remained a leading factor throughout the study. The bizarre and exotic phenomena of sexual behaviour too frequently overshadow the far greater amount of human misery which can be observed daily in our lower courts. All too often the problems of the sexual offender are seen in terms of isolated but highly publicized cases of atrocities with the result that the minor sex offender (who is by far in the majority) tends to be seen as a potential fiend and maniac. In the absence of a clear picture of the natural history of the various sexual deviations and resulting offences, predictions of the subsequent behaviour of an offender are at best tenuous. In reviewing the literature on pedophilia and exhibitionism, the authors found no systemic account of pedophilia, and only one book specifically devoted to exhibitionism. It therefore became necessary to expand their own researches into a handbook on the sexual offences arising out of the two deviations. Comparative data from the literature has been incorporated. The organization of this material posed many problems because of the diversity of definitions, samples, and classifications used in various studies, and this diversity reflects the great need for investigation of the subject if diagnosis, sentencing, and treatment are to be soundly based. In his Foreword, Professor Kenneth G. Gray points to the usefulness of this study in many areas: "Psychiatrists will find a great deal of information about selection of cases for treatment. The prognosis for sex offenders is generally good but it is better from some categories of offenders than others. With rare exceptions, the sex offender is not mentally ill or mentally defective except with regard to his sexual deviation ... Judges and magistrates will find here information that is of value in sentencing a sexual offender. Research has produced data which provide a reasonably accurate prediction about the likelihood of recurrence ... Social workers and educators will be particularly interested in the description of sexual molestation of young children. They will be able to convey such information to parents whose child has been assaulted and will be better able to assess the effects on the child and to deal with them."
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The Use of Words in Context

The Use of Words in Context

John W. Black; Cleavonne S. Stratton; Alan C. Nichols; Marian Ausherman Chavez

Springer-Verlag New York Inc.
2013
nidottu
The Speech Situation is a term worn with age in the teaching of public speaking in America. That it is comprised of occasion, speaker, and topic is a gross oversimplification. It also includes challenge, anxiety, emotion, fear, responsibility, faults of memory, and instants of pride. Out of the circumstances arise an increase in heart rate, a change in blood pressure, an abnormal pattern of breathing, a noticeable build­ up in perspiration, and an ongoing evaluation. For students this may be merely a grade or perhaps a series of evaluative remarks, possibly addressed both to the speaker and the other participants, the audience. It may entail a replaying of a record of the speech, indeed a videotape. Most important is the lasting impression that remains with all of the participants. What of the vocabulary of the speaker under the circumstances of the speech situation? This speaker - in the major portions of this work we may say, "this young man" - has spent time seeking an appropriate topic. He has outlined a composition around a central idea or thesis. He has marshaled evidence, details. He has framed an opening paragraph. He has been admonished not to give an essay, but to strive for audience contact, interpersonal communication. He makes his audible approach through his vocabulary and accompanying phonology. Under the tension, the speaker repeats; he adds meaningless vocalizations in periods that might logically be pauses. There are slips of the tongue. At worst, failing, he withdraws to await another day.
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