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Associazione tra virus JC e BK e regolatore della chinasi dipendente dalla ciclina

Associazione tra virus JC e BK e regolatore della chinasi dipendente dalla ciclina

Dhuha Abdullah Kadhim Al-Dhuwayhiry; Saif Jabbar Yasir

Edizioni Sapienza
2023
pokkari
Questo studio stato concepito come uno studio trasversale. stato coinvolto un numero totale di 94 campioni di carcinoma a cellule renali fissati in formalina e inclusi in paraffina (55 maschi e 39 femmine, di et compresa tra 18 e 80 anni). I dati sono stati raccolti dai registri dei laboratori istopatologici dell'Al-Sadder Teaching Hospital e di alcuni laboratori istopatologici privati del governatorato di Najaf nel periodo compreso tra dicembre 2018 e maggio 2019, utilizzando la tecnica molecolare (reazione a catena della polimerasi) per la rilevazione del DNA di BKPyV e JCPyV e la tecnica di immunoistochimica (IHC) per la rilevazione delle proteine di espressione dei marcatori dei regolatori della chinasi dipendente dalla ciclina (KAP o CDKN3 e Cyclin E1).I risultati attuali della tecnica di immunoistochimica (IHC) hanno mostrato una maggiore percentuale di positivit del marcatore KAP o CDKN3 65 (69,15% su 94 tessuti) e una minore percentuale di positivit del marcatore Cyclin E1 13 (13,83% su 94 tessuti).
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Associação dos Vírus JC e BK e do Regulador da Quinase Dependente de Ciclina

Associação dos Vírus JC e BK e do Regulador da Quinase Dependente de Ciclina

Dhuha Abdullah Kadhim Al-Dhuwayhiry; Saif Jabbar Yasir

Edicoes Nosso Conhecimento
2023
pokkari
O presente estudo foi concebido como um estudo transversal. Foram inclu dos 94 fragmentos de carcinoma de c lulas renais fixados em formalina e inclu dos em parafina (55 homens e 39 mulheres, com idades compreendidas entre os 18 e os 80 anos). Os dados foram recolhidos a partir de registos de laborat rios histopatol gicos do Hospital Universit rio Al-Sadder e de alguns laborat rios histopatol gicos privados na prov ncia de Najaf durante o per odo de dezembro de 2018 a maio de 2019, utilizando a t cnica molecular (rea o em cadeia da polimerase) para a dete o de ADN para BKPyV e JCPyV, e a t cnica de imuno-histoqu mica (IHC) para detetar a express o de prote nas de marcadores de reguladores da quinase dependentes da ciclina (KAP ou CDKN3 e ciclina E1).Inicialmente, estes casos s o examinados histopatologicamente atrav s da colora o de hematoxilina e eosina (H&E), que foi efectuada por um histopatologista consultor para garantir a exist ncia de carcinoma das c lulas renais. Os resultados actuais da t cnica de imunohistoqu mica (IHC) mostraram que existia uma percentagem positiva mais elevada do marcador KAP ou CDKN3 65 (69,15% em 94 tecidos), enquanto existia uma percentagem positiva mais baixa do marcador Cyclin E1 13 (13,83% em 94 tecidos).
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Le virus JC chez les patients ayant subi une transplantation rénale

Le virus JC chez les patients ayant subi une transplantation rénale

Ali Mohamed Badri; Khalid A Enan

Editions Notre Savoir
2023
pokkari
Le virus John Cunningham (JCV) est un membre de la famille des Polyomaviridae, qui comprend le virus BK et le SV40. Le nom de polyome fait r f rence la capacit de cet organisme produire des tumeurs dans de nombreux organes diff rents. Ce sont des virus non envelopp s avec des capsides icosa driques et des g nomes d'ADN double brin circulaires de petite taille, les g nomes ayant une taille de 5 kb. Les h tes naturels des polyomavirus sont les humains, les autres primates, les rongeurs, les lapins et les oiseaux.
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Le p'tit Dico de JC

Le p'tit Dico de JC

Jean-Claude Bramly

Books on Demand
2021
pokkari
Taquiner les mots, les titiller... Jouer avec eux pour mieux se jouer d'eux. Leur faire dire ce qu'ils ne veulent pas toujours dire, tout en le disant quand m me, quand ce n'est pas le contraire Me suis-je bien fait comprendre ? Heu... pas s r Je reconnais que moi-m me; j'ai eu du mal... Bref: Un p'tit dico pas tout fait comme les autres...
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2188 Apr. Jc - Le Monde Sous Le Grand Califat: E Pluribus Umma

2188 Apr. Jc - Le Monde Sous Le Grand Califat: E Pluribus Umma

D. Leitsack

Exemplum Publishing LLC
2012
nidottu
Le Cheik Assam de l'Ameristan a recrut Al Kansii pour pr parer son assaut contre le Conseil du Peuple de l'Empire des Han. Aux alentours de 2188 l'Empire est la seule puissance de quelque importance dans un monde o tout a t soumis au Grand Califat. Le Conseil a par contre parmi ses membres Yu Lin, un scientifique de g nie aux ambitions politiques sans bornes. Est-ce-que Yu Lin pourra, avec l'aide de la belle et nigmatique Li Li, d faire l'Ange de la Mort, une arme de science fiction bas e sur les principes de la science quantique, effet tunnel et intrication, et utilisant des faisceaux de neutrinos? Des questions essentielles et contemporaines de religion et de politique qui font partie d'un d bat longuement d sont greff es aux concepts myst rieux de la physique quantique dans cette histoire fascinante - un conte des 'Mille et Une Nuits' dont l'action se passe en 2188. travers des jeux de mots entre plusieurs langues et parfois m me d'un humour raffin , le r cit porte Al Kansii dans plusieurs continents - Washington, Paris, Kandahar, les d serts de Taklimaklan et de Gobi, la Mongolie et la Mandchourie et d'autres lieux exotiques - et le fait s'interroger sur le sens de sa mission, et la signification du Temps. R ussira-t-il ? Est-ce qu'il survivra ? Est-ce qu'il nous le dira ? La th orie quantique est ici extrapol e au domaine de l'esprit humain pour atteindre les profondeurs de notre conscience et la survie de la pens e apr s la mort et sa transmission en dehors du cerveau, une th se qui laisse le lecteur r veur sinon boulevers . Et pendant qu'Al Kansii poursuit cette mission, la force paramilitaire ancr e dans l'Antarctique et fond e sur les principes des Chevaliers du Temple des si cles pass s pourra-t-elle miner le Califat ? Cet essai intellectuel et ambitieux pr sente une th se agressive mais n anmoins essentielle, la conqu te des peuple et la fin des civilisations, une th se qui exerce chez le lecteur une sensation d'inqui tude, parfois m me de r signation et ultimement de douce m lancolie - la derni re partie, fort mouvante, renvoie a une vision altruiste et conciliatrice qui nous laisse esp rer un monde meilleur. Politique. Histoire. Religion. Science et Fiction. M taphysique. Philosophie. "Un roman provocateur et franchement exceptionnel."
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Le différend entre César et le Sénat (59-49 av JC)

Le différend entre César et le Sénat (59-49 av JC)

Paul Guiraud

Books on Demand
2021
pokkari
Quand C sar revint d'Espagne, en 60, avec le dessein de briguer le consulat, Pomp e et Crassus taient les deux principaux personnages de Rome. Ils poss daient l'un et l'autre d'immenses richesses; leur client le tait tr s nombreuse, et beaucoup de villes, en Italie et au dehors, les reconnaissaient pour patrons. Ils avaient exerc de grands commandements, et leur gloire militaire, sans tre gale, attirait sur eux tous les regards. La majorit du s nat, il est vrai, leur tait hostile; mais cette hostilit m me leur assurait l'appui des chevaliers que les fautes de Caton et de ses amis avaient r cemment d tach s du parti s natorial; les soldats qui avaient servi sous leurs ordres leur taient d vou s; et la pl be Rome s'inclinait toujours devant ceux dont elle sentait la force. Comme les comices lectoraux d pendaient d'eux, C sar avait besoin de leur protection pour arriver au consulat. Il ne faut pas croire, en effet, qu'il e t d j la puissance que quelques historiens lui ont attribu e; les contemporains taient loin de le placer au m me niveau que Crassus et Pomp e. On vantait sa noble naissance, sa g n rosit , son loquence; on le savait ambitieux, hardi, peu scrupuleux dans le choix des moyens peu soucieux de la l galit , capable de tout oser et de tout entreprendre; on lui soup onnait les qualit s d'un chef de parti; on craignait qu'il ne se port t l'h ritier des Gracques. Mais les talents militaires et politiques qui ont fait de lui un grand g n ral et un grand homme d'Etat n'avaient pas encore eu l'occasion de se montrer...
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The Cards I Was Dealt the Hand That I Played: The Life of Jc Riley

The Cards I Was Dealt the Hand That I Played: The Life of Jc Riley

Joel C. Riley; Holly L. O'Connor

Independently Published
2018
nidottu
This is the story of Joel Christopher Riley. He was one of seven children who was taken away from his mother as a child and lived in five foster homes. He lived through abuse and neglect, became a father, joined the Marines, fought in Iraq, was other than honorably discharged and suffers from Post -Traumatic Stress Disorder. His unusual life is filled with struggles, bad behavior, triumphs, and humorous, sad and traumatic events. He and his mother, Holly O'Connor, wrote the book together. They want readers to understand the severe disadvantages that some children have growing up and help give hope to those in similar difficult situations. Joel was taken away from his drug addicted mother at the age of two. He came to live with the O'Connors when he was 13, after he had been in four different foster homes. He was a mess and terribly difficult to deal with. Joel could not believe someone would take him in, love him and really care about him. He did not trust anybody and would not let anyone into his world to help him. He put up a wall and refused to listen. The family stuck together because of the amazing strength and values of his father, Paul O'Connor who has strong religious convictions and a never give up attitude. The family grew tremendously with the experience of living together and becoming a real family. They learned how to love, care, understand and forgive under some of the most difficult circumstances and wanted share some of their experiences with the readers.
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La Péninsule d'Oman de la fin de l'Age du Fer au début de la période sassanide (250 av. - 350 ap. JC)

La Péninsule d'Oman de la fin de l'Age du Fer au début de la période sassanide (250 av. - 350 ap. JC)

Michel Mouton

BAR Publishing
2008
nidottu
This thesis, written fifteen years ago, has its own reputation; and it is because it has been so often refrred to that it is now published, unchanged but with a supplementary bobliography. The discussion of the finds from the two sites of Mleiha and ed-Dur is important both locally and regionally, and to wider historical questions such as the population and culture of pre-Islamic Arabia, the spread of Mediterranean culture and the general development of Arabia in the centuries before Islam.
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Beast

Beast

Jc

Createspace Independent Publishing Platform
2015
nidottu
Tarik Bush, also known as Beast, is a street enforcer with a drug dynasty in Augusta, Georgia. He is feared by most and respected by all, always seeming to run the streets with smarts and brutal force. But, he's growing tired of his way of life and decides he wants out, and although he's ready to throw in the towel, he still knows sleeping with the Drug Boss' girl is a no no. Unable to resist temptation, his actions will cause a domino effect that nearly takes out his whole crew. Now, in order to save the people he cares for, even the love of his life, the Boss' girl, he must put his life on the line as the predator becomes the prey. Will Beast be able to walk away from the life he's created over the years or will that life be the very demise of him?
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As Long As You Both Shall Live

As Long As You Both Shall Live

Jc

Createspace Independent Publishing Platform
2015
nidottu
Angela perfect love life came to an abrupt end when the love of her life was in a life changing car accident. Her life also changed and challenged her vows "As Long As You Both Shall Live". Stepping out of the marriage could have serious backlashes to the point of somebody getting... BURNED
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Divine Contradiction

Divine Contradiction

Jc Beall

Oxford University Press
2023
sidottu
Building on his paradigm-shifting work on the incarnation in The Contradictory Christ (OUP, 2021), Jc Beall extends a robust contradictory theology with an account of the trinity. Throughout the history of the Christian church, heretics, apophatics, mystics, atheists, and many others have long proclaimed that the doctrine of the trinity - one of the central doctrines of the Christian faith - is contradictory. In this work, Beall agrees; however, as Beall convincingly argues, one needn't abandon orthodoxy, play language games, inflate one's metaphysics, nor abandon the standard faith in the face of such divine contradiction. Instead, one can accept central axioms of the trinity at face value and, with a suitable account of logical entailment, accept the 'contradictory truths' thereby entailed. With the clarity and precision that only a logician could provide, Beall provided theology and the Christian church in general with a very simple and viable (and arguably correct) model of divine reality. Unlike the vast number of theologians and philosophers before him, Beall rejects the quest for a logically consistent account of divine reality. The triune god (viz., God) is truly and fully described only via contradiction. As such, attempts to remove the contradiction are attempts to remove truths of God.
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