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Molecular Basis of Insulin Action

Molecular Basis of Insulin Action

Michael P. Czech

Springer-Verlag New York Inc.
2012
nidottu
One day, in a moment of weakness, I fell prey to the temptation to organize and edit this volume on the mechanism of insulin action. The major reason for attempting to resist, of course, is the amazing speed at which advances are being made in this field. The usefulness of books such as this is often quickly compromised by new findings obtained during and just after publication. Happily for the contributors to this volume and myself, this unfortunate fate does not appear to be in store for us. New and important findings will undoubtedly continue to flow in this field during the next few years, but I believe this will increase rather than decrease the usefulness of this volume. As a matter of fact, as we go to press, I am delighted both that I was tempted and that I failed to resist. There are two basic reasons for my enthusiasm about this book, and they both relate to this issue of timeliness. First, each of the contributors has had an opportunity to update the scientific content of the various chapters only a few months before actual publication of this volume. The material presented in this volume is, at publication, contemporary with the current original literature. This volume thus provides an ex­ cellent framework for assessing new discoveries in this field for some time to come.
American Bards

American Bards

Whitley Edward

The University of North Carolina Press
2014
nidottu
Walt Whitman has long been regarded as the quintessential American bard, the poet who best represents all that is distinctive about life in the United States. Whitman himself encouraged this view, but he was also quick to remind his readers that he was an unlikely candidate for the office of national poet, and that his working-class upbringing and radical take on human sexuality often put him at odds with American culture. While American literary history has tended to credit Whitman with having invented the persona of the national outsider as the national bard, Edward Whitley recovers three of Whitman's contemporaries who adopted similar personae: James M. Whitfield, an African American separatist and abolitionist; Eliza R. Snow, a Mormon pioneer and women's leader; and John Rollin Ridge, a Cherokee journalist and Native-rights advocate. These three poets not only provide a counterpoint to the Whitmanian persona of the outsider bard, but they also reframe the criteria by which generations of scholars have characterized Whitman as America's poet. This effort to resituate Whitman's place in American literary history provides an innovative perspective on the most familiar poet of the United States and the culture from which he emerged.
The Bars Are Ours

The Bars Are Ours

Lucas Hilderbrand

DUKE UNIVERSITY PRESS
2023
sidottu
Gay bars have operated as the most visible institutions of the LGBTQ+ community in the United States for the better part of a century, from before gay liberation until after their assumed obsolescence. In The Bars Are Ours Lucas Hilderbrand offers a panoramic history of gay bars, showing how they served as the medium for queer communities, politics, and cultures. Hilderbrand cruises from leather in Chicago and drag in Kansas City to activism against gentrification in Boston and racial discrimination in Atlanta; from New York City’s bathhouses, sex clubs, and discos and Houston’s legendary bar Mary’s to the alternative scenes that reimagined queer nightlife in San Francisco and Latinx venues in Los Angeles. The Bars Are Ours explores these local sites (with additional stops in Denver, Detroit, Seattle, Philadelphia, Minneapolis, and Orlando as well as Wisconsin, Pennsylvania, and Texas) to demonstrate the intoxicating---even world-making---roles that bars have played in queer public life across the country.
The Bars Are Ours

The Bars Are Ours

Lucas Hilderbrand

DUKE UNIVERSITY PRESS
2023
pokkari
Gay bars have operated as the most visible institutions of the LGBTQ+ community in the United States for the better part of a century, from before gay liberation until after their assumed obsolescence. In The Bars Are Ours Lucas Hilderbrand offers a panoramic history of gay bars, showing how they served as the medium for queer communities, politics, and cultures. Hilderbrand cruises from leather in Chicago and drag in Kansas City to activism against gentrification in Boston and racial discrimination in Atlanta; from New York City’s bathhouses, sex clubs, and discos and Houston’s legendary bar Mary’s to the alternative scenes that reimagined queer nightlife in San Francisco and Latinx venues in Los Angeles. The Bars Are Ours explores these local sites (with additional stops in Denver, Detroit, Seattle, Philadelphia, Minneapolis, and Orlando as well as Wisconsin, Pennsylvania, and Texas) to demonstrate the intoxicating---even world-making---roles that bars have played in queer public life across the country.
Random Bars

Random Bars

Blake Wilder

Outskirts Press
2017
pokkari
This eclectic anthology of poems are the brainchild of an authentic B-Boy, inspired by thirty five years of revolutionary's in spoken words such as The Last Poets, Rakim, KRS-1, Tupac, Nas, and Saul Williams. In Random Bars there is a militancy of Pro-Black thought that still maintains a reflection of inclusion without compromise. The author is a descendant of a German-Irish mother, and an African-American father who was born a sharecropper in Mississippi. Through these lenses the author, Blake Wilder, gives a passionate display of word play narrating an unorthodox perspective of multiculturalism. Random Bars is an amazing mix of poetic verse with the dynamic influence of the generation X hip-hop culture. It is an intelligent collection that discusses many facets of societal causes and effects, while giving its reader a glimpse into the author's conscientious depths. Throughout Random Bars there are numerous historical references that expose the hypocrisy of the everyday world we exist in, many of which are composed from a first person observation. The impact of each piece is singular, but part of a whole, that shares the experiences of those that have succeeded, but still exist on the margins.
Pens & Bars: Revised

Pens & Bars: Revised

Richard Jones

Createspace Independent Publishing Platform
2013
nidottu
Revised from the original on the advice from readers this book of poetry shoud be even better to read than before.Partly written whilst in prison whilst learning to read and write, also on the way to achieving my diploma with the open university - this book includes several award winning poems.Hopefully you will give it a go and enjoy it as much as I enjoyed writing it - THANKS.
Molecular Basis of Human Cancer

Molecular Basis of Human Cancer

Springer-Verlag New York Inc.
2013
nidottu
During May 21-June 1 1990, the eleventh course of the International School of Pure and Applied Biostructure, a NATO Advanced Study Institute, was held at the Ettore Majorana Center for Scientific Culture in Erice, Italy, co-sponsored by the Italian Ministry of Universities and of Scientific and Technological Research, the North Atlantic Treaty Organization, the Italian National Research Council, the Sicilian Regional Government and Technobiochip. The subject of the course was "Molecular Basis of Human Cancer" with participants selected worldwide from 15 different countries. The purpose of the course was to address, in a tutorial and structural fashion, the molecular basis of human cancer, including the mechanism of signal transduction in mammalian cells, the genetic mechanism of malignant transformation in man, growth factors, hormone receptors, cell membrane and cytoskeleton, and DNA high order structure. The course had this as its major objective and the resulting book reflects it. The participants were exposed to a critical evaluation of current knowledge about cancer and to some of the key problems that remain as stumbling blocks to our eventual understanding of this important biological and medical problem. Through the media of formal and informal lectures, workshops, symposia and informal discussions, a select group of interested young and senior scientists were acquainted with many of the aspects of human cancer.
Molecular Basis for Therapy of AIDS-Defining Cancers
Cancer incidences increase in people living with HIV/AIDS. Over 2 million people currently live with HIV/AIDS in the US. This number will increase as HAART prolongs the average lifespan and as (at least in some states) the number of new HIV infections increase again. As this population ages their incidence rates for cancer will increase, as well. Recently, new rational targets for cancer therapy have emerged. But their application to the care of HIV+ patients is slow, because of concerns about the weakened immune status of the patients, because of possible drug interactions with HAART and because some of the AIDS defining cancer are rare.
Metabolic Basis of Obesity

Metabolic Basis of Obesity

Springer-Verlag New York Inc.
2014
nidottu
The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. Thanks to greatly enhanced research in the area, the discovery of pathways in the brain and peripheral organs that mediate energy homeostasis has provided a framework for understanding the biological basis of obesity. Metabolic Basis of Obesity adds an important new dimension to the growing literature on obesity by offering a comprehensive review of specifically how metabolic imbalance culminates in obesity. Developed by a team of expert authors, this important title discusses the principles of energy balance, genetics of body weight regulation, hormones and adipokines, and metabolic pathways in the brain, liver, muscle and fat, to name just several of the areas covered. The book also examines the connection between obesity and diabetes, cardiovascular disease and other complications. Current and future diagnostic and treatment strategies are also reviewed. Comprehensive and timely, Metabolic Basis of Obesity is an essential reference for understanding the burgeoning problem of obesity.
Genetic Basis for Respiratory Control Disorders
Bringing together top-level contributions on all aspects of the subject, this book provides an overview of the recent advances in the genetics of respiratory control in health and disease. It also shows how combined studies in humans and mouse models have helped to improve our understanding of the mechanisms that underlie genetically determined respiratory control disorders with the goal of developing new therapeutic interventions.
The Bards will Sing

The Bards will Sing

J. W. Kent

Createspace Independent Publishing Platform
2013
nidottu
Returning from the Northern Wastes, Fergus was dismayed to find that the Bards were indeed "singing his name", as he made a joyous reunion with his comrades of the TKT. His time on the plains of Valdenheim was short lived however, and given his first command, he was sent on a treacherous journey, south through the infamous Illesian swamps to the exotic Southern lands. There, amid the burning sands, an ancient horror awaited them... one that not only thirsted for their lives, but for their very souls.