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812 tulosta hakusanalla Rp Edwards

Propuesta para el manejo de RP

Propuesta para el manejo de RP

Longino Arvizu

Editorial Academica Espanola
2019
pokkari
La limpieza de autotanques asegura la pureza de la sustancia transportada e involucra la generaci n de aguas residuales y un alto riesgo de causar accidentes a quienes realizan esta actividad. Dada la necesidad de controlar los residuos generados en dicha limpieza y minimizar accidentes es conveniente esta investigaci n. El objetivo general es realizar una propuesta para el manejo de sustancias y residuos peligrosos dentro de una estaci n de limpieza y control de remanentes de autotanques que transportan hidrocarburos, considerando la NOM-019-SCT2/2004. Para lograrlo, se revisan reglamentos internacionales y mexicanos enfatizando en los requisitos t cnicos sobre las instalaciones de limpieza interior de autotanques, as como en los l mites m ximos permisibles de contaminantes en las descargas de aguas generadas en el proceso. Se identifica que la gasolina, diesel, turbosina y combust leo son los principales hidrocarburos transportados en M xico. Se describen procesos de limpieza de autotanques, constat ndose la ineficiencia en la vigilancia y aplicabilidad de la Norma en cuesti n.
Development and Validation of HPTLC and RP-UHPLC Method for Analysis

Development and Validation of HPTLC and RP-UHPLC Method for Analysis

Vansh Patel; Sudarshan Rajput; Jaykumar Rajput

Lap Lambert Academic Publishing
2024
pokkari
The present research focuses on the development and validation of two advanced chromatographic methods High-Performance Thin Layer Chromatography (HPTLC) and Reverse Phase Ultra High-Performance Liquid Chromatography (RP-UHPLC) for the qualitative and quantitative analysis of Punarnava (Boerhavia diffusa) in diuretic formulations. Punarnava is a well-known medicinal plant traditionally used for its diuretic properties. The methods were optimized to achieve high precision, accuracy, and sensitivity for the identification and quantification of bioactive compounds in complex herbal formulations.These validated methods offer reliable analytical tools for the standardization and quality control of diuretic formulations containing Punarnava, ensuring consistency and efficacy in pharmaceutical preparations.
The quantitative estimation of ivabradine by RP-HPLC in bulk drug

The quantitative estimation of ivabradine by RP-HPLC in bulk drug

Sunitha Pasupuleti; Mounika Nayan G

LAP Lambert Academic Publishing
2020
pokkari
A sensitive & selective RP-HPLC method has been developed & validated for the analysis of Ivabradine API. Further the proposed RP-HPLC method has excellent sensitivity, precision and reproducibility. The result shows the developed method is yet another suitable method for assay, purity which can help in the analysis of Ivabradine in different formulations. Satisfactory result was achieved with use of a mixture of Ammonium acetate buffer pH 6.0: Methanol (60:40 v/v) and symmetry C18 column (250 4.6mm, 5μm) was adopted for the analysis as it has provided a better elution of the analyte UV detection was carried out at 282 nm. The retention time was found to be 3.459 minutes. The linearity study for Ivabradine was found in concentration range of 12-28μg/ml and correlation coefficient (r) was found to be 0.999. The % mean recovery was found to be 100.07%. % RSD for repeatability was 0.0337.
Method Development and Validation of Zopiclone by RP-HPLC.

Method Development and Validation of Zopiclone by RP-HPLC.

Rahul Khaire

LAP Lambert Academic Publishing
2020
pokkari
A simple, sensitive, rapid and selective isocratic reversed phase High Performance Liquid Chromatographic (HPLC) method has been developed for Zopiclone from bulk drug using a mobile phase consisting mixture of Acetonitrile: Buffer (pH 2.8) (80:20v/v) Composition of buffer: (0.272gm in 200ml HPLC water and pH adjusted to 2.8 using ortho Phosphoric acid) at the flow rate of 1.0 mL/min. A Cosmosil C18 (250 cm x 4.6 mm, 5 μm) column was used as stationary phase.