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Multiple Stable States in Natural Ecosystems

Multiple Stable States in Natural Ecosystems

Peter Petraitis

Oxford University Press
2013
sidottu
One of the most interesting and vexing problems in ecology is how distinctly different communities of plants and animals can occur in the same ecosystem. The theory of these systems, known as multiple stable states, is well understood, but whether multiple stable states actually exist in nature has remained a hotly debated subject. Multiple Stable States in Natural Ecosystems provides a broad and synthetic critique of recent advances in theory and new experimental evidence. Modern models of systems with multiple stable states are placed in historical context. Current theories are covered in a rigorous fashion with the specific goal of identifying testable predictions about multiple stable states. The book provides a more synthetic, more critical, and broader analysis of multiple stable states in natural ecosystems than any previous review. By making the theory more transparent and the analysis of the evidence more comparative, the book broadens the discussion about multiple stable states, leading to a more general consideration of the interplay between theory and experiment in community ecology and environmental management. This accessible research monograph will be suitable for graduate students taking courses in community ecology, theoretical ecology, and restoration ecology. It will also be a valuable reference for professional ecologists and environmental managers requiring a concise overview of the topic.
Multiple Sclerosis

Multiple Sclerosis

Neil Scolding; Alastair Wilkins

Oxford University Press
2012
nidottu
Multiple sclerosis is the most common neurological cause of debilitation in young people; it affects approximately 85,000 people in the UK, 400,000 people in the US and approximately 2.5 million people worldwide. The disease commonly manifests in the second or third decade of life, and in most cases it leads to progressive disability, which explains its enormous impact on the economy (estimated at around £1.4 billion annually). The disease is incurable and the precise causes are still unknown. Part of the Oxford Neurology Library series, this practical pocketbook summarises the latest understanding of what might cause the disease, the methods of diagnosis and assessment, and current management techniques. The book also includes chapters on variants of multiple sclerosis, on childhood-onset disease and future therapies. This pocketbook will serve as an invaluable reference for trainee neurologists, consultants needing rapid access to core facts, interested general practitioners and specialist MS nurses.
Multiple Sclerosis

Multiple Sclerosis

Sandra Amor; Hans van Noort

Oxford University Press
2012
nidottu
Multiple Sclerosis (MS) is thought to affect almost 2.5 million people worldwide. With the arrival of several new MS drugs and increased availability of information on the internet, many people are confronted by an overwhelming number of information sources about how best to manage their condition. This new book explains, in a clear and accessible way, what is currently known about MS. It provides an explanation of the disease process, symptoms, diagnosis, and how drugs and alternative approaches to disease management work. It also provides supplementary information on how lifestyle and diet changes may help. Multiple Sclerosis: The Facts addresses the most frequently asked questions about MS, and provides answers in an easy-to-read and accessible format. The book is an invaluable resource for people with MS, and their families and health care workers will also find it a go-to guide to help understand the disease more clearly. This book will also be of interest to medical students and MS researchers.
Multiple Sclerosis

Multiple Sclerosis

Gary L. Birnbaum

Oxford University Press Inc
2013
nidottu
Multiple Sclerosis (MS) is an inflammatory, often progressive, and potentially disabling disease of the central nervous system. Onset of disease is usually between the ages of 15 and 50, with the incidence nearly twice as high in women. While the cause of MS is still unknown, the predominant theory is that it is an autoimmune disease, triggered by an unknown environmental factor that results in both loss of central nervous system myelin and degeneration of axons and neurons. Although there have been a number of publications addressing different aspects of MS treatment in the neurological literature, there is a dearth of material on MS designed for internists and primary care physicians, who are often the first to see patients presenting with symptoms of MS. Therefore, this concise, clinically focused volume will serve as a valuable resource tailored to the specific needs of internists and primary care physicians. Part of the Oxford Neurology Library, this highly practical pocketbook covers current approaches and new developments in the diagnosis, treatment and management of MS, including both early and advanced stages of the disease. The book offers in-depth coverage of special populations, as well as the more unusual manifestations of MS, which are less familiar to the internal medicine audience. It will also address the role of imaging studies in the diagnosis, differential diagnosis and monitoring of the progression of MS. In addition to providing up-to-date information on pharmacological therapies for MS, the book also describes an array of non-pharmacological treatment options.
Multiple Exposures

Multiple Exposures

Catherine Caufield

University of Chicago Press
1990
pokkari
"Catherine Caufield has written an important book on an important topic: the history behind the safety standards limiting the effects of high energyradiation on human beings. . . . Provides an immense amount of informationin a very readable form." W. Alan Runciman, "Prometheus" "From fallout and radon to radioactive smoke detectors and dental X-rays, Caufield traces the proliferation of the uses of radiation in medicine, industry and the military, and in generating energy. An intelligent, non-alarmist history." "Publishers Weekly""
Multiple Paths of Midlife Development

Multiple Paths of Midlife Development

University of Chicago Press
1997
sidottu
This book analyzes the middle years of the lifespan, discussing the many different facets of adult development. This text studies the various changes experienced by middle-aged adults, explaining how these different experiences interrelate, and how a better understanding of them can foster successful midlife development. Using a diverse set of longitudinal data, the volume aims to provide a broad perspective by examining the similarities and differences in the midlife experience as a function of gender, social class, and birth cohort. The book offers advice on the enormous potential and promise which is possible amid the gains and losses of the middle years.
Multiple Sclerosis

Multiple Sclerosis

Alain L Fymat

Tellwell Talent
2023
pokkari
Multiple sclerosis (MS) is a chronic debilitating demyelinating disease of the central nervous system. It is caused by an autoimmune attack resulting in the progressive loss of the myelin sheath on neuronal axons. The resultant decrease in the speed of signal transduction leads to a loss of functionality that includes both cognitive and motor impairment depending on the location of the lesion. The progression of MS occurs due to episodes of increasing inflammation, which is proposed to be due to the release of antigens such as myelin oligodendrocyte glycoprotein, myelin basic protein, and proteolipid protein, causing an autoimmune response. This sets off a cascade of signaling molecules that result in T-cells, B-cells, and macrophages to cross the blood-brain barrier and attack myelin on neuronal axons leading to inflammation. Further release of antigens drives subsequent degeneration, causing increased inflammation. MS presents itself as a spectrum based on the degree of inflammation. A majority of patients experience early relapsing and remitting episodes of neuronal deterioration following a period of recovery. Some of these individuals may transition to a more linear progression of the disease, while about 15% of others begin with a progressive course on the onset of MS. The inflammatory response contributes to the loss of the grey matter and, as a result, current literature devotes itself to combatting the auto-inflammatory aspect of the disease. While there are several proposed causal links between the Epstein-Barr virus (EBV) and the HLA-DRB1*15:01 allele to the onset of MS - they may contribute to the degree of autoimmune attack and the resultant inflammation - they do not determine the onset of MS.
Multiple Sclerosis

Multiple Sclerosis

Alain L Fymat

Tellwell Talent
2023
sidottu
Multiple sclerosis (MS) is a chronic debilitating demyelinating disease of the central nervous system. It is caused by an autoimmune attack resulting in the progressive loss of the myelin sheath on neuronal axons. The resultant decrease in the speed of signal transduction leads to a loss of functionality that includes both cognitive and motor impairment depending on the location of the lesion. The progression of MS occurs due to episodes of increasing inflammation, which is proposed to be due to the release of antigens such as myelin oligodendrocyte glycoprotein, myelin basic protein, and proteolipid protein, causing an autoimmune response. This sets off a cascade of signaling molecules that result in T-cells, B-cells, and macrophages to cross the blood-brain barrier and attack myelin on neuronal axons leading to inflammation. Further release of antigens drives subsequent degeneration, causing increased inflammation. MS presents itself as a spectrum based on the degree of inflammation. A majority of patients experience early relapsing and remitting episodes of neuronal deterioration following a period of recovery. Some of these individuals may transition to a more linear progression of the disease, while about 15% of others begin with a progressive course on the onset of MS. The inflammatory response contributes to the loss of the grey matter and, as a result, current literature devotes itself to combatting the auto-inflammatory aspect of the disease. While there are several proposed causal links between the Epstein-Barr virus (EBV) and the HLA-DRB1*15:01 allele to the onset of MS - they may contribute to the degree of autoimmune attack and the resultant inflammation - they do not determine the onset of MS.
Multiple Normalities

Multiple Normalities

B. Misztal

Palgrave Macmillan
2015
sidottu
Multiple Normalities enhances sociological understandings of normality by illustrating it with the help of British novels. It demonstrates commonalities and differences between the meanings of normality in these two periods, exemplifying the emergence of the multiple normalities and the transformation of ways in which we give meaning to the world.
Multiple Identities

Multiple Identities

Indiana University Press
2013
sidottu
In recent years, Europeans have engaged in sharp debates about migrants and minority groups as social problems. The discussions usually neglect who these people are, how they live their lives, and how they identify themselves. Multiple Identities describes how migrants and minorities of all age groups experience their lives and manage complex, often multiple, identities, which alter with time and changing circumstances. The contributors consider minorities who have received a lot of attention, such as Turkish Germans, and some who have received little, such as Kashubians and Tartars in Poland and Chinese in Switzerland. They also examine international adoption and cross-cultural relationships and discuss some models for multicultural success.
Multiple Identities

Multiple Identities

Indiana University Press
2013
pokkari
In recent years, Europeans have engaged in sharp debates about migrants and minority groups as social problems. The discussions usually neglect who these people are, how they live their lives, and how they identify themselves. Multiple Identities describes how migrants and minorities of all age groups experience their lives and manage complex, often multiple, identities, which alter with time and changing circumstances. The contributors consider minorities who have received a lot of attention, such as Turkish Germans, and some who have received little, such as Kashubians and Tartars in Poland and Chinese in Switzerland. They also examine international adoption and cross-cultural relationships and discuss some models for multicultural success.
Multiple Chemical Sensitivities

Multiple Chemical Sensitivities

National Academies Press
1992
nidottu
Use of the term "multiple chemical sensitivity" (MCS) as a diagnostic label has generated increasing controversy during the past few decades as a phenomenon related to exposure to chemical agents sustained both in indoor and outdoor environments. This volume, prepared in conjunction with Biologic Markers in Immunotoxicology, contains the authored papers of a workshop held to develop an agenda to study the phenomenon of multiple chemical sensitivity. Authored by clinicians, immunologists, toxicologists, epidemiologists, psychiatrists, psychologists, and others involved in research or clinical activities relevant to the problem, the papers contain case evaluations and criteria for diagnosis, mechanisms potentially underlying MCS, and epidemiologic approaches to investigation. Table of Contents Front Matter Introduction Research Protocol for Clinical Evaluation Exposures and Mechanisms Epidemiology Key Concepts: Chemical Sensitization Multiple Chemical Sensitivity - What is It? Case Definitions for Multiple Chemical Sensitivity Allergy and Multiple Chemical Sensitivities (MCS) Distinguished Design of Animal Models to Probe the Mechanisms of Multiple Chemical Sensitivity Antigen Specific and Antigen Non-Specific Immunization Neuropsychiatric and Biopsychosocial Mechanisms in Multiple Chemical Sensitivity: An Olfactory-Limbic System Model Neurobehavioral and Psychosocial Aspects of Multiple Chemical Sensitivity Diagnostic Markers of Multiple Chemical Sensitivity Possible Mechanisms for Multiple Chemical Sensitivity: The Limbic System and Others Developing Clinical Research Protocols for Studying Chemical Sensitivities Immunological Mechanisms of Disease and the Multiple Chemical Sensitivity Syndrome Considerations for the Diagnosis of Chemical Sensitivity Occupational Asthma List of Contributors List of Participants
Multiple Sclerosis

Multiple Sclerosis

National Academies Press
2001
sidottu
Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered—but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families. Table of Contents Front Matter Executive Summary 1 Introduction 2 Clinical and Biological Features 3 Characteristics and Management of Major Symptoms 4 Disease Management and Measurement 5 Strategies for Future Research on Disease Mechanisms 6 Future Strategies for Therapies 7 Building and Supporting the Research Enterprise 8 Recommendations Appendix A: Committee and Staff Biographies Appendix B: List of Expert Consultants Appendix C: Workshop Agendas Appendix D: Kurtze's Expanded Disability Status Scale Appendix E: Drugs Used in the Treatment of MS Appendix F: U.S. Social Security Administration's Criteria for Qualifying as Disabled from MS Appendix G: Treatments That Have Been Claimed to Be of Benefit in MS Index
Multiple Origins, Uncertain Destinies
Given current demographic trends, nearly one in five U.S. residents will be of Hispanic origin by 2025. This major demographic shift and its implications for both the United States and the growing Hispanic population make Multiple Origins, Uncertain Destinies a most timely book. This report from the National Research Council describes how Hispanics are transforming the country as they disperse geographically. It considers their roles in schools, in the labor market, in the health care system, and in U.S. politics. The book looks carefully at the diverse populations encompassed by the term "Hispanic," representing immigrants and their children and grandchildren from nearly two dozen Spanish-speaking countries. It describes the trajectory of the younger generations and established residents, and it projects long-term trends in population aging, social disparities, and social mobility that have shaped and will shape the Hispanic experience.Table of ContentsFront MatterExecutive Summary1 Introduction2 Multiple Origins, Hispanic Portrait3 Defining Hispanicity: E Pluribus Unum or E Pluribus Plures?4 The Challenges of Integration5 Realms of Integration: Family, Education, Work, and Health6 Uncertain DestiniesReferencesAppendix A MethodsAppendix B Biographical Sketches of Panel Members and StaffAppendix C Contents `Hispanics and the Future of America`Index