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428 tulosta hakusanalla "Tissue Engineering"

Cardiac Tissue Engineering

Cardiac Tissue Engineering

Smadar Cohen; Emil Ruvinov; Yulia Sapir

Springer International Publishing AG
2011
nidottu
Cardiac tissue engineering aims at repairing damaged heart muscle and producing human cardiac tissues for application in drug toxicity studies. This book offers a comprehensive overview of the cardiac tissue engineering strategies, including presenting and discussing the various concepts in use, research directions and applications. Essential basic information on the major components in cardiac tissue engineering, namely cell sources and biomaterials, is firstly presented to the readers, followed by a detailed description of their implementation in different strategies, broadly divided to cellular and acellular ones. In cellular approaches, the biomaterials are used to increase cell retention after implantation or as scaffolds when bioengineering the cardiac patch, in vitro. In acellular approaches, the biomaterials are used as ECM replacement for damaged cardiac ECM after MI, or, in combination with growth factors, the biomaterials assume an additional function as a depot for prolonged factor activity for the effective recruitment of repairing cells. The book also presents technological innovations aimed to improve the quality of the cardiac patches, such as bioreactor applications, stimulation patterns and prevascularization. This book could be of interest not only from an educational perspective (i.e. for graduate students), but also for researchers and medical professionals, to offer them fresh views on novel and powerful treatment strategies. We hope that the reader will find a broad spectrum of ideas and possibilities described in this book both interesting and convincing. Table of Contents: Introduction / The Heart: Structure, Cardiovascular Diseases, and Regeneration / Cell Sources for Cardiac Tissue Engineering / Biomaterials: Polymers, Scaffolds, and Basic Design Criteria / Biomaterials as Vehicles for Stem Cell Delivery and Retention in the Infarct / Bioengineering of Cardiac Patches, In Vitro / Perfusion Bioreactors and Stimulation Patterns in Cardiac Tissue Engineering / Vascularization of Cardiac Patches / Acellular Biomaterials for Cardiac Repair / Biomaterial-based Controlled Delivery of Bioactive Molecules for Myocardial Regeneration
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Osteochondral Tissue Engineering

Osteochondral Tissue Engineering

Springer International Publishing AG
2018
sidottu
This book reviews the most recent developments in the field of osteochondral tissue engineering (OCTE) and presents challenges and strategies being developed that face not only bone and cartilage regeneration, but also establish osteochondral interface formation in order to translate it into a clinical setting. Topics include nanotechnology approaches and biomaterials advances in osteochondral engineering, advanced processing methodology, as well as scaffolding and surface engineering strategies in OCTE. Hydrogel systems for osteochondral applications are also detailed thoroughly. Osteochondral Tissue Engineering: Nanotechnology, Scaffolding-Related Developments and Translation is an ideal book for biomedical engineering students and a wide range of established researchers and professionals working in the orthopedic field.
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Osteochondral Tissue Engineering

Osteochondral Tissue Engineering

Springer International Publishing AG
2018
sidottu
This book covers the most recent developments in the field of osteochondral tissue engineering (OCTE) and covers in detail the concepts and current challenges for bone and cartilage repair and regeneration. Specific topics include viscosupplementation, biologicals, tissue engineering approaches, in vitro and in vivo models, and technological advances with stem cells, bioreactors, and microfluidics. Osteochondral Tissue Engineering: Challenges, Current Strategies, and Technological Advances presents challenges and strategies in the field of osteochondral regeneration and serves as a core reference for biomedical engineering students and a wide range of established researchers and professionals working in orthopedics.
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Myocardial Tissue Engineering

Myocardial Tissue Engineering

Springer-Verlag Berlin and Heidelberg GmbH Co. K
2011
sidottu
Myocardial tissue engineering (MTE), a concept that intends to prolong patients’ life after cardiac damage by supporting or restoring heart function, is continuously improving. Common MTE strategies include an engineered ‘vehicle’, which may be a porous scaffold or a dense substrate or patch, made of either natural or synthetic polymeric materials. The function of the substrate is to aid transportation of cells into the diseased region of the heart and support their integration. This book, which contains chapters written by leading experts in MTE, gives a complete analysis of the area and presents the latest advances in the field. The chapters cover all relevant aspects of MTE strategies, including cell sources, specific TE techniques and biomaterials used. Many different cell types have been suggested for cell therapy in the framework of MTE, including autologous bone marrow-derived or cardiac progenitors, as well as embryonic or induced pluripotent stem cells, each having their particular advantages and disadvantages. The book covers a complete range of biomaterials, examining different aspects of their application in MTE, such as biocompatibility with cardiac cells, mechanical capability and compatibility with the mechanical properties of the native myocardium as well as degradation behaviour in vivo and in vitro. Although a great deal of research is being carried out in the field, this book also addresses many questions that still remain unanswered and highlights those areas in which further research efforts are required. The book will also give an insight into clinical trials and possible novel cell sources for cell therapy in MTE.
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Myocardial Tissue Engineering

Myocardial Tissue Engineering

Springer-Verlag Berlin and Heidelberg GmbH Co. K
2013
nidottu
Myocardial tissue engineering (MTE), a concept that intends to prolong patients’ life after cardiac damage by supporting or restoring heart function, is continuously improving. Common MTE strategies include an engineered ‘vehicle’, which may be a porous scaffold or a dense substrate or patch, made of either natural or synthetic polymeric materials. The function of the substrate is to aid transportation of cells into the diseased region of the heart and support their integration. This book, which contains chapters written by leading experts in MTE, gives a complete analysis of the area and presents the latest advances in the field. The chapters cover all relevant aspects of MTE strategies, including cell sources, specific TE techniques and biomaterials used. Many different cell types have been suggested for cell therapy in the framework of MTE, including autologous bone marrow-derived or cardiac progenitors, as well as embryonic or induced pluripotent stem cells, each having their particular advantages and disadvantages. The book covers a complete range of biomaterials, examining different aspects of their application in MTE, such as biocompatibility with cardiac cells, mechanical capability and compatibility with the mechanical properties of the native myocardium as well as degradation behaviour in vivo and in vitro. Although a great deal of research is being carried out in the field, this book also addresses many questions that still remain unanswered and highlights those areas in which further research efforts are required. The book will also give an insight into clinical trials and possible novel cell sources for cell therapy in MTE.
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Oral Tissue Engineering

Oral Tissue Engineering

Mandeep Singh; Nishant Singh; Sanjit Singh

Lap Lambert Academic Publishing
2024
pokkari
Oral Tissue Engineering: Revolutionizing Dental Medicine" is a groundbreaking book that delves into the innovative field of oral tissue engineering. This comprehensive guide illuminates the latest research and advancements in the regeneration and repair of oral tissues, offering a new horizon in dental medicine. The book covers a range of topics, from the fundamental science behind cell and tissue growth to cutting-edge techniques in stem cell therapy, scaffold design, and biomaterials. It highlights the potential for regenerating dental tissues, including enamel, dentin, pulp, and periodontal structures, offering hope for patients suffering from dental diseases and injuries.The authors, renowned experts in dental science and bioengineering, provide a detailed exploration of the challenges and opportunities in this rapidly evolving field. They discuss the ethical, regulatory, and practical aspects of oral tissue engineering, making the book an invaluable resource for dental professionals, researchers, and students alike.
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Applied Tissue Engineering

Applied Tissue Engineering

In Tech
2011
sidottu
Tissue engineering, which aims at regenerating new tissues, as well as substituting lost organs by making use of autogenic or allogenic cells in combination with biomaterials, is an emerging biomedical engineering field. There are several driving forces that presently make tissue engineering very challenging and important: 1) the limitations in biological functions of current artificial tissues and organs made from man-made materials alone, 2) the shortage of donor tissue and organs for organs transplantation, 3) recent remarkable advances in regeneration mechanisms made by molecular biologists, as well as 4) achievements in modern biotechnology for large-scale tissue culture and growth factor production. This book was edited by collecting all the achievement performed in the laboratory of oral and maxillofacial surgery and it brings together the specific experiences of the scientific community in these experiences of our scientific community in this field as well as the clinical experiences of the most renowned experts in the fields from all over Nagoya University. The editors are especially proud of bringing together the leading biologists and material scientists together with dentist, plastic surgeons, cardiovascular surgery and doctors of all specialties from all department of the medical school of Nagoya University. Taken together, this unique collection of world-wide expert achievement and experiences represents the current spectrum of possibilities in tissue engineered substitution.
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Mimicked Tissue Engineering Scaffolds for Maxillofacial and Articular Cartilage Surgery

Mimicked Tissue Engineering Scaffolds for Maxillofacial and Articular Cartilage Surgery

Jirut Meesane

SPRINGER VERLAG, SINGAPORE
2022
sidottu
This book outlines the latest research on the design and fabrication of the biomaterials used in mimicked scaffolds for tissue engineering for maxillofacial and orthopedic applications. The book is written based on integration and optimized concepts of 3 main parts 1) principle of tissue engineering; 2) mimicking of structure and function of scaffolds which is similar to extracellular matrix (ECM); and 3) mimicked scaffolds for tissue engineering in maxillofacial and orthopedic surgery. The content of this book which is interdisciplinary in nature caters to medical product designers, materials scientists and engineers, biologists, and surgeons who have interest in the field of bone tissue engineering.
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Mimicked Tissue Engineering Scaffolds for Maxillofacial and Articular Cartilage Surgery

Mimicked Tissue Engineering Scaffolds for Maxillofacial and Articular Cartilage Surgery

Jirut Meesane

SPRINGER VERLAG, SINGAPORE
2023
nidottu
This book outlines the latest research on the design and fabrication of the biomaterials used in mimicked scaffolds for tissue engineering for maxillofacial and orthopedic applications. The book is written based on integration and optimized concepts of 3 main parts 1) principle of tissue engineering; 2) mimicking of structure and function of scaffolds which is similar to extracellular matrix (ECM); and 3) mimicked scaffolds for tissue engineering in maxillofacial and orthopedic surgery. The content of this book which is interdisciplinary in nature caters to medical product designers, materials scientists and engineers, biologists, and surgeons who have interest in the field of bone tissue engineering.
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Myocardial Tissue Engineering

Myocardial Tissue Engineering

Pan Stanford Publishing Pte Ltd
2015
sidottu
Regenerative therapy has rapidly developed as one of the most promising treatments for patients suffering from severe heart failure. Autologous bone marrow-derived cells and cardiac stem cells have been clinically applied for cell injection therapy for heart failure. As a next-generation therapy, tissue-engineered myocardial-patch transplantation has also been started clinically. As further advanced therapy, several researchers have started to fabricate three-dimensional beating myocardial tissues. One of the main problems in myocardial tissue engineering is neovascularization within the tissues during scale-up. Several innovative technologies have been developed to overcome the vascularization problem.This book broadly summarizes myocardial tissue engineering and regenerative medicine, which consists of myocardial cell sources, cell therapy for damaged hearts, and tissue engineering technologies for fabricating beating hearts. With respect to myocardial cell source, it focuses on cardiac cells differentiated from embryonic stem and induced pluripotent stem cells. It describes the remarkable results obtained in the past and the present to control neovascularization and presents the future challenges in myocardial tissue engineering research.
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Skin Tissue Engineering and Regenerative Medicine

Skin Tissue Engineering and Regenerative Medicine

FOSTER ACADEMICS
2025
sidottu
Skin tissue engineering involves creating lab-grown skin for medical applications. It combines cells, biomaterials, and biochemical factors to develop skin substitutes for treating burns, wounds, and skin disorders. This field aims to enhance healing and regeneration, providing functional and aesthetic restoration of damaged skin. Skin tissue engineering and regenerative medicine offer promising solutions for repairing damaged or diseased skin. By combining principles from biology, engineering, and materials science, researchers aim to develop biomimetic skin substitutes that can effectively regenerate skin function and structure. These substitutes often utilize scaffolds seeded with cells to mimic the native extracellular matrix and promote tissue regeneration. Additionally, advancements in stem cell therapy and gene editing techniques further enhance the potential for personalized treatments tailored to individual patients. From theories to research to practical applications, case studies related to all contemporary topics of relevance to this field have been included in this book. Most of the topics introduced in this book cover new techniques and the applications of skin tissue engineering. It will serve as a valuable source of reference for graduate and post graduate students.
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Contemporary Tissue Engineering and Regenerative Medicine

Contemporary Tissue Engineering and Regenerative Medicine

Elena García-Gareta; José Manuel García-Aznar

Springer Nature Switzerland AG
2026
sidottu
This book offers a current overview of Tissue Engineering and Regenerative Medicine (TERM), highlighting key technological and methodological advances. It introduces core TERM concepts and strategies for tissue and organ regeneration, along with the bioengineering of tissue models based on modern principles.
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Functional 3D Tissue Engineering Scaffolds

Functional 3D Tissue Engineering Scaffolds

Woodhead Publishing Ltd
2017
sidottu
In order to grow replacement tissues, 3D scaffolds are widely used as a template for tissue engineering and regeneration. These scaffolds, which are typically ‘seeded’ with cells, support the growth of new tissues. However, in order to achieve successful tissue growth, the scaffold must meet specific requirements and are often ‘functionalized’ to accentuate particular properties. Functional 3D tissue engineering scaffolds: materials, technologies, and applications, is a comprehensive review of functional 3D scaffolds, providing information on the fundamentals, technologies, and applications. Part 1 focuses on the fundamentals of 3D tissue scaffolds, examining information on materials, properties, and trends. Part 2 discusses a wide range of conventional technologies for engineering functional 3D scaffolds, leading the way to a discussion on CAD and advanced technologies for functional 3D scaffold engineering. Chapters in part 3 study methods for functionalizing scaffolds to support a variety of in vivo functions whilst the final set of chapters provides an important review of the most significant applications of functional 3D scaffolds within tissue engineering. This book is a valuable resource for biomaterial scientists and biomedical engineers in academia and industry, with interests in tissue engineering and regenerative medicine.
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