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1000 tulosta hakusanalla V J Sims

An Introduction to Chemoinformatics

An Introduction to Chemoinformatics

Andrew R. Leach; V.J. Gillet

Springer-Verlag New York Inc.
2003
sidottu
Chemoinformatics draws upon techniques from many disciplines including computer science, mathematics, computational chemistry and data visualisation to tackle these problems. This, the first text written specifically for this field, aims to provide an introduction to the major techniques of chemoinformatics. The first part of the book deals with the representation of 2D and 3D molecular structures, the calculation of molecular descriptors and the construction of mathematical models. The second part describes other important topics including molecular similarity and diversity, the analysis of large data sets, virtual screening, and library design. Simple illustrative examples are used throughout to illustrate key concepts, supplemented with case studies from the literature. The book is aimed at graduate students, final-year undergraduates, and professional scientists. No prior knowledge is assumed other than a familiarity with chemistry and some basic mathematical concepts.
An Introduction to Chemoinformatics

An Introduction to Chemoinformatics

Andrew R. Leach; V.J. Gillet

Springer-Verlag New York Inc.
2007
nidottu
Chemoinformatics draws upon techniques from many disciplines including computer science, mathematics, computational chemistry and data visualisation to tackle these problems. This, the first text written specifically for this field, aims to provide an introduction to the major techniques of chemoinformatics. The first part of the book deals with the representation of 2D and 3D molecular structures, the calculation of molecular descriptors and the construction of mathematical models. The second part describes other important topics including molecular similarity and diversity, the analysis of large data sets, virtual screening, and library design. Simple illustrative examples are used throughout to illustrate key concepts, supplemented with case studies from the literature. The book is aimed at graduate students, final-year undergraduates, and professional scientists. No prior knowledge is assumed other than a familiarity with chemistry and some basic mathematical concepts.
Plant Analysis Manual

Plant Analysis Manual

I. Walinga; J.J. van der Lee; V.J.G. Houba; W. van Vark; I. Novozamsky

Springer
2012
nidottu
In the field of plant analysis there is a confusing variety of methods and procedures, both for digestions and determinations. In many cases the digestion and the subsequent determination are interrelated. For example, a separate digestion is needed for trace elements in order to obtain determinable concentrations. The authors have chosen a design in which the digestion/extraction procedure is described in one chapter together with all determination procedures that may be carried out on that particular digest/extract. All the necessary information (such as standardizations) appears in appendices. As a consequence, several determination procedures are described two or three times, however, each based on a particular digestion or extraction method. Two types of determination procedure are described: manual and automated. Manual procedures are mainly used in research laboratories, whereas automated procedures are more frequently applied in routine laboratories. Both types of determinations can be used freely, provided that appropriate equipment is available. The determination procedures are only for inorganic components, usually elements. Besides, most procedures are designed to give a total content value of the element under consideration, regardless of the chemical structure in which it occurs in the plant. The Plant Analysis Manual is intended for the practicing (agricultural) chemist.
Soil Science for Competitive Exams

Soil Science for Competitive Exams

R. R. Sisodiya; R R Sisodiya; H. P. Dholariya; H P Dholariya; V. J. Zinzala; V J Zinzala

Lap Lambert Academic Publishing
2026
nidottu
These books are a key resource for students preparing for national and state-level exams such as the Indian Council of Agricultural Research (ICAR) Junior Research Fellowship (JRF), Senior Research Fellow (SRF), Agricultural Research Services (ARS), National Eligibility Test (NET), and various State Agricultural Universities (SAU) entrance examinations for postgraduate and PhD courses.By providing a wide range of small questions answers like multiple-choice questions (MCQs), these books help students solidify their grasp and understanding of core soil science concepts, including soil physics, chemistry, microbiology, and fertility.
V(D)J Recombination

V(D)J Recombination

Springer-Verlag New York Inc.
2009
sidottu
v(D)J recombination: for the community of immunologists and developmental biologists, the molecular route by which B and T lymphocytes acquire their unique function of affording adaptive immunity. Yet, for many-from experienced scientists to trainees-it represents a (rather too) sophisticated process whose true insight is excessively demanding. However, when not simplyconsidered as a private ground for a few aficionados, it can be seen as a way of understanding how maturelympho­ cytes carry on their basic functions. For the group of aficionados-which includes this editor-it is an elegant paradigm featuring many fascinating evolutionary achievements of which the biological world alone has the secret. These include a subtle biochemical principle most likelyhijacked some 470 million years ago from an ancestral gene invader and since then cleverly adapted by jawed vertebrates to precisely cleave and rearrange their antigen receptor (Ig andTCR)loci. This invader would itself have assigned the services of the nonhomologous end joining (NHEJ) DNArepair machinery as well as various DNApolymerases or transferases to work in concert with developmental clues in lymphoid cell lineages to generate an immune repertoire and efficient host surveillance while avoiding autoimmunity. Recently, important new refinements in these systems have emerged, continuing to challenge ourknowledge andbeliefs. These arejust thetopics covered by the senior authors-all established leaders in this field-and their colleagues, whilst writing the various chapters in V(D)J Recombination.
V(D)J Recombination

V(D)J Recombination

Springer-Verlag New York Inc.
2014
nidottu
v(D)J recombination: for the community of immunologists and developmental biologists, the molecular route by which B and T lymphocytes acquire their unique function of affording adaptive immunity. Yet, for many-from experienced scientists to trainees-it represents a (rather too) sophisticated process whose true insight is excessively demanding. However, when not simplyconsidered as a private ground for a few aficionados, it can be seen as a way of understanding how maturelympho­ cytes carry on their basic functions. For the group of aficionados-which includes this editor-it is an elegant paradigm featuring many fascinating evolutionary achievements of which the biological world alone has the secret. These include a subtle biochemical principle most likelyhijacked some 470 million years ago from an ancestral gene invader and since then cleverly adapted by jawed vertebrates to precisely cleave and rearrange their antigen receptor (Ig andTCR)loci. This invader would itself have assigned the services of the nonhomologous end joining (NHEJ) DNArepair machinery as well as various DNApolymerases or transferases to work in concert with developmental clues in lymphoid cell lineages to generate an immune repertoire and efficient host surveillance while avoiding autoimmunity. Recently, important new refinements in these systems have emerged, continuing to challenge ourknowledge andbeliefs. These arejust thetopics covered by the senior authors-all established leaders in this field-and their colleagues, whilst writing the various chapters in V(D)J Recombination.
S.J.V.Chelvanayakam and the Crisis of Sri Lankan Tamil Nationalism, 1947-77
S.J. Chelvanayakam was one of the most prominent leaders of the Ceylon Tamils before and after the end of colonial rule, and in the early days of their struggle for political and economic equality. The author, who knew Chelvanayakam intimately, analyzes in this work his career and his symbiotic relationship with the Ceylon Tamils, which led eventually to the emergence and reinforcing of a defensive Ceylon Tamil nationalism. The work is based on personal papers, interviews with leading protagonists, parliamentary records and the English and Tamil press. It is also conceived by the author as a model for the study of ethno-nationalism, the politics of Gandhian protest and of crisis leadership in a multi-ethnic Third World state.
The Complete Essays of J. V. Cunningham

The Complete Essays of J. V. Cunningham

J V Cunningham

Wiseblood Books
2024
sidottu
A "renegade Irish Catholic from the plains of Montana, upper lower class, a onetime scholar in Latin and in the English Renaissance," J. V. Cunningham is known for formal verse that is clear and concise. A master of the epigram, Cunningham also wrote longer poems in what is often called the Plain Style. Though Cunningham's poetic output was small, he also left us a standout, wide-ranging body of essays. As James Matthew Wilson notes in his introduction, " Cunningham's] work in verse and prose were two ways of speaking within a single way of life; they were complementary means toward a single end." In these essays, Cunningham makes intelligible the "Tradition and Poetic Structure" of our literary inheritance, taking us from the ancient poet "Statius on Sleep" to the "Woe or Wonder" of Shakespeare's pathos, "Sorting Out," along the way, the legend of Emily Dickinson. In "Logic and Lyric," he presents his soberly learned, but renegade argument against the "incautious romantic's" absolute separation of poetry and philosophy, and with winsome wit he prompts us to consider: "May a lyric be solely or predominantly the exposition of a syllogism? and may the propositions of the lyric, one by one, be of the sort to be found in a logical syllogism?" The only book that contains the complete collection of Cunningham's known essays, this Wiseblood edition includes everything contained in Swallow Press's The Collected Essays of J. V. Cunningham, as well as six additional prose pieces, an expansive introduction from James Matthew Wilson, and an interview with Timothy Steele. "To follow him on the path, however tentatively and with however many reservations, was to break bread with the modestly great; it was to learn the meaning and practice of poetry in an atmosphere of seriousness and near silence; it was to set out on pilgrimage in search of a more classical, more disciplined, more compelling and intelligent way of living, knowing, and writing in the world." -from the Introduction by James Matthew Wilson
J.V. Snellman

J.V. Snellman

Raija Majamaa; Leeni Tiirakari

SUOMALAISEN KIRJALLISUUDEN SEURA
2006
nidottu
Pertti Karkama käsittelee Snellmanin kirjallisuuspolitiikkaa, joka liittyi elimellisesti hänen yhteiskunnalliseen ja sivistykselliseen toimintaansa. Snellman antoi kirjallisuudelle suuren merkityksen kansallishengen herättämisessä ja kansallisvaltion syntyprosessissa. Tutkimuksessa Snellman esitellään hengen ja toiminnan miehenä, joka piti tärkeimpänä tehtävänään välittää Suomeen Euroopan kulttuurinen ja kirjallinen traditio. Tutkimuksessa seuraillaan Snellmanin maailmankatsomuksen, kirjallisuuskäsityksen ja kirjallisuuspoliittisen toiminnan kehitystä 1830-luvulta 1880-luvulle. Etenkin eurooppalaisten vaikutteiden erittely täydentää ja syventää Snellmanin usein liian nationalistiseksi piirrettyä kuvaa.
Notice Biographique Sur J.-V.-F. Lamouroux, Professeur d'Histoire Naturelle À l'Académie Royale
Notice biographique sur J.-V.-F. Lamouroux, professeur d'histoire naturelle a l'Academie royale de Caen... par J.-P. Lamouroux, ...Date de l'edition originale: 1829Ce livre est la reproduction fidele d'une oeuvre publiee avant 1920 et fait partie d'une collection de livres reimprimes a la demande editee par Hachette Livre, dans le cadre d'un partenariat avec la Bibliotheque nationale de France, offrant l'opportunite d'acceder a des ouvrages anciens et souvent rares issus des fonds patrimoniaux de la BnF.Les oeuvres faisant partie de cette collection ont ete numerisees par la BnF et sont presentes sur Gallica, sa bibliotheque numerique.En entreprenant de redonner vie a ces ouvrages au travers d'une collection de livres reimprimes a la demande, nous leur donnons la possibilite de rencontrer un public elargi et participons a la transmission de connaissances et de savoirs parfois difficilement accessibles.Nous avons cherche a concilier la reproduction fidele d'un livre ancien a partir de sa version numerisee avec le souci d'un confort de lecture optimal. Nous esperons que les ouvrages de cette nouvelle collection vous apporteront entiere satisfaction.Pour plus d'informations, rendez-vous sur www.hachettebnf.fr
The Development by J.V. Stalin of the Marxist-Leninist Theory of the National Question
This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface.We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.