Kirjahaku

The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields.

Key features:High quality full color photographs and descriptive texts on the location and removal of the organs from the mouseInstructive methods and clear visuals for trimming and orienting the organs for paraffin histology to obtain the best possible sections for analysisFull color photomicrographs of the resulting section for each organ stained with hematoxylin and eosin demonstrating important features and landmarks for the histologist to ensure the optimal area for analysis is achievedAll in one, easy to use guide organized by individual organs of the laboratory mouse Spiralbound for easy reference in the lab This "one-stop" guide offers an essential resource for any academic, research or development operation where mouse necropsy and/or histology are performed. Connecting the reader ‘from the mouse to the microscope’, it provides a detailed guide for locating, trimming, orientating and embedding of the most frequently investigated tissues collected in the laboratory mouse. It shows where the organs reside in the mouse, how to trim and embed them as well as the resulting optimal sections. This guide brings together the wealth of scattered information into one high-quality text, the emphasis is on providing knowledge that will help histologists and scientists get better results in any downstream assays where ideal sections are needed.

Key features:High quality full color photographs and descriptive texts on the location and removal of the organs from the mouseInstructive methods and clear visuals for trimming and orienting the organs for paraffin histology to obtain the best possible sections for analysisFull color photomicrographs of the resulting section for each organ stained with hematoxylin and eosin demonstrating important features and landmarks for the histologist to ensure the optimal area for analysis is achievedAll in one, easy to use guide organized by individual organs of the laboratory mouse Spiralbound for easy reference in the lab This "one-stop" guide offers an essential resource for any academic, research or development operation where mouse necropsy and/or histology are performed. Connecting the reader ‘from the mouse to the microscope’, it provides a detailed guide for locating, trimming, orientating and embedding of the most frequently investigated tissues collected in the laboratory mouse. It shows where the organs reside in the mouse, how to trim and embed them as well as the resulting optimal sections. This guide brings together the wealth of scattered information into one high-quality text, the emphasis is on providing knowledge that will help histologists and scientists get better results in any downstream assays where ideal sections are needed.

With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. Revised to reflect advances since the second edition, The Laboratory Mouse continues to be the most accessible reference on the biology and care of the mouse in research settings. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers on the humane care and use of the mouse. The new edition adds information on novel technologies such as CRISPR-Cas and on housing systems and management practices; it covers new concepts such as pain assessment by facial expression and the importance of nest-building as an assessment tool of well-being. There are now expanded sections on anesthesia and analgesia, and on behavior and enrichment.An ideal quick reference for investigators, technicians, and animal caretakers charged with the care and/or use of mice in a research setting, this book will be particularly valuable to those new to working with mice who need to start research programs using these animals.

With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. Revised to reflect advances since the second edition, The Laboratory Mouse continues to be the most accessible reference on the biology and care of the mouse in research settings. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers on the humane care and use of the mouse. The new edition adds information on novel technologies such as CRISPR-Cas and on housing systems and management practices; it covers new concepts such as pain assessment by facial expression and the importance of nest-building as an assessment tool of well-being. There are now expanded sections on anesthesia and analgesia, and on behavior and enrichment.An ideal quick reference for investigators, technicians, and animal caretakers charged with the care and/or use of mice in a research setting, this book will be particularly valuable to those new to working with mice who need to start research programs using these animals.

This book has been considered by academicians and scholars of great significance and value to literature. This forms a part of the knowledge base for future generations. So that the book is never forgotten we have represented this book in a print format as the same form as it was originally first published. Hence any marks or annotations seen are left intentionally to preserve its true nature.

This book has been considered by academicians and scholars of great significance and value to literature. This forms a part of the knowledge base for future generations. So that the book is never forgotten we have represented this book in a print format as the same form as it was originally first published. Hence any marks or annotations seen are left intentionally to preserve its true nature.

This book constitutes a unique source of hard-copy information on mouse variants and is an essential work of reference for biologists who use mouse genetic strains and variants in their research. The third edition reflects the great expansion of knowledge in the field in recent years, and includes new chapters and data. As in earlier editions, the main chapter provides a catalogue of all known mouse genes. Genetic maps are supported by a large table of data on recombination fractions.