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639 tulosta hakusanalla Alok Jain

Transdermal Patch of Lamivudine and Stavudine-Loaded Ethosomes

Transdermal Patch of Lamivudine and Stavudine-Loaded Ethosomes

Shailesh Gupta; Ravikant Gupta; Alok Pail Jain

LAP Lambert Academic Publishing
2020
pokkari
TDDS are the ideal delivery system for drug that undergo hepatic first pass metabolism. Lamivudine and Stavudune drug was successfully designed and developed by trial and error method. Formulations were prepared by employing combination of HPMCK15M, PVPK30, and EC in various ratios. From the evaluation results it was conclude that TF5 show highest release at 12 hrs. with suitable polymer ratio and penetration enhancer and it was observed that Higuchi kinetics model most suitable kinetic model for drug release from all patches.
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Hidrogéis fabricados com apigenina

Hidrogéis fabricados com apigenina

Sushil Kumar Kashaw; Rajesh Shukla; Alok Pal Jain

Edicoes Nosso Conhecimento
2024
pokkari
A ferida uma rutura da integridade epitelial da pele que resulta de uma agress o ou de um traumatismo e que pode ser seguida de uma perturba o da estrutura e do papel do tecido normal subjacente. Foi afirmado que a hiperglicemia tem um efeito t xico na cicatriza o de feridas atrav s da forma o de produtos finais de glica o avan ada que induzem a cria o de mol culas inflamat rias (TNF-, IL-1) e dificultam a s ntese de colag nio. Com o n vel elevado de glicose tamb m se alteram a morfologia celular, reduz-se a prolifera o, o tecido de granula o fica com falta de colag nio e h uma diferencia o anormal dos queratin citos. Os hidrog is (HGs) s o redes de pol meros tridimensionais que incham com grandes quantidades de um solvente. Os hidrog is t m uma textura flex vel, borrachosa e macia, assemelhando-se a tecidos humanos com conten o influente como aplica o em feridas. Os hidrog is s o particularmente vantajosos porque podem evitar a perda de gua e a infe o secund ria, absorver os fluidos da ferida e proporcionar uma troca gasosa adequada. Devido estrutura amorfa do hidrogel de goma gelana-quitosano (GGCH).
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Idrogeli fabbricati con apigenina

Idrogeli fabbricati con apigenina

Sushil Kumar Kashaw; Rajesh Shukla; Alok Pal Jain

Edizioni Sapienza
2024
pokkari
La ferita una rottura dell'integrit epiteliale della pelle che deriva da un'aggressione o da un trauma e che pu essere seguita da un'alterazione della struttura e del ruolo del tessuto normale sottostante. stato affermato che l'iperglicemia ha un effetto tossico sulla guarigione delle ferite attraverso la formazione di prodotti finali della glicazione avanzata che inducono la creazione di molecole infiammatorie (TNF-, IL-1) e ostacolano la sintesi del collagene. Con l'alto livello di glucosio si modificano anche la morfologia cellulare, si riduce la proliferazione, il tessuto di granulazione privo di collagene e la differenziazione dei cheratinociti anormale. Gli idrogel (HG) sono reti di polimeri tridimensionali che si gonfiano grazie a enormi quantit di solvente. Gli idrogel hanno una consistenza flessibile, gommosa e morbida, simile a quella dei tessuti umani, con un'applicazione influente sulle ferite. Gli idrogel sono particolarmente vantaggiosi perch possono prevenire la perdita di acqua e le infezioni secondarie, assorbire i fluidi della ferita e fornire un adeguato scambio gassoso. Grazie alla struttura amorfa della gomma gellano-chitosano (GGCH), gli idrogel (HG) possono assorbire acqua fino al 99% del proprio peso.
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Hydrogels fabriqués à base d'apigénine

Hydrogels fabriqués à base d'apigénine

Sushil Kumar Kashaw; Rajesh Shukla; Alok Pal Jain

Editions Notre Savoir
2024
pokkari
La plaie est une rupture de l'int grit pith liale de la peau qui r sulte d'une agression ou d'un traumatisme et qui peut tre suivie d'une perturbation de la structure et du r le du tissu normal sous-jacent. Il a t d montr que l'hyperglyc mie a un effet toxique sur la cicatrisation des plaies par la formation de produits finaux de glycation avanc e qui favorisent la cr ation de mol cules inflammatoires (TNF-, IL-1) et entravent la synth se du collag ne. Le taux lev de glucose entra ne galement des modifications de la morphologie cellulaire, une r duction de la prolif ration, un manque de collag ne dans le tissu de granulation et une diff renciation anormale des k ratinocytes. Les hydrogels (HG) sont des r seaux de polym res tridimensionnels gonfl s par d' normes quantit s de solvant. Les hydrogels ont une texture souple, caoutchouteuse et molle qui ressemble celle des tissus humains, ce qui leur conf re une grande influence dans l'application sur les plaies. Les hydrogels sont particuli rement avantageux car ils peuvent emp cher la perte d'eau et l'infection secondaire, absorber les fluides de la plaie et fournir un change gazeux ad quat. En raison de la structure amorphe de la gomme gellane et du chitosane (GGCH), les hydrogels peuvent absorber de l'eau jusqu' 99 % de leur propre poids.
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Mit Apigenin hergestellte Hydrogele

Mit Apigenin hergestellte Hydrogele

Sushil Kumar Kashaw; Rajesh Shukla; Alok Pal Jain

Verlag Unser Wissen
2024
pokkari
Eine Wunde ist eine Verletzung der epithelialen Integrit t der Haut, die auf eine Aggression oder ein Trauma zur ckzuf hren ist und durch eine St rung der Struktur und der Funktion des darunter liegenden normalen Gewebes hervorgerufen werden kann. Es wurde festgestellt, dass Hyperglyk mie eine toxische Wirkung auf die Wundheilung durch die Bildung von fortgeschrittenen Glykierungsendprodukten hat, die die Bildung von Entz ndungsmolek len (TNF-, IL-1) f rdern und die Kollagensynthese behindern. Mit dem hohen Glukosespiegel ver ndern sich auch die Zellmorphologie, die Proliferation nimmt ab, dem Granulationsgewebe mangelt es an Kollagen und die Differenzierung der Keratinozyten ist gest rt. Hydrogele (HGs) sind Netzwerke aus dreidimensionalen Polymeren, die durch gro e Mengen eines L sungsmittels aufgequollen sind. Die HGs haben eine flexible, gummiartige und weiche Textur, die dem menschlichen Gewebe hnelt und sich hervorragend f r die Wundbehandlung eignet. Hydrogele sind besonders vorteilhaft, weil sie Wasserverluste und Sekund rinfektionen verhindern, Wundfl ssigkeiten absorbieren und f r einen ausreichenden Gasaustausch sorgen k nnen. Aufgrund der amorphen Struktur von Gellan-Gummi-Chitosan (GGCH) k nnen Hydrogele (HGs) bis zu 99 % ihres Eigengewichts an Wasser aufnehmen.
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Ensemble Learning for AI Developers

Ensemble Learning for AI Developers

Alok Kumar; Mayank Jain

APress
2020
nidottu
Use ensemble learning techniques and models to improve your machine learning results.Ensemble Learning for AI Developers starts you at the beginning with an historical overview and explains key ensemble techniques and why they are needed. You then will learn how to change training data using bagging, bootstrap aggregating, random forest models, and cross-validation methods. Authors Kumar and Jain provide best practices to guide you in combining models and using tools to boost performance of your machine learning projects. They teach you how to effectively implement ensemble concepts such as stacking and boosting and to utilize popular libraries such as Keras, Scikit Learn, TensorFlow, PyTorch, and Microsoft LightGBM. Tips are presented to apply ensemble learning in different data science problems, including time series data, imaging data, and NLP. Recent advances in ensemble learning are discussed. Sample code is provided in the form of scripts and the IPython notebook.What You Will LearnUnderstand the techniques and methods utilized in ensemble learningUse bagging, stacking, and boosting to improve performance of your machine learning projects by combining models to decrease variance, improve predictions, and reduce biasEnhance your machine learning architecture with ensemble learningWho This Book Is ForData scientists and machine learning engineers keen on exploring ensemble learning
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Nanotechnology and its role in Periodontics

Nanotechnology and its role in Periodontics

Akanksha Jain; Jyoti Rao; Alok Singh

LAP Lambert Academic Publishing
2019
pokkari
Nanoscience refers to the science & discipline and nanotechnology refers the applied part of it including the engineering to control, manipulation and structuring the matter at an unimaginably small scale: nano scale. It is a relatively emerging field which has a potential to transform the field of dentistry. It offers novel opportunities for molecular disease imaging and technologically advanced clinical tools for oral therapeutic intervention. Nanotechnology in Periodontics has significant potential to yield new generation of mouthwashes, nanoscale characterization of biocompatible implants, tooth hypersensitivity and plaque management therapies. However, Nanodentistry still faces many significant challenges in realizing its tremendous potential.
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Fundamentals of Automata Theory and Compiler Construction

Fundamentals of Automata Theory and Compiler Construction

Narendra Kumar; Santosh Kumar Sharma; Alok Agarwal; Er. Mayank Kumar Jain

TechSar Pvt. Ltd
2022
nidottu
This book divided in eleven chapters, in the first chapter describes basics of a compiler, its definition and its types. It also includes the need of a compiler. The second chapter deals with phases of compiler, frontend and book end of compiler, single pass and multiphase compiler; Chapter three covers role of logical analyzer, description of tokens, automata, the fourth chapter presents syntax analyzer, grammar, LMD, RMD, passing techniques. Fifth chapter gives syntax directed translation, syntax tree, attributes such as synthesis and inherited. Chapter six deals with type checking, its definition, dynamic type checking and equivalence of it, function overloading and parameter passing. Chapter seven covers run time environment storage allocation techniques, symbol table. Chapter eight presents intermediate code generators, techniques of ICG, conversion. Chapter nine deals with code generation, basic blocks, flow graph, peephole optimization while chapter ten is on code optimization, that contains optimization of basic blocks, reducible flow graph, data flow analysis and global analysis. Chapter eleven one-pass compiler, compiler, its structure, STD rules and passing are described.
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