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1000 tulosta hakusanalla Michael G Rossmann

Selected Papers Of Michael G Rossmann With Commentaries: The Development Of Structural Biology

Selected Papers Of Michael G Rossmann With Commentaries: The Development Of Structural Biology

Michael G Rossmann

World Scientific Publishing Co Pte Ltd
2014
sidottu
About 50 publications out of more than 500 have been selected from the work of Michael Rossmann covering the years from 1958 to 2012. These include his early work with Max Perutz on hemoglobin and the first protein structures to his current work on the structures of small icosahedral and large polymorphic viruses. These papers describe not only some of the first protein and virus structures, but also the crystallographic and electron microscopic technologies. Furthermore, the author's interests include evolution and protein folding.The selected papers are a personal history of structural biology and especially of structural virology. The papers describe many of the basic techniques of structural biology such as isomorphous replacement, anomalous dispersion of X-rays, the molecular replacement method, X-ray diffraction data processing and combining crystallographic data with electron microscopic images.The book covers much of the historical development of the modern flourishing field of structural biology in terms of the authors' own contributions.
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Caught By Viruses

Caught By Viruses

Michael G Rossmann

WORLD SCIENTIFIC PUBLISHING CO PTE LTD
2022
sidottu
The current book attempts to give a glimpse of the scientific life of Michael Rossmann. The book begins with his very interesting and moving autobiography. His enormous energy must have been evident already from early childhood when he and his mother had to emigrate from Nazi-Germany to England, via The Netherlands. Starting school with a new language was a challenge that he managed well with the assistance of understanding teachers. Crystallography soon became the tool to explore new worlds, unknown to everybody. With a skill for mathematics, he realized that the transform of a molecular structure in the diffraction pattern could be used for analysis of both symmetry and structural relationships. This method, molecular replacement (MR, also the initials of his name) became one of his great successes of his career. The previous book by him in this series (Selected Papers by Michael G Rossmann with Commentaries) covers his main contributions in this area.With an interest in symmetry, viruses became obvious objects to study. Rossmann attacked these monstrously large molecular assemblies with his unfailing energy and his appetite for real challenges. The amazing variation of molecular arrangements with icosahedral symmetry is truly amazing. This book includes a selection of reports of the structures of some giant viruses. As always, knowing the structure enhances the understanding of function greatly, in the case of viruses the mechanism of infection is a key problem. Rossmann has contributed many central insights in this area.Thus, this book is of interest both as an interesting personal story but also for research into viruses that repeatedly plague all living organisms on the planet, right now in the form of the corona virus pandemic.
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Franchise Bible

Franchise Bible

Rick Grossmann; Michael J. Katz

Entrepreneur Press
2021
pokkari
The Insider’s Guide to Buying a Franchise or Franchising Your Business In this easy-to-read guide, franchise expert Rick Grossmann and franchise attorney Michael J. Katz impart decades-worth of insight and advice on what it takes to make your franchise operation successful. Grossmann and Katz share expert tutorials, tricks of the trade, and access to sample franchise documents, checklists, and questionnaires designed to get you organized, support you through the process and get your new franchise off the ground. If you’re thinking of buying a franchise, you’ll learn how to: Determine if running a franchise is right for you Navigate franchise disclosure documents and agreements Identify the signs of a good franchise opportunity If you’re thinking of franchising your existing business, you’ll learn how to: Pick the best method for expanding your business Understand the keys to establishing a successful franchise system Evaluate potential franchisees and grow your franchise Whether you want to buy a franchise or franchise your own business you’ll learn what to expect, how to move forward, and how to avoid costly mistakes--making Franchise Bible required reading.
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Determinants of Health

Determinants of Health

Michael Grossman

Columbia University Press
2017
sidottu
This collection of Michael Grossman's most important papers adds essential background and depth to his work on economic-based determinants of public health. Grossman organizes his essays into four categories and includes an introduction to each section that addresses the issues covered and the larger stakes of his work. An afterword discusses the effect of Grossman's approach to subsequent research on health economics and the work others have done to advance and extend his innovative perspective. Determinants of Health begins with a section on the theoretical underpinnings and empirical results of Grossman's groundbreaking health economics model, first introduced in the 1970s. It follows with sections on the relationship between health and schooling; determinants of infant health, with a special emphasis on public policies and programs; and the economics of unhealthy behaviors. These essays explain how the economic choices people make influence health and health behaviors. Grossman treats health as a form of human capital, and he shows that public policies and programs that determine the price and availability of key inputs have critical effects on outcomes ranging from birthweight and infant mortality to cigarette smoking, alcohol abuse, illegal drug use, and obesity. Grossman's approach has led to a major stream of literature in the field with contributions by the world's leading health economists, including Joseph Newhouse, Jonathan Gruber, Amy Finkelstein, Michael Greenstone, and David Cutler. His clarity on the economic decisions that lead people to make good or poor health choices is immensely valuable to the debate over how we spend on and legislate health.
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The Demand for Health

The Demand for Health

Michael Grossman

Columbia University Press
2017
sidottu
A seminal work in health economics, Michael Grossman's The Demand for Health introduced a new theoretical model for determining the health status of the population when first published in 1972. His work uniquely synthesized economic and public health knowledge and catalyzed a vastly influential body of health economics literature. It is well past time to bring this important work back into print. Grossman bases his approach on Gary S. Becker's household production function model and his theory of investment in human capital. Consumers demand health, which can include illness-free days in a given year or life expectancy, and then produce it through the input of medical care services, diet, other market goods and services, and time. Grossman also treats health and knowledge as equal parts of the durable stock of human capital. Consumers therefore have an incentive to invest in health to increase their earnings in the future. From here, Grossman examines complementarities between health capital and other forms of human capital, the most important of which is knowledge capital earned through schooling and its effect on the efficiency of production. He concludes that the rate of return on investing in health by increasing education may exceed the rate of return on investing in health through greater medical care. Higher income may not lead to better health outcomes, as wealth enables the consumption of goods and services with adverse health effects. These are some of the major revelations of Grossman's model, findings that have great relevance as we struggle to understand the links between poverty, education, structural disadvantages, and health.
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The Demand for Health

The Demand for Health

Michael Grossman

Columbia University Press
2017
pokkari
A seminal work in health economics, Michael Grossman's The Demand for Health introduced a new theoretical model for determining the health status of the population when first published in 1972. His work uniquely synthesized economic and public health knowledge and catalyzed a vastly influential body of health economics literature. It is well past time to bring this important work back into print. Grossman bases his approach on Gary S. Becker's household production function model and his theory of investment in human capital. Consumers demand health, which can include illness-free days in a given year or life expectancy, and then produce it through the input of medical care services, diet, other market goods and services, and time. Grossman also treats health and knowledge as equal parts of the durable stock of human capital. Consumers therefore have an incentive to invest in health to increase their earnings in the future. From here, Grossman examines complementarities between health capital and other forms of human capital, the most important of which is knowledge capital earned through schooling and its effect on the efficiency of production. He concludes that the rate of return on investing in health by increasing education may exceed the rate of return on investing in health through greater medical care. Higher income may not lead to better health outcomes, as wealth enables the consumption of goods and services with adverse health effects. These are some of the major revelations of Grossman's model, findings that have great relevance as we struggle to understand the links between poverty, education, structural disadvantages, and health.
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My Favourite Comedian

My Favourite Comedian

Michael Grossman

Michael Grossman
2019
pokkari
If you've ever been forced to go on a family holiday to the middle of nowhere, you know it's like getting a filling at the dentists. Everything from the long drives, boring day trips and beds that wage war on your spine, make it anything but a fun experience.The thought of a two week holiday with his mother and annoying sister did not excite Jake Archibald one bit. If they were taking him to Disneyland or Hawaii, he would have been totally up for it. But Brimbrilla? Even Google Earth has never heard of that place Besides, he already had enough on his mind with the separation of his parents and his weight issues. But this trip will prove to be anything but boring. From getting into a series of crazy situations to making friends with a stand-up comedian and a kid named Shakespeare, Jake is about to experience the adventure of a lifetime.
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Portraying the President

Portraying the President

Michael Grossman; Martha Joynt Kumar

Johns Hopkins University Press
1981
pokkari
The media have become principal actors on the American political scene. Politicians and their press secretaries release news items with one eye on the event and the other on the millions of voters who depend on the White House press corps to keep them informed about the workings of their government. Portraying the President explores the inner workings of the relationship between the White House and the press. Rather than emphasize the well-publicized sparring between inquisitive reporters and evasive administrative spokesmen intent on enhancing the President's public image, the authors stress the vast amount of cooperation between journalists and their sources. They point out the similarities of the White House-media relationship in recent administrations and suggest what shape it is likely to take in the future. The authors also address the key issues of information management and manipulation by both the administration and the press. Grossman and Kumar demonstrate that, whether a lower level staff member leaks a news item to elevate his own status or an official spokesman mentions a new policy proposal in order to gather support, the release of information to the White House press corps involves complicated strategies among a number of administrative personnel. Washington reporters, aware of some of these tactics, compensate by cultivating personal sources and trading information with officials. Nevertheless, the routine nature of White House reporting and the competitiveness of modern news organizations often trap the reporter into what has been called "pack journalism." Interviews with current and former White House reporters, including Bob Schieffer, Tom Brokaw, James Naughton, James Reston, and John Osborne, give Portraying the President an authentic, firsthand sound and feel. Comments from Ron Nessen, Gerald Rafshoon, Jody Powell, and other presidential spokesmen and advisors, give insight into White House operations during the Nixon, Ford, and Carter administrations. Portraying the President provides information vital to an appreciation of the modern American political system. Its thought-provoking conclusions will be of interest political scientists, media specialists, and anyone interested in current affairs.
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Forensic Chemistry

Forensic Chemistry

Michael Grossman

De Gruyter
2021
isokokoinen pokkari
FORENSIC CHEMISTRY FUNDAMENTALS strives to help scientists & lawyers,& students, understand how their two disciplines come together for forensic science,in the contexts of analytical chemistry & related science more generally, and thecommon law systems of Canada, USA, UK, the Commonwealth.In this book, forensics is considered more generally than as only for criminallaw; workplace health & safety, and other areas are included. And, two issues ofCanadian legal process are argued as essays in the fi nal two chapters.
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Forensic Chemistry

Forensic Chemistry

Michael Grossman

De Gruyter
2026
isokokoinen pokkari
Fundamentals of Forensic Chemistry strives to help scientists & lawyers, & students, understand how their two disciplines come together for forensic science, in the contexts of analytical chemistry & related science more generally, and the common law systems of Canada, USA, UK, the Commonwealth. In this book, forensics is considered more generally than as only for criminal law; workplace health & safety, and other areas are included. And, two issues of Canadian legal process are argued as essays in the final two chapters.
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