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1000 tulosta hakusanalla Muhammad Raza Shah

Safety in the Chemical Laboratory and Industry

Safety in the Chemical Laboratory and Industry

Muhammad Raza Shah

Elsevier - Health Sciences Division
2023
nidottu
Safety in the Chemical Laboratory and Industry: A Practical Guide provides an authoritative reference on chemical safety procedures and the handling and disposal of chemicals at both the laboratory and industrial level. The book serves as a practical guide for laboratory workers and offers prudent guidelines for the development of regulatory policy for academic and non-academic organizations. The book stresses that all accidental injuries can be minimized if systems and attitudes are in place to prevent them and that to fully materialize a safety culture, even with improved technology, everyone should be mindful of maintaining a safe environment. This handbook will assist faculty, researchers, staff and students to provide a safe and healthy laboratory environment to teach, learn and conduct research.
Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy

Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy

Muhammad Raza Shah; Muhammad Imran; Shafi Ullah

Elsevier Science Publishing Co Inc
2019
nidottu
Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy reviews the principles and applications of nanocarriers for targeted drug delivery. Drug targeting involves active and passive strategies that exploit both the use of ligands for interactions and the physical and chemical properties of nanocarriers and micro-environments at target sites. Multidrug resistance and adverse side effects associated with anticancer drugs have attracted greater scientific attention and led formulation scientists to specifically target these drugs to target sites. Nanocarriers like liposomes, niosomes, gold nanorods, carbon nanotubes, and micelles are discussed for the delivery of drugs to specific disease sites. This is an important reference source for researchers in the biomedical and biomaterials fields who want to gain an understanding on how nanotechnology is used for earlier diagnoses and more effective cancer treatment.
Nanocarriers for Organ-Specific and Localized Drug Delivery

Nanocarriers for Organ-Specific and Localized Drug Delivery

Muhammad Raza Shah; Muhammad Imran Malik; Shafi Ullah

Elsevier Science Publishing Co Inc
2022
nidottu
Organ-specific drug delivery is aimed at achieving increased concentration of therapeutic molecules at target sites with minimum side effects on other healthy tissues. Similarly, drug-specific delivery to some vital organs, such as the brain, lungs, heart and kidneys remains a challenging task for the formulation scientists. Oral delivery of most of the commercially available life-saving drugs has also been impeded by various physio-chemical and biological barriers. These advancements in nanotechnology have led to the development of various pharmaceutical nanocarriers. Nanocarriers for Organ-Specific and Localized Drug Delivery summarizes targeted drug delivery systems and approaches to the major organs of the body. The book shows how drugs can be specifically targeted to the pathological area within an organ in a viable way. Employing pharmaceutical nanocarriers for drug delivery targeted to specific organs of the body requires a comprehensive knowledge of the disease site’s pathophysiology as well as physical, chemical and pharmaceutical techniques for modification or functionalization of the nanocarriers. Combining theoretical principles and practical applications of various nanocarriers for organ-specific drug delivery, this is an important reference source for all those seeking to increase their understanding of how pharmaceutical nanocarriers are being used to create more efficient drug delivery systems.
Lipid-Based Nanocarriers for Drug Delivery and Diagnosis

Lipid-Based Nanocarriers for Drug Delivery and Diagnosis

Muhammad Raza Shah; Muhammad Imran; Shafi Ullah

William Andrew Publishing
2017
nidottu
Lipid-Based Nanocarriers for Drug Delivery and Diagnosis explores the present state of widely used lipid-based nanoparticulate delivery systems, such as solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), nanoliposomes, micelles, nanoemulsions, nanosuspensions and lipid nanotubes. The various types of lipids that can be exploited for drug delivery and their chemical composition and physicochemical characteristics are reviewed in detail, along with their characterization aspects and effects of their dimensions on drug delivery systems behavior in-vitro and in-vivo. The book covers the effective utilization of these lipids based systems for controlled and targeted delivery of potential drugs/genes for enhanced clinical efficacy.
Stimuli-Responsive Nanocarriers for Targeted Drug Delivery

Stimuli-Responsive Nanocarriers for Targeted Drug Delivery

Muhammad Raza Shah; Tooba Jabri; Maria Khalid

Elsevier - Health Sciences Division
2024
nidottu
Stimuli-Responsive Nanocarriers for Targeted Drug Delivery presents a comprehensive overview of the most significant physical and chemical stimuli-responsive drug delivery systems. This book reviews targeted and controlled drug delivery systems and how nanocarriers can be used to improve the pharmacokinetics of drugs in biological systems, such as increasing utilization rate and reducing toxicity and side effects. After a key introduction to the topic, a range of nanocarrier types is assessed before exploring the clinical translation challenges and considerations involved. This book is a useful resource for researchers and postgraduate students in the fields of materials science, nanotechnology, pharmaceutical science, and medicinal chemistry.
a-Tertiary Amines en Route to Natural Products

a-Tertiary Amines en Route to Natural Products

Abdul Hameed; Mariya Al-Rashida; Muhammad Raza Shah

Elsevier Science Publishing Co Inc
2021
nidottu
a-Tertiary Amines en Route to Natural Products presents the multistep synthesis of natural products using schematic diagrams. This approach provides a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. The book covers the class of natural products bearing the a,a-disubstituted a-amino acid motif. Featured natural product molecules include Altemicidin, Amathaspiramide (A-F), Kaitocephalin, Lactacystin, Salinosporamide, Manzacidins (A,C), Neooxazolomycin, Sphingofungins (E,F), (1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid (ACPD), Total synthesis of cephalotaxine and related molecules, a-amino acids based natural products, a amino acid based natural products and Tetrodotoxin. This book is ideal for chemists working in the area of organic synthesis, especially those who are involved in the development of new, efficient and novel methodologies for natural product synthesis.
Indole Alkaloids

Indole Alkaloids

Maliha Uroos; Abdul Hameed; Sadia Naz; Muhammad Raza Shah

Elsevier - Health Sciences Division
2022
nidottu
Indole Alkaloids: Spirooxindole details the multistep synthesis of natural products using schematic diagrams, providing a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. As a volume in the Visual Guides to Natural Product Synthesis series, this book presents the schematic total syntheses of natural products containing a “spirooxindole? core structure. It covers spirooxindole molecules through visual diagrams, highlighting key steps involved in total, formal and semi-syntheses. Sections cover Brevianamide A and B, Citrinadin A and B, Coerulescine and Horsfiline, Elacomine and Isoelacomine, Gelsemine, Paraherquamide A and B, Rynchophylline, Isorynchophylline, and more. Visual layouts provide quick-and- easy access to developed synthetic routes towards the targeted spirooxindoles.
Polymeric Nanoparticles for Bovine Mastitis Treatment

Polymeric Nanoparticles for Bovine Mastitis Treatment

Ali Haider; Muhammad Ikram; Iram Shahzadi; Muhammad Asif Raza

Springer International Publishing AG
2023
sidottu
This book features an in-depth examination of the ongoing problem of bovine mastitis and the potential solutions offered by polymer nanoparticles. With extensive research and analysis, the book delves into the causes and consequences of bovine mastitis, including the shift in the relevance of various infections and the increasing problem of antibiotic resistance. The authors explore the use of nanoparticles as a potential alternative to traditional antibiotics and the importance of tailoring their characteristics for specific uses. Detailed discussions of the pros and cons of different manufacturing procedures and characterizations of bovine mastitis, drug-resistant bacteria, and resistance development make this monograph an invaluable resource for researchers and experts in the field of veterinary medicine, and an excellent resource for those interested in investigating the viability of nano-materials as future antibiotic alternatives.
Polymeric Nanoparticles for Bovine Mastitis Treatment

Polymeric Nanoparticles for Bovine Mastitis Treatment

Ali Haider; Muhammad Ikram; Iram Shahzadi; Muhammad Asif Raza

Springer International Publishing AG
2024
nidottu
This book features an in-depth examination of the ongoing problem of bovine mastitis and the potential solutions offered by polymer nanoparticles. With extensive research and analysis, the book delves into the causes and consequences of bovine mastitis, including the shift in the relevance of various infections and the increasing problem of antibiotic resistance. The authors explore the use of nanoparticles as a potential alternative to traditional antibiotics and the importance of tailoring their characteristics for specific uses. Detailed discussions of the pros and cons of different manufacturing procedures and characterizations of bovine mastitis, drug-resistant bacteria, and resistance development make this monograph an invaluable resource for researchers and experts in the field of veterinary medicine, and an excellent resource for those interested in investigating the viability of nano-materials as future antibiotic alternatives.
Bewertung von Tomaten-Genotypen auf NaCl-Toleranz

Bewertung von Tomaten-Genotypen auf NaCl-Toleranz

Muhammad Raza

Verlag Unser Wissen
2021
pokkari
Die urspr ngliche Forschung, die durchgef hrt wurde, um die Toleranz von Tomaten-Genotypen gegen ber dem Salzgehalt zu berpr fen. Es wurde die Hypothese aufgestellt, dass kultivierte Tomaten- und fortschrittliche Tomatenlinien die F higkeit haben, einen h heren Salzgehalt zu tolerieren, insbesondere in einem kritischen Stadium der Setzlingsetablierung. Genotypen k nnen einen unterschiedlichen morpho-physiologischen Mechanismus der Salztoleranz bei gleichem oder unterschiedlichem Salzgehalt aufweisen. Ergebnisse, die in Zusammenarbeit mit der Hypothese gefunden wurden, und verschiedene morpho-physiologische Mechanismen der Toleranz, die bei unterschiedlichem Salzstress aufgedeckt wurden. Die Z chtung auf Salztoleranz basiert vollst ndig auf der Identifizierung eines bestimmten Merkmals, das das Keimplasma unter salzhaltigen Bedingungen produktiver macht. Botaniker und Pflanzenz chter k nnten identifizierte salztolerante und salzempfindliche Linien f r n chste pr zise Experimente in Bezug auf Morphologie, Physiologie, Proteomik, Transkriptomik, biochemische und genetisch basierte Studien verwenden. Die meisten Landwirte in Entwicklungsl ndern sind mit vielen Umweltfaktoren konfrontiert, die zu Stress f hren, und das unterschiedlichste Problem bei jeder Kultur ist der Salzgehalt. F r Landwirte w re es also profitabel, die Ergebnisse dieser Forschung zu nutzen und Ziele zu verfolgen.
Évaluation des génotypes de tomates pour la tolérance au NaCl
La recherche originale men e pour v rifier la tol rance des g notypes de tomates la salinit . Il a t mis l'hypoth se que la tomate cultiv e et les lign es de tomates avanc es ont la capacit de tol rer une salinit plus lev e, en particulier un stade critique de l' tablissement des plantules. Les g notypes peuvent avoir un m canisme morpho-physiologique diff rent de tol rance au sel des niveaux de salinit identiques ou diff rents. R sultats trouv s en collaboration avec l'hypoth se et diff rents m canismes morpho-physiologiques de tol rance r v l s diff rents niveaux de stress salin. La s lection pour la tol rance au sel est totalement bas e sur l'identification d'un caract re particulier qui rend le mat riel g n tique plus productif dans des conditions salines. Les botanistes et les s lectionneurs pourraient utiliser des lign es identifi es tol rantes et sensibles au sel pour la prochaine exp rimentation pr cise en ce qui concerne la morphologie, la physiologie, la prot omique, la transcriptomique, les tudes biochimiques et g n tiques. La plupart des agriculteurs des pays en d veloppement sont confront s de nombreux facteurs environnementaux qui entra nent des stress et le probl me le plus divers pour chaque culture est la salinit . Ainsi, il serait rentable pour les agriculteurs d'utiliser les r sultats de cette recherche et de suivre les objectifs.
Valutazione dei genotipi di pomodoro per la tolleranza al NaCl
La ricerca originale condotta per verificare la tolleranza dei genotipi del pomodoro alla salinit . stato ipotizzato che le linee di pomodoro coltivato e di pomodoro avanzato abbiano la capacit di tollerare una salinit pi elevata, in particolare in una fase critica dell'insediamento delle piantine. I genotipi possono avere un diverso meccanismo morfo-fisiologico di tolleranza al sale allo stesso oa diversi livelli di salinit . Risultati trovati in collaborazione con l'ipotesi e diversi meccanismi morfo-fisiologici di tolleranza rivelati a vari livelli di stress salino. L'allevamento per la tolleranza al sale si basa totalmente sull'identificazione di un particolare tratto che rende il germoplasma pi produttivo in condizioni saline. Botanici e coltivatori di piante potrebbero utilizzare linee identificate tolleranti al sale e sensibili al sale per la successiva sperimentazione precisa per quanto riguarda la morfologia, la fisiologia, la proteomica, la trascrittomica, gli studi biochimici e genetici. La maggior parte della comunit agricola nei paesi in via di sviluppo sta affrontando molti fattori ambientali che portano a stress e il problema pi diverso per ogni coltura la salinit . Quindi, sarebbe vantaggioso per gli agricoltori utilizzare i risultati di questa ricerca e perseguire gli obiettivi.
Avaliação de genótipos de tomate para tolerância a NaCl

Avaliação de genótipos de tomate para tolerância a NaCl

Muhammad Raza

International Book Market Service Ltd
2021
pokkari
A pesquisa original conduziu para verificar a toler ncia de gen tipos de tomate contra a salinidade. Foi hipotetizado que o tomate cultivado e as linhagens de tomate avan ado t m a capacidade de tolerar salinidade mais alta, particularmente em um est gio cr tico de estabelecimento da muda. Os gen tipos podem ter um mecanismo morfo-fisiol gico diferente de toler ncia ao sal no mesmo ou em diferentes n veis de salinidade. Resultados encontrados em colabora o com a hip tese e diferentes mecanismos morfo-fisiol gicos de toler ncia revelados em v rios n veis de estresse salino. O melhoramento para toler ncia ao sal totalmente baseado na identifica o de um tra o particular que torna o germoplasma mais produtivo em condi es salinas. Bot nicos e criadores de plantas podem fazer uso de linhagens tolerantes e suscet veis ao sal identificadas para a pr xima experimenta o precisa em rela o morfologia, fisiologia, prote mica, transcript mica, estudos bioqu micos e gen ticos. A maior parte da comunidade agr cola dos pa ses em desenvolvimento est enfrentando uma s rie de fatores ambientais que levam ao estresse e o problema mais diverso para cada cultura a salinidade. Portanto, seria lucrativo para os agricultores usar os resultados desta pesquisa e seguir os objetivos.