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957 tulosta hakusanalla Winifred G. Helmes

John a. Johnson

John a. Johnson

Winifred G. Helmes

University of Minnesota Press
1949
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John A. Johnson was first published in 1949. Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible, and are published unaltered from the original University of Minnesota Press editions.The first native-born governor of Minnesota, and the only Democrat to have been elected to that office three times, was also the first Minnesotan to have a presidential nomination within his grasp.This study of a man who was, perhaps, the state's most beloved chief executive is a warm, fast-moving personal biography and an engrossing piece of political history.The issues, personalities, shifting political currents, and party cleavages, state and national, of the early 1900s live again in the full recounting of the political campaigns of that era. One chapter is devoted to the 1908 Democratic National Convention at which Johnson's name was place in nomination for the presidency—the convention which chose William Jennings Bryan as its standard-bearer for the third and last time.Johnson was a man of buoyant spirit and great personal charm, and the story of his life again dramatizes the American tradition that by force of character a man can lift himself from the humblest beginnings. At the time of his death in 1909 the warships in New York harbor dropped their flags to half-mast, and hundreds of memorial services were held throughout the nation. Many believed that, had he lived, Johnson would have won the presidential nomination and election in 1912.
Expert Obedience Training for Dogs

Expert Obedience Training for Dogs

Winifred G. Strickland

John Wiley Sons Inc
2003
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The Latest Edition of a Classic Dog Training Book Learn how to communicate more effectively with your dog using the time-tested training method of the most successful Obedience competitor in history. Winifred Strickland s humane, commonsense approach to dog training applies to all breeds of dogs, large and small. And now it s updated to include training for the latest AKC Obedience exercises. Complete with helpful training tips, answers to frequently asked questions, and more than 170 photographs, this is an indispensable resource for everyone pet owners, Novice competitors, Open enthusiasts, Utility contenders, and Obedience instructors.A Howell Dog Book of Distinction
Calcium-Antagonisten

Calcium-Antagonisten

Winifred G. Nayler

Springer-Verlag Berlin and Heidelberg GmbH Co. K
1989
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Dieses Buch gibt einen hervorragenden Überblick über den Stand der wissenschaftlichen Forschungen auf dem Gebiet der Pharmakologie der Calcium-Antagonisten. Die Pharmakokinetik der verschiedenen Calcium-Antagonisten wird ebenso beschrieben, wie die Anwendung in der Praxis bei den verschiedensten Erkrankungen des Herz-Kreislauf-Systems. Nebenwirkungen, Risiken und Kontraindikationen sind ein weiteres wichtiges Thema. Zum Schluß wird ein Ausblick auf die Zukunft dieses vielseitigen Medikamentes gegeben.
Second Generation of Calcium Antagonists

Second Generation of Calcium Antagonists

Winifred G. Nayler

Springer-Verlag Berlin and Heidelberg GmbH Co. K
1991
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"Another damned, thick, square book! Always scribble, scribble, scribble! Eh! Mr. Gibbon?" From the Literary Memoirs of Willi­ am, DUKE OF GLOUCESTER, 1743-1805 The foreword of any book is probably the most difficult to write -not only because it stands at the beginning of an exercise in writing and logic but because it is in this chapter that areader can expect to find a clear and unambiguous explanation of the author's reason for writing the book and why some subject matter has been included and other subject matter excluded. Potential readers ofthis book may not have an inclination to question why some subject matter has been excluded but instead may wonder why another book on calcium antagonists has been published. However, it is arguable with some force that there have been at least three recent developments in the field of calcium antagonism which provide more than adequate support for the view that another book on this topic is warranted. These developments include: (i) an improved understanding of the chemical structure, mode of action and architecture of the voltage-activated, calcium antagonist-sensitive calcium channels and their associated calcium-antagonist specific binding sites; (ii) a more accurate appreciation ofhow and when the calcium antagonists should be used in the management of a variety of clinical dis orders including cerebral ischaemia atherosclerosis, "mild" ischaemic heart disease, ventricular hyper­ trophy, impaired ventricular relaxation and hypertension (to name but a few), and (iii) the emergence of a second generation of calcium antagonists.
Calciumantagonisten der zweiten Generation

Calciumantagonisten der zweiten Generation

Winifred G. Nayler

Springer-Verlag Berlin and Heidelberg GmbH Co. K
1992
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"Schon wieder so ein verdammtes, dickes, spießiges Buch! Immer kritzeln, kritzeln, kritzeln, nicht wahr, Mr. Gibbon!" Aus den Literarischen Memoiren von Herzog Wilhelm von Gloucester, 1743-1805 Bei jedem Buch ist das Vorwort wahrscheinlich das Schwierigste. Nicht nur weil es am Beginn einer Übung im Schreiben und im folgerichtigen Denken steht, sondern weil der Leser an dieser Stelle eine eindeutige Erklärung dafür erwarten kann, warum das Buch überhaupt geschrie­ ben wurde und warum manche Themen besprochen, andere hingegen weggelassen wurden. Mancher Leser wird sich vielleicht keine Gedanken darüber machen, warum der eine oder andere Punkt nicht erwähnt wurde; er wird sich vielmehr fragen, warum schon wieder ein Buch über Calciumantagoni­ sten erscheint. Ich glaube aber, es kann mit Fug und Recht behauptet werden, daß auf diesem Gebiet in der letzten Zeit zumindest drei Ent­ wicklungen zu verzeichnen waren, welche die Veröffentlichung eines neuen Buches zu diesem Thema unbedingt gerechtfertigt erscheinen las­ sen: I. Wir wissen heute mehr über die chemische Struktur, die Wirkungs­ weise und den Aufbau der spannungsempfindlichen, auf Calcium­ antagonisten ansprechenden Calcium-Kanäle und ihre für Calcium­ antagonisten spezifischen Bindungsstellen. II. Die Anwendungsmöglichkeiten von Calciumantagonisten zur Be­ handlung einer Vielfalt von Erkrankungen wie zerebrale Ischämie, Atherosklerose, "leichte" ischämische Herzkrankheit, Linksherz­ hypertrophie, beeinträchtigte ventrikuläre Relaxation und Hyper­ tonie, um nur einige zu nennen, können heute besser beurteilt wer­ den. 111. Eine zweite Generation von Calciumantagonisten ist jetzt verfügbar.
Amlodipin

Amlodipin

Winifred G. Nayler

Springer-Verlag Berlin and Heidelberg GmbH Co. K
1993
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Die Entwicklung von Calciumantagonisten wurde erst k}rzlich als einer der gr ten Fortschritte in der Therapie von kardiovaskul{ren Erkrankungen in der 2. H{lfte des 20. Jahrhunderts beschrieben. Obwohl die Entwicklung dieser Medikamente bereits Mitte der sechziger Jahre begann, werden die therapeutischen Mglichkeiten erst seit kurzem genutzt. Die Information, diein diesem Buch geboten wird, ist zusammengestellt, um das Interesse des Lesers an dem langwirksamen Calciumantagonisten Amlodipin zu wecken. Es werden sowohl Eigenschaften von Amlodipin beschrieben als auch Vorteile dieses Therapeutikums im Vergleich zu anderen Calciumantagonisten herausgearbeitet. Das Buch ist besonders interessant f}r klinisch t{tige [rzte, die derartige Medikamente verschreiben und eine optimale Therapieihrer Patienten anstreben.
Amlodipine

Amlodipine

Winifred G. Nayler

Springer-Verlag Berlin and Heidelberg GmbH Co. K
1993
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"Those who choose to increase their knowledge still further by reading ... will discover an exciting new world. " NOEL WHITTAKER, in "Making Money Made Simple" 1989. The development of calcium antagonists has recently been described as representing "one of the major advances in cardiovascular thera­ peutics of the latter half of the twentieth century" (Braunwald, 1990). However, although the development of these drugs started in the mid­ nineteen sixties it is only recently that their real potential has begun to be appreciated. Even now the calcium antagonist saga is not complete, since new compounds continue to appear and new therapeutic applica­ tions emerge. Based on the experience gained in the clinics in which these drugs have been used recognition is being given now to the need to improve upon the prototypes of the group. Such improvement is resulting in the development and production not only of long-acting formulations of the prototypes (nifedipine, verapamil and diltiazem) but also of new calcium antagonists with improved tissue selectivity, potency and duration of action. To those of us who are interested in this field such a development is both exciting and rewarding. As far as the clinicians who prescribe these drugs are concerned the long-acting nature of some of the newer calcium antagonists should make the satisfactory management of their patients an achievable goal.
The Endothelins

The Endothelins

Winifred G. Nayler

Springer-Verlag Berlin and Heidelberg GmbH Co. K
2012
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"What we call the beginning is often the end, and to make an end is to make a beginning. The end is where we start from." T. S. ELIOT, "Geroniton" The discovery of endothelin-l was both an end and a beginning. It is an end because this discovery has started a plethora of investigations as to endothe1in's sites of production, mode of action, it's normal and abnormal physiological role and its involvement in a variety of pathological conditions ranging from renal failure to myocardial infarction, cardiac hypertrophy, hyperten­ sion, cyclosporine induced toxicity, mental depression, renal failure, stress related illness, and even stroke and sudden death. It is a beginning because no one can foresee where the investigations will ultimately lead, or how they will end. The discovery of the endothelins was a very recent event and soon specialist books will start to appear dealing in detail with different aspects of their chemistry, physiological role and pathological importance. The present book is intended to act as a guide and primer for those who are becoming intrigued by the many endothelin­ related articles which are now appearing in the journals but who as yet have not had the time or opportunity to be caught up in the web of enthusiasm and excitement which is motivating those more directly involved in the field of research.
Studies on the Legend of the Holy Grail (Edition1)

Studies on the Legend of the Holy Grail (Edition1)

D K Broster and G Winifred Taylor

Alpha Editions
2024
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Chantemerle: A Romance of the Vendean War Step into the tumultuous world of the French Revolution with ""Chantemerle: A Romance of the Vendean War,"" a captivating tale of love, loyalty, and courage. Written by the talented duo D. K. Broster and G. Winifred Taylor, this enthralling novel transports readers to the heart of the Vendean uprising, where passion and peril intertwine. Follow the gripping journey of our protagonists as they navigate the treacherous landscape of war-torn France, where every decision could mean the difference between life and death. With richly drawn characters and a plot that keeps you on the edge of your seat, ""Chantemerle"" is a timeless story of resilience and hope against all odds. Out of print for decades, this literary gem has been lovingly republished by Alpha Editions, ensuring that both current and future generations can experience its magic. More than just a book, this is a collector's edition-a piece of history that belongs on every bookshelf. Don't miss your chance to own a piece of literary history. Dive into ""Chantemerle"" and let the romance and adventure sweep you away
The Vision Splendid BOOK III (Edition2024)

The Vision Splendid BOOK III (Edition2024)

D K Broster; G Winifred Taylor

Double 9 Books LLP
2024
nidottu
The Vision Splendid BOOK III by D. K. Broster and G. Winifred Taylor is a novel set in early 19th century England, focusing on the life of Horatia Grenville, a well-educated yet unmarried woman caught between personal aspirations and societal expectations. The story opens with Horatia in her tranquil garden, contemplating her desire for intellectual fulfillment while wrestling with the pressures to marry and conform to the traditional roles of women in her time. Raised as a parson's daughter, Horatia has been shaped by an unconventional upbringing that fosters her aversion to societal norms, particularly the expectation that women should prioritize marriage over personal ambition. As the novel unfolds, Horatia's internal struggles are complicated by the presence of Tristram Hungerford, a family friend who had once proposed to her. Their encounters reveal unspoken feelings and growing tensions, reflecting the societal shifts of the period. The narrative explores the conflict between individual desire and the traditional roles expected of women, blending themes of intellectual independence, love, and the evolving roles of women in the early 19th century. Through Horatia's journey, the novel examines the tension between personal growth and societal conformity.