A. John Camm

In recent years there has been considerable interest in the diagnosis and understanding of ventricular repolarisation, particularly the QT interval prolongation and abnormal T and T/U wave morphology associated with torsades de pointes. Advances in ion channel cloning have greatly improved our understanding of the role of ionic channels in mediating cardiac repolarisation. Unfortunately, it is increasingly recognised that a number of drugs, both those associated with altering repolarisation, and others for non-cardiac conditions can increase the propensity for polymorphic ventricular tachycardia, syncope and even ventricular fibrillation and sudden death. In this volume, arrhythmia specialists from St. George’s Hospital Medical School, London discuss the mechanisms behind QT prolongation and torsades de pointes. They focus particularly on the risk of individual cardiac and non-cardiac drugs in provoking long QT syndrome, providing a comprehensive review which will be useful for all electrophysiologists treating polymorphic ventricular tachycardias, and will expose important regulatory issues for pharmaceutical authorities and for the wider medical community.

Clinical Cardiology: Current Practice Guidelines Updated Edition is an essential tool for the busy clinician, offering succinct yet detailed access to the most recent trial and guideline data supporting practice and patient management in cardiology. ESC and ACC/AHA guidelines are continually updated and often overlap in their advice, making it difficult for the cardiologist to obtain a clear picture of the right way to diagnose and treat disease according to the latest evidence base. Written by leading authorities in the field, this book, together with its regularly-updated online version, provides a unique solution. The authors have scrutinized all available guidelines and research from both ACC/AHA and ESC on every clinical issue. The result is a rigorous examination of the implications of published guidance, illustrated by more than 600 easy-to-follow tables and 200 full-colour images, which reinforce key points and clarify difficult concepts. 87 comprehensive chapters explore the definition, epidemiology, pathophysiology, diagnosis and management of cardiac disease. Two new chapters examine the univentricular heart and venous thrombembolism. Each chapter encompasses the latest published research, followed by discussions of possible presentations and investigations, offering detailed insights for clinicians into best practice for diagnosis and treatment. Providing at-a-glance access to the best guidance in cardiology, this book offers a diagnosis and management toolkit which no practising cardiologist can afford to be without.

This handbook offers timely investigation of current pharmaceutical trends, clinical guidelines, novel treatments, and ongoing pipeline developments, including ground-breaking advances in the use of novel oral anticoagulants. ?Atrial fibrillation (AF) affects an estimated 1–2% of the population and is the most common cause of sustained cardiac arrhythmia. Critically, the number of patients developing AF is expected to double in the next five decades, leading to increased incidence of stroke, heart failure and other serious thromboembolic events.

There are many excellent textbooks that exist in the area of implantable devices for arrhythmia control. Few textbooks, however, provide a case study approach. Collectively, these workbooks provide an approach to problem solving an electrocardiographic interpretation for patients with permanent pacemakers and defibrillators. Volume 1 addresses patients with permanent pacemakers Volume 2 examines interactions between pacemakers and implantable defibrillators Volume 3 provides case studies of transtelephonic pacemakers electrocardiography Volume 4 provides more pacemaker and implantable defibrillator troubleshooting cases This volume takes a case-orientated approach, providing a diverse series of problems on a broad range of topics related to implantable defibrillators. The cases are divided into easy, moderate and complex according to their level of difficulty, allowing the reader to gauge their progress. This workbook is suitable for physicians, nurses, technicians, technologists and industry engineers, particularly those new to the field who are keen to learn in a practical way.

There are many excellent textbooks that exist in the area of implantable devices for arrhythmia control. Few textbooks, however, provide a case study approach. Collectively, these workbooks provide an approach to problem solving an electrocardiographic interpretation for patients with permanent pacemakers and defibrillators. Volume 1 addresses patients with permanent pacemakers Volume 2 examines interactions between pacemakers and implantable defibrillators Volume 3 provides case studies of transtelephonic pacemakers electrocardiography Volume 4 provides more pacemaker and implantable defibrillator troubleshooting cases This volume takes a case-orientated approach, providing a diverse series of problems on a broad range of pacing related topics. The cases are divided into easy, moderate and complex according to their level of difficulty, allowing the reader to gauge their progress. This workbook is suitable for physicians, nurses, technicians, technologists and industry engineers, particularly those new to the field who are keen to learn in a practical way.