Donald E. Greydanus

It is estimated that 86 million adult Americans have prediabetes and with that, a risk of developing T2DM (type 2 diabetes) within one in ten patients. About 29 million people have actual diabetes, most with T2DM. It was estimated in 2012 that about 208,000 people under the age of 20 have diabetes in the United States, but there is little data available on the prevalence of diabetes in the adolescent population. A recent study looking at 12-19 year olds from 2005-2014 found the prevalence of diabetes at 0.8%, with 28.5% undiagnosed and the prevalence of prediabetes 17.7%, more common among boys (22%) than girls (13.2%). With about 9% of the total US population having diabetes, this a public health issue of considerable proportions. In this book, the reader embarks on a journey through the medical history of the discovery and treatment of diabetes mellitus. It is the story of the human mind steadfastly seeking to understand its world a story worth telling again and again that has saved millions of lives from a premature death of misery in the 20th and now 21st century.

The Guest Editors have assembled expert authors to cover the full clinical span of the topic autism and autism spectrum disorders. An historical perspective of the evolution of the disorder opens the issue. Next, comprehensive coverage is given to an article on the definitions, diagnostic criteria, and clinical features of autism spectrum disorders. Other articles in the issue cover the relevant topics like epidemiology, genetic syndromes and genetic testing, early diagnosis and diagnostic evaluation, and neuroimaging and neurochemistry of autism. Authors also present information on tsocial skills for the autistic child, behavioral interventions, and transitioning the autistic child into adulthood, to name a few. This issue should be very well received by pediatricians.

Pediatric and Adolescent Psychopharmacology is reviewed in this issue of Pediatric Clinics, guest edited by Drs. Dilip Patel, Donald Greydanus, and Cynthia Feucht. Authorities in the field have come together to pen articles on Therapy in the Age of Pharmacology: Point-Counterpoint, Principles of Pharmacology and Neurotransmission, Complementary and Alternative Medicine in Pediatric Mental Health, Psychopharmacology of Anxiety Disorders, Psychopharmacologic Control of Aggression and Violence, Autistic Spectrum Disorders, Attention Deficit Hyperactivity Disorder, Psychopharmacology of Anorexia and Bulimia Nervosa, Psychopharmacology of Obesity, Psychopharmacology of Depression, Psychopharmacology of Pediatric Bipolar Disorders, Cognitive-Adaptive Disabilities, Psychopharmacology of Schizophrenia, Management of Psychotic States Induced by Medical Conditions, Substance Use and Abuse, Psychopharmacology of Tic Disorders, and Pharmacology of Sleep Disorders.

This issue of Pediatric Clinics, guest edited by Drs. Dilip Patel and Donald Greydanus, examines the topic of Adolescents and Sports. Authorities in the field have come together to pen articles on Pre-participation evaluation, Cardiovascular evaluation of young athletes, Medical conditions and sport participation, Management of the adolescent athlete with type 1 diabetes mellitus, Musculoskeletal conditions and sports participation, Stress fractures: Diagnosis and management, Computer-based neuropsychological evaluation of concussion, The female athlete, Doping: From drugs and supplements to genetics, Analgesics and anti-inflammatory medications in sports, Nutritional considerations for adolescent athletes, Resistance training guidelines for adolescents, Application of osteopathic manual medicine to treat sports injuries, and Physically and cognitively challenged athletes.