Freddy Bugge Christiansen

This textbook provides an authoritative introduction to both classical and coalescent approaches to population genetics. Written for graduate students and advanced undergraduates by one of the world's leading authorities in the field, the book focuses on the theoretical background of population genetics, while emphasizing the close interplay between theory and empiricism. Traditional topics such as genetic and phenotypic variation, mutation, migration, and linkage are covered and advanced by contemporary coalescent theory, which describes the genealogy of genes in a population, ultimately connecting them to a single common ancestor. Effects of selection, particularly genomic effects, are discussed with reference to molecular genetic variation. The book is designed for students of population genetics, bioinformatics, evolutionary biology, molecular evolution, and theoretical biology--as well as biologists, molecular biologists, breeders, biomathematicians, and biostatisticians. * Contains up-to-date treatment of key areas in classical and modern theoretical population genetics * Provides in-depth coverage of coalescent theory * Discusses genomic effects of selection * Gives examples from empirical population genetics * Incorporates figures, diagrams, and boxed features throughout * Includes end-of-chapter exercises * Speaks to a wide range of students in biology, bioinformatics, and biostatistics

EvolutionslAeren beskriver livets udvikling gennem Jordens historie og gor de sAereste fAenomener begribelige - fra bakteriers DNA i vores celler til smaborgermonogami hos solsorte og atmosfAerens indhold af ilt.Denne bog giver lAeseren et samlet overblik over den skelsAettende teori og dens udvikling. Linjen trAekkes fra gennembruddet med Charles Darwins hovedvAerk Arternes oprindelse i 1859 og frem til den molekylAere genetiks revolutionerende resultater i de seneste ar. Evolutionens historie og mekanismer, arvelighedens natur, konnets formering og evolutionAert bestemte adfAerdsmonstre forklares.SAerligt sAettes der fokus pa en ofte underbelyst konsekvens af Darwins ide om naturlig selektion eller survival of the fittest: Livets udvikling er uden mal, og mennesket er derfor ikke det ypperste resultat af en lang forAedlingsproces.

This textbook provides an authoritative introduction to both classical and coalescent approaches to population genetics. Written for graduate students and advanced undergraduates by one of the world's leading authorities in the field, the book focuses on the theoretical background of population genetics, while emphasizing the close interplay between theory and empiricism. Traditional topics such as genetic and phenotypic variation, mutation, migration, and linkage are covered and advanced by contemporary coalescent theory, which describes the genealogy of genes in a population, ultimately connecting them to a single common ancestor. Effects of selection, particularly genomic effects, are discussed with reference to molecular genetic variation. The book is designed for students of population genetics, bioinformatics, evolutionary biology, molecular evolution, and theoretical biology--as well as biologists, molecular biologists, breeders, biomathematicians, and biostatisticians. * Contains up-to-date treatment of key areas in classical and modern theoretical population genetics * Provides in-depth coverage of coalescent theory * Discusses genomic effects of selection * Gives examples from empirical population genetics * Incorporates figures, diagrams, and boxed features throughout * Includes end-of-chapter exercises * Speaks to a wide range of students in biology, bioinformatics, and biostatistics