Gurpreet Singh

Soft tissue simulants, essential for automotive and ballistic testing, medical, and surgical training, have traditionally relied on cadavers and animal tissues. However, their biomechanical properties change with time due to dehydration after death and the biomechanics of the animal models cannot be translated and compared with the human tissues. This book compiles various synthetic tissues used in these applications, addressing their characterization and industry-wide applications. While older simulants lack biofidelity, recent advancements in biofidelic soft tissue simulants offer promising alternatives, yet technology transfer remains limited. This book fills the gap by exploring each simulant's characteristics and current trends, facilitating their adoption in clinical and academic settings. These synthetic tissues have the potential to replace live tissues in surgical training, streamlining biosafety approvals. They also benefit academic researchers by reducing costs and time in biomechanical testing. Anticipated to be the first of its kind, this comprehensive reference book will showcase recent advancements in soft tissue simulant development, serving as a cornerstone text in tissue engineering & biomedical engineering, medical simulation, biomechanics, and related fields.

L'obiettivo di questo libro condividere con i lettori le indagini sperimentali sull'effetto dei parametri di taglio controllati, ossia la velocit di taglio, l'avanzamento, la profondit di taglio, la concentrazione del fluido da taglio e due fluidi da taglio con oli base diversi sulla rugosit superficiale (Ra) dell'acciaio EN8 o AISI 1040 durante l'operazione di tornitura, utilizzando il disegno degli esperimenti, il metodo di disegno personalizzato, l'analisi della varianza, i diagrammi di leva e il profilo di desiderabilit con il software JMP per studiare le caratteristiche delle prestazioni nell'operazione di tornitura CNC a umido. L'analisi rivela che la velocit di avanzamento ha l'effetto pi significativo sulla rugosit superficiale (Ra) e il valore della rugosit superficiale non differisce significativamente per i due diversi fluidi da taglio utilizzati.

L'objectif de ce livre est de partager avec les lecteurs les recherches exp rimentales sur l'effet des param tres de coupe contr l s, savoir la vitesse de coupe, la vitesse d'avance, la profondeur de coupe, la concentration du liquide de coupe et deux liquides de coupe avec des huiles de base diff rentes sur la rugosit de surface (Ra) de l'acier EN8 ou AISI 1040 pendant l'op ration de tournage en utilisant la conception des exp riences, la m thode de conception personnalis e, l'analyse de la variance, les diagrammes de levier et le profilage de d sirabilit en utilisant le logiciel JMP pour tudier les caract ristiques de performance dans l'op ration de tournage CNC sous arrosage. L'analyse r v le que la vitesse d'avance a l'effet le plus significatif sur la rugosit de surface (Ra) et que la valeur de la rugosit de surface ne diff re pas de mani re significative pour les deux diff rents fluides de coupe utilis s.

Ziel dieses Buches ist es, den Lesern die experimentellen Untersuchungen ber die Auswirkungen kontrollierter Schnittparameter, n mlich Schnittgeschwindigkeit, Vorschubgeschwindigkeit, Schnitttiefe, Schneidfl ssigkeitskonzentration und zwei Schneidfl ssigkeiten mit unterschiedlichen Grund len, auf die Oberfl chenrauheit (Ra) von EN8 oder AISI 1040 Stahl w hrend des Drehvorgangs mit Hilfe von Versuchsplanung, benutzerdefinierter Versuchsplanungsmethode, Varianzanalyse, Leverage Plots und W nschbarkeitsprofilierung unter Verwendung der JMP-Software zur Untersuchung der Leistungsmerkmale beim CNC-Nassdrehvorgang zu vermitteln. Die Analyse zeigt, dass die Vorschubgeschwindigkeit die gr te Auswirkung auf die Oberfl chenrauheit (Ra) hat und der Wert der Oberfl chenrauheit sich nicht signifikant f r zwei verschiedene verwendete K hlschmierstoffe unterscheidet.

O objetivo deste livro partilhar com os leitores as investiga es experimentais sobre o efeito dos par metros de corte controlados, nomeadamente a velocidade de corte, a taxa de avan o, a profundidade de corte, a concentra o do fluido de corte e dois fluidos de corte com diferentes leos de base na rugosidade da superf cie (Ra) do a o EN8 ou AISI 1040 durante a opera o de torneamento, utilizando o design de experi ncias, o m todo de design personalizado, a an lise de vari ncia, os gr ficos de alavancagem e o perfil de desejabilidade utilizando o software JMP para estudar as caracter sticas de desempenho na opera o de torneamento CNC em molhado. A an lise revela que a taxa de avan o tem o efeito mais significativo na rugosidade da superf cie (Ra) e que o valor da rugosidade da superf cie n o difere significativamente entre os dois fluidos de corte diferentes utilizados.

Soft tissue simulants, essential for automotive and ballistic testing, medical, and surgical training, have traditionally relied on cadavers and animal tissues. However, their biomechanical properties change with time due to dehydration after death and the biomechanics of the animal models cannot be translated and compared with the human tissues. This book compiles various synthetic tissues used in these applications, addressing their characterization and industry-wide applications. While older simulants lack biofidelity, recent advancements in biofidelic soft tissue simulants offer promising alternatives, yet technology transfer remains limited. This book fills the gap by exploring each simulant's characteristics and current trends, facilitating their adoption in clinical and academic settings. These synthetic tissues have the potential to replace live tissues in surgical training, streamlining biosafety approvals. They also benefit academic researchers by reducing costs and time in biomechanical testing. Anticipated to be the first of its kind, this comprehensive reference book will showcase recent advancements in soft tissue simulant development, serving as a cornerstone text in tissue engineering & biomedical engineering, medical simulation, biomechanics, and related fields.

This monograph brings forth biomechanical research methods and outcomes on human tissue experiments such as those of the brain and the heart under a single umbrella. Different mechanical characterization techniques employed in human tissue property estimation are presented in detail. The contents also focus on a hyperelastic constitutive model (e.g., Mooney-Rivlin, Ogden) for both isotropic and anisotropic tissue characterization. It also discusses energy dissipation in soft tissues and associated viscoelasticity. Human tissues, including skin, muscles, connective tissues, and tissues in all functional organs are listed and their mechanical properties are presented in detail. These tissue properties are indispensable for computational modeling of biological systems, validation of biomechanical tissue testing, medical simulation through development of artificial phantoms and surrogates, and testing of medical devices and interventions. This book will serve as a key reference forresearch in tissue engineering & biomedical engineering, medical simulation, biomechanics, finite element modeling of biological systems, biomaterials, biotechnology, implant and medical device development, and healthcare wearables.