J. Craig Venter

"Inspiring" (Telegraph) and "brimming with the excitement of discovery" (Siddhartha Mukherjee), a story of sailing the high seas in search of the ocean's microbiome and the genetic code of life. "A lively account of a groundbreaking exploration of the microbiome of the Earth's waters . . . Important and adventurous science on the high seas." --Kirkus Reviews Upon completing his historic work on the Human Genome Project, J. Craig Venter set out to sequence the genetic code of all life on Earth. Boarding the research vessel Sorcerer II, Venter traveled over 65,000 miles around the globe to sample ocean water and the microscopic life therein. From plant-like bacteria that get their energy from the sun to microbes whose genes shield them from ultraviolet light, his findings revealed the unimaginable complexity and diversity of evolution as well as the toll of human activity on the microbiome that nourishes life. In the face of unprecedented climate change, Venter and science writer David Ewing Duncan show how we can harness the microbial genome to develop alternative sources of energy, food, and medicine. A captivating story of exploration and discovery, The Voyage of Sorcerer II restores microbes to their rightful places as crucial partners in our evolutionary past and guides to our future.

A celebrated genome scientist sails around the world, collecting tens of millions of marine microbes and revolutionising our understanding of the microbiome that sustains us.

'An epic travelogue, brimming with the excitement of discovery. With characteristic panache, Venter unveils the teeming array of bacteria, viruses, and eukaryotes that crowd our planet's oceans' - Siddhartha Mukherjee'This page-turner gives . . . the thrill of seeing our planet's largest universe through the brilliant, intrepid eyes of the scientist who has done more than anyone to unlock the secrets of life' - Martine Rothblatt'A tour de force . . . Venter has expanded biology's horizons. This book explores microbial life on a global scale, providing cutting-edge solutions to problems of environmental change' - Aristides Patrinos'A ripping tale . . . to revolutionize our understanding of our bodies, the oceans, and the planet' - Jack Gilbert'An exhilarating account of how creative science is accomplished' - Sir Richard J. Roberts'[A] fascinating tour of Planet Microbe' - Bill McKibben'Venter and Duncan expand our scope of what it means to be alive' - Jamie Metzl'Inspiring ... change[s] our ideas of how biology is done' - TelegraphUpon completing his historic work on the Human Genome Project in 2002, J. Craig Venter declared that he would sequence the genetic code of all life on earth. Thus began a fifteen-year quest to collect DNA from the world's oldest and most abundant form of life: microbes. Boarding the Sorcerer II, a 100-foot sailboat turned research vessel, Venter travelled over 65,000 miles around the globe to sample ocean water and the microscopic life within.In this book, Venter and science writer David Ewing Duncan tell the remarkable story of these expeditions and of the momentous discoveries that ensued-of plant-like bacteria that get their energy from the sun, proteins that metabolize vast amounts of hydrogen, and microbes whose genes shield them from ultraviolet light. The result was a massive library of millions of unknown genes, thousands of unseen protein families, and new lineages of bacteria that revealed the unimaginable complexity of life on earth. Yet despite this exquisite diversity, Venter encountered sobering reminders of how human activity is disturbing the delicate microbial ecosystem that nurtures life on earth. In the face of unprecedented climate change, Venter and Duncan show how we can harness the microbial genome to develop alternative sources of energy, food, and medicine that might ultimately avert our destruction.A captivating story of exploration and discovery, this book restores microbes to their rightful place as crucial partners in our evolutionary past and guides to our future.

"Will undoubtedly shape our understanding of the global ecosystem for decades to come."--Siddhartha Mukherjee, author of The Emperor of All Maladies A celebrated genome scientist sails around the world, collecting tens of millions of marine microbes and revolutionizing our understanding of the microbiome that sustains us. Upon completing his historic work on the Human Genome Project, J. Craig Venter declared that he would sequence the genetic code of all life on earth. Thus began a fifteen-year quest to collect DNA from the world's oldest and most abundant form of life: microbes. Boarding the Sorcerer II, a 100-foot sailboat turned research vessel, Venter traveled over 65,000 miles around the globe to sample ocean water and the microscopic life within. In The Voyage of Sorcerer II, Venter and science writer David Ewing Duncan tell the remarkable story of these expeditions and of the momentous discoveries that ensued--of plant-like bacteria that get their energy from the sun, proteins that metabolize vast amounts of hydrogen, and microbes whose genes shield them from ultraviolet light. The result was a massive library of millions of unknown genes, thousands of unseen protein families, and new lineages of bacteria that revealed the unimaginable complexity of life on earth. Yet despite this exquisite diversity, Venter encountered sobering reminders of how human activity is disturbing the delicate microbial ecosystem that nurtures life on earth. In the face of unprecedented climate change, Venter and Duncan show how we can harness the microbial genome to develop alternative sources of energy, food, and medicine that might ultimately avert our destruction. A captivating story of exploration and discovery, The Voyage of Sorcerer II restores microbes to their rightful place as crucial partners in our evolutionary past and guides to our future.

Race, while drawn from the visual cues of human diversity, is an idea with a measurable past, an identifiable present, and an uncertain future. The concept of race has been at the center of both triumphs and tragedies in American history and has had a profound effect on the human experience. Race Unmasked revisits the origins of commonly held beliefs about the scientific nature of racial differences, examines the roots of the modern idea of race, and explains why race continues to generate controversy as a tool of classification even in our genomic age.Surveying the work of some of the twentieth century's most notable scientists, Race Unmasked reveals how genetics and related biological disciplines formed and preserved ideas of race and, at times, racism. A gripping history of science and scientists, Race Unmasked elucidates the limitations of a racial worldview and throws the contours of our current and evolving understanding of human diversity into sharp relief.

Synthetic biology involves the rational design and construction of biological components and systemsfrom genetic elements and metabolic pathways to entirely new organisms. Progress in this field has been rapid, and it promises to significantly expand our capabilities in biotechnology, medicine, and agriculture. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines the tools and techniques employed by synthetic biologists, how these may be used to develop new drugs, diagnostic approaches, food sources, and clean energy, and what the field of synthetic biology has taught us about natural living systems. The contributors discuss advances in DNA synthesis and assembly, genome editing (e.g., CRISPR/Cas9), and artificial genetic systems. Progress in designing complex genetic switches and circuits, expanding the genetic code, modifying cellular organization, producing proteins using cell-free systems, and developing biodesign automation tools is also covered. The authors also explore ways to produce new organisms and products that have particular attributesfor example, microbial "molecular factories," synthetic organs and tissues, and plants with novel traits. This volume is an essential resource for molecular, cell, and systems biologists who seek to engineer living systems for human benefit.

Race, while drawn from the visual cues of human diversity, is an idea with a measurable past, an identifiable present, and an uncertain future. The concept of race has been at the center of both triumphs and tragedies in American history and has had a profound effect on the human experience. Race Unmasked revisits the origins of commonly held beliefs about the scientific nature of racial differences, examines the roots of the modern idea of race, and explains why race continues to generate controversy as a tool of classification even in our genomic age. Surveying the work of some of the twentieth century's most notable scientists, Race Unmasked reveals how genetics and related biological disciplines formed and preserved ideas of race and, at times, racism. A gripping history of science and scientists, Race Unmasked elucidates the limitations of a racial worldview and throws the contours of our current and evolving understanding of human diversity into sharp relief.

Where did our search to understand life come from? And where will it take us?

Craig Venter is no ordinary scientist, and no ordinary man. He is the first human being ever to read their own DNA – and see the key to life itself. Yet in doing so, he rocked the establishment and became embroiled in one of the biggest controversies of our age. This is the story of his incredible life: from teenage rebel and Vietnam medic, to daredevil sailor and maverick researcher, whose race to unravel the sequence of the human genome made him both hero and pariah. Incorporating his own genetic make-up into his story, this is an electrifying portrait of a man who pushed back the boundaries of the possible.

The triumphant memoir of the man behind one of the greatest feats in scientific history Of all the scientific achievements of the past century, perhaps none can match the deciphering of the human genetic code, both for its technical brilliance and for its implications for our future. In A Life Decoded, J. Craig Venter traces his rise from an uninspired student to one of the most fascinating and controversial figures in science today. Here, Venter relates the unparalleled drama of the quest to decode the human genome?a goal he predicted he could achieve years earlier and more cheaply than the government-sponsored Human Genome Project, and one that he fulfilled in 2001. A thrilling story of detection, A Life Decoded is also a revealing, and often troubling, look at how science is practiced today.