Jill Barber

Macrolide antibiotics represent a class of natural macrocyclic products, one of the most clinically important antibiotics. Unfortunately, the production and development of new macrolide antibiotics are not represented enough in the pharmaceutical industry today. The intention of the book is therefore not only to be a teaching tool for students and experts, but also to draw the attention of the general public to this extremely useful, cheap and relatively unharmful effective anti-macrobials, and potential anti-malarials. The authors introduce the different classes of macrolides and their derivatives, principles of their biological activity, their structure and interactions with biological targets as well as synthetic methods to produce new macrolide antibiotics of similar or improved properties. Special emphasis was put on conjugates of macrolides with nucleobases or nucleosides with numerous applications; among them the most important remains the attempt to overcome bacterial resistance.

Westminster in Old Photographs gives a fascinating insight into the dramatic changes that have occurred in central London over the last 150 years. This fascinating collection of photographs provides an impression of the generations of people who lived and worked here in the late nineteenth and early twentieth centuries, and recalls houses, public buildings, shops, businesses and pubs that have vanished or been altered almost beyond recognition. The pioneering work of early photographers adds a new dimension to our record of the past and brings it vividly back to life. Their pictures document changes in transport and fashion and the evolving characters of streets and districts as they took on the form that is familiar today. The photographs also remember many famous events - funerals, demonstrations, coronations - when the nation's attention was focused firmly on Westminster.Jill Barber has chosen a memorable selection of rare photographs from the City of Westminster Archives Centre to produce this detailed and revealing account of the recent past in the historic centre of the capital. Her book will add to the knowledge, appreciation and enjoyment of all those who take an interest in the development of this remarkable area and the history of London as a whole.