Joseph F. Goldberg

Information about new psychotropic drugs, a summary of advances in knowledge about identifiable risk factors for adverse effects, and updated recommendations on viable "antidote" management strategies—including novel pharmacotherapies for tardive dyskinesia and newer agents for weight loss—are among the features of this new, second edition of Managing the Side Effects of Psychotropic Medications. Where other psychopharmacology textbooks—and, indeed, most internships and residencies in psychiatry—lack a solid basis in primary care medicine, this guide bridges that educational gap, offering a thorough examination of all the effects of taking a psychotropic drug as well practical clinical advice on how to manage complications that arise. The book is divided into three parts: The first deals with global issues that affect the assessment and formulation of possible adverse effects, as well as with pertinent concepts related to basic pharmacology, physiology, and medical monitoring. The second part presents information organized by individual organ systems or specific medical circumstances. The final part focuses on summary recommendations covering all the material presented in the book and is followed by helpful appendixes and self-assessment questions and resources for practitioners. This new edition includes: • Updated summaries about what psychiatrists should know regarding drug-drug interactions, iatrogenic cardiac arrhythmias, drug pressor effects and orthostatic hypotension, and drug rashes; as well as updated discussions on avoiding lithium nephrotoxicity, handling adverse effect emergencies, and understanding new FDA classifications about drug safety during pregnancy• An expanded discussion on the strengths and limitations of pharmacogenetic testing to predict adverse drug effects, as well as information about new treatments for sexual dysfunction, sleep disturbances, cognitive complaints, and other maladies• Revised summary tables to aid rapid assessment and management• An expanded section on supplemental resources• An updated and expanded self-assessment section with more key questions Busy clinicians will find in Managing the Side Effects of Psychotropic Medications an accessible reference that provides both scientific and scholarly discussion of the consequences of drug therapies they may prescribe (or avoid), the range of available strategies to effectively manage adverse effects, and the scientific and practical implications of their treatment decisions.

Mental health professionals routinely make treatment decisions without necessarily having an overarching perspective about optimal next steps. This important new book provides them with reader-friendly, pragmatic strategies to approach clinical problems as testable hypotheses. It discusses how to apply concepts based on decision analytic theory using risk-benefit analyses, contingency planning, measurement-based care, shared decision making, pharmacogenetics, disease staging, and machine learning. Readers will learn how these tools can help them craft optimal pharmacological and psychosocial interventions tailored to the needs of an individual patient. The book covers topics such as diagnostic ambiguity, interview technique, applying statistical concepts to individual patients, artificial intelligence, and managing high-risk, treatment-resistant, or demanding and difficult patients. Valuable clinical vignettes are featured throughout the book to illustrate common dilemmas and scenarios where the relative merits of competing treatment options invite a more iterative than definitive approach. For all healthcare professionals who prescribe psychotropic medications.

Despite the lack of guidance available for practitioners, extensive polypharmacy has become the primary method of treating patients with severe and chronic mood, anxiety, psychotic or behavioral disorders. This ground-breaking new book provides an overview of psychopharmacology knowledge and decision-making strategies, integrating findings from evidence-based trials with real-world clinical presentations. It adopts the approach and mind-set of a clinical investigator and reveals how prescribers can practice 'bespoke psychopharmacology', tailoring care to the individualized needs of patients. Practitioners at all levels of expertise will enhance their ability to devise rationale-based treatments, targeting manifestations of dysfunctional neural circuitry and dimensions of psychopathology that cut across conventional psychiatric diagnoses. Presented in a user-friendly, practical, full-colour layout and incorporating summary tables, bullet points, and illustrative case vignettes, it is an invaluable guide for all healthcare professionals prescribing psychotropic medications, including psychiatry specialists, primary care physicians, and advanced practice registered nurses.