Nicola Moccaldi

This book presents a complete overview of the main EEG-based Brain-Computer Interface (BCI) paradigms and the related practical solutions for their design, prototyping, and testing. Readers will explore active, reactive, and passive BCI paradigms, with an emphasis on the operation for developing solutions, addressing the need for customization.Readers will familiarize themselves with the main steps for the realization of low-cost wearable BCIs which include: identification of the most suitable neuro signals for a specific application; definition of the hardware, firmware, and software, with a focus on wearable, non-invasive, and low-cost solutions; development of algorithms for data processing and classification; and, lastly, experimental campaigns for the validation of the prototyped solutions. BCI systems based on electroencephalography (EEG) are investigated and a complete overview of all BCI paradigms is offered. The aim of this book is to drive the reader, from the beginning to the end, along a research-and-development process of a working BCI prototype.This book is a guide for designers, biomedical engineers, students, biotechnologists, and those in the biomedical instrumentation field that would like to conceive, design, prototype, and test an innovative low-cost wearable EEG-based BCI.

The book presents an innovative technology based on injection of a very weak current to trace the quantity of a drug carried immediately after the administration. The book makes the reader familiar with the technology, from the conception through the design of the instrument, up to the preliminary clinical applications. In the first chapter, the method of transdermal drug delivery and the use of impedance spectroscopy in the dermatological field are presented. The second chapter describes a screening measurement campaign aimed at proving the feasibility of the assessment method and identifying the bandwidth of interest. The prototyping, validation and characterization of an instrument to measure the amount of drug delivered (DUSM: Drug Under Skin Meter) are presented in chapter three. In the fourth chapter three experimental campaigns, based on the electrical analysis of the biological tissue behavior due to the drug delivery, are reported: (i) laboratory emulation on eggplants, (ii) ex-vivo tests on pig ears, and finally (iii) in-vivo tests on human volunteers. In the fifth chapter a behavioral model, based on Finite Elements and Partial Differential Equation, of an impedance-based measurement system for assessing the drug released under the skin, during transdermal delivering, is proposed. The last chapter is dedicated to present a campaign in order to prove the suitability for insulin therapy applications. This book is intended for biomedical engineers, biomedical engineering students, operators working in the field of biomedical instrumentation, biotechnologists, and technicians of transdermal vehiculation.

This book presents a complete overview of the main EEG-based Brain-Computer Interface (BCI) paradigms and the related practical solutions for their design, prototyping, and testing. Readers will explore active, reactive, and passive BCI paradigms, with an emphasis on the operation for developing solutions, addressing the need for customization.Readers will familiarize themselves with the main steps for the realization of low-cost wearable BCIs which include: identification of the most suitable neuro signals for a specific application; definition of the hardware, firmware, and software, with a focus on wearable, non-invasive, and low-cost solutions; development of algorithms for data processing and classification; and, lastly, experimental campaigns for the validation of the prototyped solutions. BCI systems based on electroencephalography (EEG) are investigated and a complete overview of all BCI paradigms is offered. The aim of this book is to drive the reader, from the beginning to the end, along a research-and-development process of a working BCI prototype.This book is a guide for designers, biomedical engineers, students, biotechnologists, and those in the biomedical instrumentation field that would like to conceive, design, prototype, and test an innovative low-cost wearable EEG-based BCI.

The book presents an innovative technology based on injection of a very weak current to trace the quantity of a drug carried immediately after the administration. The book makes the reader familiar with the technology, from the conception through the design of the instrument, up to the preliminary clinical applications. In the first chapter, the method of transdermal drug delivery and the use of impedance spectroscopy in the dermatological field are presented. The second chapter describes a screening measurement campaign aimed at proving the feasibility of the assessment method and identifying the bandwidth of interest. The prototyping, validation and characterization of an instrument to measure the amount of drug delivered (DUSM: Drug Under Skin Meter) are presented in chapter three. In the fourth chapter three experimental campaigns, based on the electrical analysis of the biological tissue behavior due to the drug delivery, are reported: (i) laboratory emulation on eggplants, (ii) ex-vivo tests on pig ears, and finally (iii) in-vivo tests on human volunteers. In the fifth chapter a behavioral model, based on Finite Elements and Partial Differential Equation, of an impedance-based measurement system for assessing the drug released under the skin, during transdermal delivering, is proposed. The last chapter is dedicated to present a campaign in order to prove the suitability for insulin therapy applications. This book is intended for biomedical engineers, biomedical engineering students, operators working in the field of biomedical instrumentation, biotechnologists, and technicians of transdermal vehiculation.