Piush Khare

Objective of the present investigation was to formulate and develop hollow microspheres of Losartan potassium.It also referred to as high blood pressure, under a condition in which the arteries have persistently elevated blood pressure but also maintain the therapeutic effect for longer period of time.It was belongs to the class III of BCS exhibiting high solubility and low permeability. Hence, enhanced gastric retention time of drug to controlled release dosage form will increase its absorption.The microballoons can act as potential tool in the form of novel drug delivery system against hypertension.

Oral drug delivery has been an important part of drug delivery and was often linked with tablets, capsules, syrups etc during the discussion about delivery through gastrointestinal tract. Advancements in pharmaceutical sciences and enormous research in the field of drug delivery has laid newer concepts leading to the advent of advanced dosage forms with modified release leading to enhanced therapeutic efficacy. Similarly oral drug delivery has witnessed a change. The book as it is in present form is compilation of theories postulated with regards to oral drug delivery and data related to research work. Different facets of oral drug delivery from conventional to novel have been described through self explicit figures and relevant examples. Underlying basic concepts of different processes have been explained for better understanding of the subject. This book will serve as ready reference for undergraduate and postgraduate students and will cater to the scientific need of those interested in research in oral drug delivery.