Serge Gauthier

Alzheimer's disease is a looming presence in the daily lives of millions, and in our national healthcare discussion. With an aging population, the number of cases of Alzheimer's is reaching epidemic proportions, according to the World Health Organization, and we all -- families, sufferers, and healthcare professionals -- need to develop a response that is clear, well documented, credible, and supported by the latest research. Abundantly illustrated, this complete, essential guide is a reference work intended for all: parents and children, those close to sufferers, and all others who simply wish to inform themselves. It addresses all aspects of the disease: the history of diagnoses, current and future lines of research, family and legal concerns, the first doctor's visit, clinical evaluations, medications, and more. Finally, it clearly presents the real progress that has been made over the past five years in treating and preventing the disease.

Alzheimer disease (AD) has become the most common form of dementia in industrialized countries and represents an increasing burden at the economic, social and medical level. In discussing both the biological aspects of AD as well as the cognitive functions involved, Alzheimer Disease - Neuropsychology and Pharmacology presents a comprehensive picture of the pathology and approaches to diagnosis and treatment. Basic research including animal models, molecular and genetic aspects is also taken into consideration. In part I, the biological correlates of AD are discussed. In part II the neuropsychological aspects such as cognitive impairment, loss of functional autonomy and emergence of neuropsychiatric disturbances of AD are outlined. In part III, strategies for effective treatment and prevention of AD are discussed. This book will be a useful source of information for clinicians as well as researchers in the area of neuropharmacology.

The second edition of Management of Dementia combines a balanced review of the latest knowledge and research in this area with practical guidance based on the authors' considerable personal experience in dementia care. Topics include: The diagnostic criteria of Parkinson’s disease dementia Approaches to combat behavioural disturbances, depression, psychosis, and agitation Suggestions for overcoming sleep disturbances An update on the many genetic findings in Alzheimer’s disease, frontotemporal dementia, and dementia with Lewy bodies Biological markers of Parkinson’s disease dementia Symptomatic and disease-modifying treatments, including drugs and other potential preventive or stabilizing methods Advice for managing the difficult later stages of dementia in long-term care New assessment scales Management of dementia using primary and secondary prevention Drug treatments for patients with specific causes of dementia Treatments based on an individual’s phenotypic and genetic features Directed at practitioners who want to practice evidence-based medicine without losing sight of the patient, this volumr is designed to ensure physicians are dispensing the most appropriate pharmacology while also using other non-pharmacological treatments to their optimum effect. Concise and easy to read, the book provides readers with a full knowledge of the evolution of modern dementia care as well as the basis for understanding new developments as they occur.

Given the increased attention by clinicians, researchers and the pharmaceutical industry to the management and treatment of dementia not only in the elderly but also in increasingly younger populations, the demands for effective evidence-based pharmaceutical control of dementia and quantitative assessment of outcomes have increased. Since some first steps in the early 1960's to the controversial landmark paper of Summers and colleagues, to the most recent trials, it is clear both that much progress has been made, and that much remains to be done. This book is written to take stock of what is now usefully known, and to speculate on directions for the future. Short Contents

Alzheimer disease (AD) has become the most common form of dementia in industrialized countries and represents an increasing burden at the economic, social and medical level. In discussing both the biological aspects of AD as well as the cognitive functions involved, Alzheimer Disease - Neuropsychology and Pharmacology presents a comprehensive picture of the pathology and approaches to diagnosis and treatment. Basic research including animal models, molecular and genetic aspects is also taken into consideration. In part I, the biological correlates of AD are discussed. In part II the neuropsychological aspects such as cognitive impairment, loss of functional autonomy and emergence of neuropsychiatric disturbances of AD are outlined. In part III, strategies for effective treatment and prevention of AD are discussed. This book will be a useful source of information for clinicians as well as researchers in the area of neuropharmacology.