Sidney D. Kirkpatrick

UPDATED AND REVISED EDITION: Throughout his distinguished legal career, Stephen Sheller has relished the role of the underdog, evincing a sharply honed sense of fair play and justice.Early in his career, he represented Black Panthers in Philadelphia when they were arrested on trumped up murder and conspiracy charges. Later, he was in the vanguard of lawyers who took on the tobacco industry in the 1990s and he reprised that strategy a few years later in targeting Big Pharma for its harmful products and their deleterious effects on public health.In Big Pharma, Big Greed The inside story of one lawyer's battle to stem the flood of dangerous medicines and protect public health Sheller tells a tale that is at once deeply personal but also with wide repercussions for the U.S. health care system and the hundreds of millions of Americans whose lives literally depend on it.Decades of litigating against the pharmaceutical industry taught Sheller one irreducible lesson: In too many instances, unneeded and at times dangerous drugs are foisted on the public without adequate warning as to risks, all in the service of boosting industry profits. All too often, achieving block buster status for a patent protected medication becomes an end in itself, as Big Pharma companies manipulate clinical trial data, draft scholarly articles for friendly physicians often in their pay, and market their drugs for uses that never had been approved by the federal Food and Drug Administration.This last practice proved to be something of an Achilles Heel for the industry. In litigation that resulted in settlement and fines in the billions, companies such as Eli Lilly acknowledged marketing drugs off label to a broad range of patients for whom the medications had never been approved. Sheller's litigation formed the basis for these settlements and the effort is ongoing. He and other plaintiffs' lawyers now are suing Janssen Pharmaceuticals for the adverse impacts of its drug, Risperdal, a second generation anti-psychotic that Sheller and others allege is linked to the growth of female breast tissue in young boys and men. Already there have been several big jury verdicts against Janssen with hundreds of more cases yet to be tried.In the book, Sheller not only recounts his major litigation battles but also makes sweeping proposals for industry reform. To restore regulatory credibility, Sheller proposes that responsibility for testing new medicines be taken away from the industry and given over to hospitals and other public entities partnering with government regulators. Pharmaceutical companies that betray the public trust would risk government- initiated dissolution. Harsh medicine to be sure, but Sheller believes entirely appropriate to the underlying malady.

Throughout his distinguished legal career, Stephen Sheller has relished the role of the underdog, evincing a sharply honed sense of fair play and justice.Early in his career, he represented Black Panthers in Philadelphia when they were arrested on trumped up murder and conspiracy charges. Later, he was in the vanguard of lawyers who took on the tobacco industry in the 1990s and he reprised that strategy a few years later in targeting Big Pharma for its harmful products and their deleterious effects on public health.In Big Pharma, Big Greed The inside story of one lawyer's battle to stem the flood of dangerous medicines and protect public health Sheller tells a tale that is at once deeply personal but also with wide repercussions for the U.S. health care system and the hundreds of millions of Americans whose lives literally depend on it.Decades of litigating against the pharmaceutical industry taught Sheller one irreducible lesson: In too many instances, unneeded and at times dangerous drugs are foisted on the public without adequate warning as to risks, all in the service of boosting industry profits. All too often, achieving block buster status for a patent protected medication becomes an end in itself, as Big Pharma companies manipulate clinical trial data, draft scholarly articles for friendly physicians often in their pay, and market their drugs for uses that never had been approved by the federal Food and Drug Administration.This last practice proved to be something of an Achilles Heel for the industry. In litigation that resulted in settlement and fines in the billions, companies such as Eli Lilly acknowledged marketing drugs off label to a broad range of patients for whom the medications had never been approved. Sheller's litigation formed the basis for these settlements and the effort is ongoing. He and other plaintiffs' lawyers now are suing Janssen Pharmaceuticals for the adverse impacts of its drug, Risperdal, a second generation anti-psychotic that Sheller and others allege is linked to the growth of female breast tissue in young boys and men. Already there have been several big jury verdicts against Janssen with hundreds of more cases yet to be tried.In the book, Sheller not only recounts his major litigation battles but also makes sweeping proposals for industry reform. To restore regulatory credibility, Sheller proposes that responsibility for testing new medicines be taken away from the industry and given over to hospitals and other public entities partnering with government regulators. Pharmaceutical companies that betray the public trust would risk government- initiated dissolution. Harsh medicine to be sure, but Sheller believes entirely appropriate to the underlying malady.

On February 1, 1922, the distinguished silent-film director William Desmond Taylor was shot to death in his Los Angeles bungalow by an unknown assailant. Reports of strange activities at the scene of the crime circulated soon after. When the police arrived, was the head of Paramount Studios burning a bundle of papers in the fireplace, and was a well-known actress searching the house for letters she claimed were hers? Despite a full-scale investigation, the case was never solved; for sixty years is has remained a lingering Hollywood scandal. In 1967, more than forty years after Taylor's death, the great King Vidor, whose directing credits include Northwest Passage, The Fountainhead, Duel in the Sun, and War and Peace, determined to solve the mystery, which had haunted him throughout his career, in order to make a film about it. Through his intimate knowledge of both the studios and the stars, he succeeded, where dozens of professional detectives had failed, in discovering the identity of the murderer. But because his findings were so explosive, he decided he could never go public and locked his evidence away. After Vidor's death in 1982, Sidney D. Kirkpatrick, Vidor's authorized biographer, gained access to the evidence and reconstructed the amazing story of Taylor's murder and Vidor's investigation. With a cast of suspects that includes the actress Mabel Normand, a reputed drug addict; the beautiful ing nue, Mary Miles Minter; Mary's domineering mother, Charlotte Shelby; Taylor's homosexual houseman; and Taylor's secretary, who bore an uncanny resemblance to Taylor's mysteriously elusive brother, this true crime story has all the elements of a classic murder mystery. Covered up for more than half a century, the full story can now be told in all its riveting, shocking detail.

With unprecedented access to Edgar Cayce's private letters and trance readings, Sidney Kirkpatrick delivers the definitive biography of the renowned psychic, religious seeker, and father of alternative medicine. Born in rural Kentucky in 1877, Edgar Cayce became known as "the sleeping prophet," and went on to lead an extraordinary life, helping and healing thousands. This is Cayce's fascinating story as it's never been told before.