Thomas C. G. Bosch

Wir sind viele und haben mindestens ebenso viele Bakterienzellen wie eigene Zellen in unserem Körper. Was weiß man über die Funktion, die die Mikroben für Mensch und Tier hat? Thomas Bosch, Evolutions- und Entwicklungsbiologe und Experte auf dem Gebiet der Mikrobiomforschung, blickt bei dieser Frage auf die Fülle an Forschungsergebnissen und auch auf seine eigene Forschung zurück. Wir werden dazu angeregt, beim Nachdenken über die ansteigende Zahl an „Lifestyle“ Erkrankungen in einem ganzheitlichen Ansatz die Bedeutung des Mikrobioms zu berücksichtigen. Wir sind viele und wir waren schon immer viele, auch in der Evolutionsgeschichte. Ohne Mikroben können wir uns nicht normal entwickeln und sind krank. Wie wir leben und uns ernähren hat starken Einfluss auf die Mikroorganismen. Hinter dieser Erkenntnis steckt auch die Perspektive, durch Eingriffe in das Mikrobiom unsere Gesundheit zu erhalten. Die Komplexität der Mikrobiomforschung kann als kompakte Erzählung schwer zu verdauen sein. Dieses Buch kann es.

This book examines how the growing knowledge of the huge range of animal-bacterial interactions, whether in shared ecosystems or intimate symbioses, is fundamentally altering our understanding of animal biology. Individuals from simple invertebrates to human are not solitary, homogenous entities but consist of complex communities of many species that likely evolved during a billion years of coexistence. Defining the individual microbe-host conversations in these consortia, is a challenging but necessary step on the path to understanding the function of the associations as a whole. The hologenome theory of evolution considers the holobiont with its hologenome as a unit of selection in evolution. This new view may have profound impact on understanding a strictly microbe/symbiont-dependent life style and its evolutionary consequences. It may also affect the way how we approach complex environmental diseases from corals (coral bleaching) to human (inflammatory bowel disease etc). The book is written for scientists as well as medically interested persons in the field of immunobiology, microbiology, evolutionary biology, evolutionary medicine and corals.

This book examines how the growing knowledge of the huge range of animal-bacterial interactions, whether in shared ecosystems or intimate symbioses, is fundamentally altering our understanding of animal biology. Individuals from simple invertebrates to human are not solitary, homogenous entities but consist of complex communities of many species that likely evolved during a billion years of coexistence. Defining the individual microbe-host conversations in these consortia, is a challenging but necessary step on the path to understanding the function of the associations as a whole. The hologenome theory of evolution considers the holobiont with its hologenome as a unit of selection in evolution. This new view may have profound impact on understanding a strictly microbe/symbiont-dependent life style and its evolutionary consequences. It may also affect the way how we approach complex environmental diseases from corals (coral bleaching) to human (inflammatory bowel disease etc). The book is written for scientists as well as medically interested persons in the field of immunobiology, microbiology, evolutionary biology, evolutionary medicine and corals.