Thomas Lemke

Maintaining its status as the gold standard in medicinal chemistry education, Foye's Principles of Medicinal Chemistry, 9th Edition, presents a renewed focus on the fundamental concepts that form the backbone of this critical discipline. This latest edition, helmed by new senior editors Marc Harrold and Kim Beck, continues the text's legacy of excellence while streamlining content for today's pharmacy students and practitioners. Expert contributions from experienced educators, research scientists, and clinicians clarify the chemical basis of drug action, emphasizing the structure-activity relationships, physicochemical-pharmacokinetic properties, and metabolic profiles of the most commonly used drugs. UPDATED! Focused content emphasizes essential information in an ideal format for contemporary PharmD curricula. UPDATED! Drug information equips students with the latest developments in drug discovery, structure optimization and clinical use. Clinical Significance testimonials provide a clinician’s view of the relevance of medicinal chemistry to practice. End-of-Chapter exercises provide valuable self-assessment opportunities and reinforce key concepts.

Examines the theoretical achievements and the political impact of the new materialisms Materialism, a rich philosophical tradition that goes back to antiquity, is currently undergoing a renaissance. In The Government of Things, Thomas Lemke provides a comprehensive overview and critical assessment of this "new materialism". In analyzing the work of Graham Harman, Jane Bennett, and Karen Barad, Lemke articulates what, exactly, new materialism is and how it has evolved. These insights open up new spaces for critical thought and political experimentation, overcoming the limits of anthropocentrism. Drawing on Michel Foucault's concept of a "government of things", the book also goes beyond new materialist scholarship which tends to displace political questions by ethical and aesthetic concerns. It puts forward a relational and performative account of materialities that more closely attends to the interplay of epistemological, ontological, and political issues. Lemke provides definitive and much-needed clarity about the fascinating potential—and limitations—of new materialism as a whole. The Government of Things revisits Foucault's more-than-human understanding of government to capture a new constellation of power: "environmentality". As the book demonstrates, contemporary modes of government seek to control the social, ecological, and technological conditions of life rather than directly targeting individuals and populations. The book offers an essential and much needed tool to critically examine this political shift.

Examines the theoretical achievements and the political impact of the new materialisms Materialism, a rich philosophical tradition that goes back to antiquity, is currently undergoing a renaissance. In The Government of Things, Thomas Lemke provides a comprehensive overview and critical assessment of this "new materialism". In analyzing the work of Graham Harman, Jane Bennett, and Karen Barad, Lemke articulates what, exactly, new materialism is and how it has evolved. These insights open up new spaces for critical thought and political experimentation, overcoming the limits of anthropocentrism. Drawing on Michel Foucault's concept of a "government of things", the book also goes beyond new materialist scholarship which tends to displace political questions by ethical and aesthetic concerns. It puts forward a relational and performative account of materialities that more closely attends to the interplay of epistemological, ontological, and political issues. Lemke provides definitive and much-needed clarity about the fascinating potential—and limitations—of new materialism as a whole. The Government of Things revisits Foucault's more-than-human understanding of government to capture a new constellation of power: "environmentality". As the book demonstrates, contemporary modes of government seek to control the social, ecological, and technological conditions of life rather than directly targeting individuals and populations. The book offers an essential and much needed tool to critically examine this political shift.

With expert contributions from experienced educators, research scientists and clinicians, Foye’s Principles of Medicinal Chemistry, Eighth Edition is an invaluable resource for professional students, graduate students and pharmacy faculty alike.? This ‘gold standard’ text explains the chemical basis of drug action, emphasizing the structure-activity relationships, physicochemical-pharmacokinetic properties, and metabolic profiles of the most commonly used drugs. Comprehensive coverage of the most cutting edge understanding of drug chemistry, organized and written for ready comprehensionExtensively referenced to allow learners to explore areas of interest in greater depthContemporary focus on drugs viewed by practitioners as the most clinically important in today’s health care environmentClinical Significance testimonials that provide a clinician’s view of the relevance of medicinal chemistry to practiceScience-practice interface made explicit through drug monographs that highlight therapeutic indications, adverse reactions and drug-drug interactionsEnd-of-Chapter exercises that allow learners to test their understanding and recall of key conceptseBook available . Fast, smart, and convenient, today’s eBooks can transform learning. These interactive, fully searchable tools offer 24/7 access on multiple devices, the ability to highlight and share notes, and much more

Lemke offers the most comprehensive and systematic account of Michel Foucault's work on power and government from 1970 until his death in 1984. He convincingly argues, using material that has only partly been translated into English, that Foucault's concern with ethics and forms of subjectivation is always already integrated into his political concerns and his analytics of power. The book also shows how the concept of government was taken up in different lines of research in France before it gave rise to "governmentality studies" in the Anglophone world.A Critique of Political Reason: Foucault's Analysis of Modern Governmentality provides a clear and well-structured exposition that is theoretically challenging but also accessible for a wider audience. Thus, the book can be read both as an original examination of Foucault's concept of government and as a general introduction to his "genealogy of power".

Tracking the development of Foucault's key conceptsLemke offers the most comprehensive and systematic account of Michel Foucault's work on power and government from 1970 until his death in 1984. He convincingly argues, using material that has only partly been translated into English, that Foucault's concern with ethics and forms of subjectivation is always already integrated into his political concerns and his analytics of power. The book also shows how the concept of government was taken up in different lines of research in France before it gave rise to "governmentality studies" in the Anglophone world.A Critique of Political Reason: Foucault's Analysis of Modern Governmentality provides a clear and well-structured exposition that is theoretically challenging but also accessible for a wider audience. Thus, the book can be read both as an original examination of Foucault's concept of government and as a general introduction to his "genealogy of power."

Die Autoren rekonstruieren den sozialwissenschaftlichen Forschungsstand zu gesellschaftlichen Implikationen der Präimplantationsdiagnostik (PID) und identifizieren u.a. folgende Problemkomplexe: eine Expansion der PID in neue Anwendungsfelder, eine Verfestigung sozialer Ungleichheiten sowie einen Wandel normativer Erwartungen hin zur Vorstellung einer genetischen Reproduktionsverantwortung. Diese konvergiert mit einer individualisierenden Präventionslogik, die gegenwärtige Transformationsprozesse der Medizin und Gesundheitspolitik kennzeichnet.

This book outlines the European framework of family reunification and the reasons for focussing on Austria, Finland and Germany. It presents the case studies that provide a general understanding of how DNA testing affects the national immigration policies.

I de senere år er forståelsen af sundhed undergået en række forandringer. Fokus er blevet udvidet fra patienten som biomedicinsk krop til et subjekt, der oplever sundhedsproblemer og lever med dem i interaktion med det omgivende miljø. Sundhed er blevet et langt mere omfattende anliggende, der potentielt vedrører alle aspekter af vores tilværelse. Det betyder samtidig, at ideer om sundhed ikke kan dikteres af sundhedsmyndigheder og eksperter. Sundhedsfremmende tiltag må i dag tage målgruppens værdier og rationaler i betragtning, bl.a. i form af kampagner, der ikke kræver absolut overholdelse af sundhedsdoktriner, men forsøger at få folk til at afveje deres usunde vaner i forhold til sundhedsværdier. Sundhed og magt tager bestik af denne udvikling. I bogen står Michel Foucaults begreb om biopolitik centralt – et begreb, som netop sætter fokus på, at reguleringen af det biologiske liv sammenvæves med en mere omfattende ledelse af sociale og kulturelle forhold. Bogen rummer bidrag fra førende danske og internationale forskere, som anlægger perspektiver, der udfordrer traditionel sundhedsforskning, herunder genealogi, systemteori, psykoanalyse og aktør-netværk-teori. Den henvender sig til studerende og fagfolk på sundheds- og samfundsvidenskabelige uddannelser. Redigeret af Mads Peter Karlsen og Kaspar Villadsen, hhv. adjunkt og professor mso ved Copenhagen Business School.

Over the past 15 years, a series of empirical studies in different countries have shown that our increasing genetic knowledge leads to new forms of exclusion, disadvantaging and stigmatization. The spectrum of this "genetic discrimination" ranges from disadvantages at work, via problems with insurance policies, to difficulties with adoption agencies. The empirical studies on the problem of genetic discrimination have not gone unnoticed. Since the beginning of the 1990s, a series of legislative initiatives and statements, both on the national level and on the part of international and supranational organizations and commissions, have been put forward as ways of protecting people from genetic discrimination.This is the first book to critically evaluate the empirical evidence and the theoretical usefulness of the concept of "genetic discrimination." It discusses the advantages and limitations of adopting the concept, and offers a more complex account distinguishing between several dimensions and forms of genetic discrimination.

Suspect Families is the first book to investigate the social, political, and ethical implications of parental testing for family reunification in immigration cases. Drawing on policy documents, legal frameworks, case study material and interviews with representatives of governmental and non-governmental organisation and immigration authorities, immigration lawyers, geneticists and applicants for family reunification, the book analyses the different political regimes and social arrangements in which DNA analysis is adopted for decision-making on family reunification in three distinct European countries: Austria, Finland and Germany. Interdisciplinary in scope, the book reconstructs the processes, institutional logic and the political and administrative practices of DNA testing from a comparative perspective, combining theoretical conceptualisation with detailed empirical work to explore the central societal, political and ethical issues raised by the use of DNA profiling in the context of immigration policy. A ground-breaking study of the role played by new technologies in migration decisions, Suspect Families will appeal to scholars of sociology, political science, science and technology studies and surveillance studies.

Over the past 15 years, a series of empirical studies in different countries have shown that our increasing genetic knowledge leads to new forms of exclusion, disadvantaging and stigmatization. The spectrum of this "genetic discrimination" ranges from disadvantages at work, via problems with insurance policies, to difficulties with adoption agencies. The empirical studies on the problem of genetic discrimination have not gone unnoticed. Since the beginning of the 1990s, a series of legislative initiatives and statements, both on the national level and on the part of international and supranational organizations and commissions, have been put forward as ways of protecting people from genetic discrimination.This is the first book to critically evaluate the empirical evidence and the theoretical usefulness of the concept of "genetic discrimination." It discusses the advantages and limitations of adopting the concept, and offers a more complex account distinguishing between several dimensions and forms of genetic discrimination.

Michel Foucault is one of the most cited authors in social science. This book discusses one of his most influential concepts: governmentality. Reconstructing its emergence in Foucault's analytics of power, the book explores the theoretical strengths the concept of governmentality offers for political analysis and critique. It highlights the intimate link between neoliberal rationalities and the problem of biopolitics including issues around genetic and reproductive technologies. This book is a useful introduction to Foucault's work on power and governmentality suitable for experts and students alike

Michel Foucault is one of the most cited authors in social science. This book discusses one of his most influential concepts: governmentality. Reconstructing its emergence in Foucault's analytics of power, the book explores the theoretical strengths the concept of governmentality offers for political analysis and critique. It highlights the intimate link between neoliberal rationalities and the problem of biopolitics including issues around genetic and reproductive technologies. This book is a useful introduction to Foucault's work on power and governmentality suitable for experts and students alike

The first systematic overview of the notion of biopolitics and its relevance in contemporary theoretical debate The biological features of human beings are now measured, observed, and understood in ways never before thought possible, defining norms, establishing standards, and determining average values of human life. While the notion of "biopolitics" has been linked to everything from rational decision-making and the democratic organization of social life to eugenics and racism, Thomas Lemke offers the very first systematic overview of the history of the notion of biopolitics, exploring its relevance in contemporary theoretical debates and providing a much needed primer on the topic. Lemke explains that life has become an independent, objective and measurable factor as well as a collective reality that can be separated from concrete living beings and the singularity of individual experience. He shows how our understanding of the processes of life, the organizing of populations and the need to "govern" individuals and collectives lead to practices of correction, exclusion, normalization, and disciplining. In this lucidly written book, Lemke outlines the stakes and the debates surrounding biopolitics, providing a systematic overview of the history of the notion and making clear its relevance for sociological and contemporary theoretical debates.

The first systematic overview of the notion of biopolitics and its relevance in contemporary theoretical debate The biological features of human beings are now measured, observed, and understood in ways never before thought possible, defining norms, establishing standards, and determining average values of human life. While the notion of "biopolitics" has been linked to everything from rational decision-making and the democratic organization of social life to eugenics and racism, Thomas Lemke offers the very first systematic overview of the history of the notion of biopolitics, exploring its relevance in contemporary theoretical debates and providing a much needed primer on the topic. Lemke explains that life has become an independent, objective and measurable factor as well as a collective reality that can be separated from concrete living beings and the singularity of individual experience. He shows how our understanding of the processes of life, the organizing of populations and the need to "govern" individuals and collectives lead to practices of correction, exclusion, normalization, and disciplining. In this lucidly written book, Lemke outlines the stakes and the debates surrounding biopolitics, providing a systematic overview of the history of the notion and making clear its relevance for sociological and contemporary theoretical debates.

Die Analyse der Gouvernementalität von Foucault weist auf den inneren Zusammenhang zwischen der "Genealogie des modernen Staates" und der "Genealogie des modernen Subjekts" hin. Damit gelingt es, die Beziehung zwischen "Bio-Politik" und Rassismus, Freiheit und Sicherheit, dem Abbau sozialstaatlicher Leistungen und dem Appell an Eigenverantwortung und Selbstsorge aufzuzeigen. Der Neoliberalismus ist somit eine politische Rationalität, die nicht nur eine neue Form des Sozialen erfindet, sondern auch eine neue Subjektivität. In ihr sind wirtschaftlicher Wohlstand und persönliches Wohlsein gekoppelt, wobei nicht nur der individuelle Körper, sondern auch der Staat als politischer Körper schlank und fit sein muss. Lemkes Studie beruht auf bislang unbekanntem Archivmaterial und bietet eine wichtige Neuinterpretation Foucaults, die umfassendste Bibliographie seiner politisch und sozialwissenschaftlich relevanten Arbeiten und wird selbst zum Werkzeug für eine "Kritik der politischen Vernunft".

»Vergesst Foucault!« – so lautete die provokante Aufforderung Jean Baudrillards Ende der 1970er Jahre. Ein Vierteljahrhundert später ist die sozialwissenschaftliche Auseinandersetzung mit dem Werk des französischen Historikers und Philosophen intensiver denn je. Zwei Konzepte haben in den vergangenen Jahren die Rezeption in besonderer Weise geprägt: Gouvernementalität und Biopolitik. Der Band erkundet die gegenwartsdiagnostische Reichweite und die soziologische Relevanz der beiden Konzepte. Er zeichnet ihre Entstehungskontexte und Bedeutungsdimensionen nach und diskutiert Perspektiven und Probleme der aktuellen Rezeption. Das Ergebnis ist eine theoretische Weiterentwicklung der Machtanalytik, die sie auf empirische Forschungsfragen bezieht und ihr gesellschaftskritisches Potenzial aufzeigt.