Yang Zhang

Introduction to Structural Bioinformatics offers a complete overview to the fundamental concepts and methodologies of structural bioinformatics and computational structural biology. The book is divided into three sections, beginning with a discussion of the key principles of bioinformatics and fundamental aspects including bioinformatics databases, multiple sequence alignment and machine learning. Section two then moves on to structural bioinformatics, where topics include Monte Carlo simulation, protein structure prediction, RNA structure prediction, and protein design. The final section of the book focuses on experimental structural determination, where chapters focus on techniques including X-ray crystallography, nuclear magnetic resonance and cryo-electron microscopy. This is an ideal guide to the key principles, methods and most up-to-date developments across structural bioinformatics and computational structural biology, providing a comprehensive reference for postgraduate students, instructors and researchers working in these and adjacent subjects.

Given the rise of AI and the advent of online collaboration opportunities (e.g., social media, crowdsourcing), emerging research has started to investigate the integration of AI and human intelligence, especially in a collaborative social context. This creates unprecedented challenges and opportunities in the field of Social Intelligence (SI), where the goal is to explore the collective intelligence of both humans and machines by understanding their complementary strengths and interactions in the social space. In this book, a set of novel human-centered AI techniques are presented to address the challenges of social intelligence applications, including multimodal approaches, robust and generalizable frameworks, and socially empowered explainable AI designs. The book then presents several human-AI collaborative learning frameworks that jointly integrate the strengths of crowd wisdom and AI to address the limitations inherent in standalone solutions. The book also emphasizes pressing societal issues in the realm of social intelligence, such as fairness, bias, and privacy. Real-world case studies from different applications in social intelligence are presented to demonstrate the effectiveness of the proposed solutions in achieving substantial performance gains in various aspects, such as prediction accuracy, model generalizability and explainability, algorithmic fairness, and system robustness.

Die Forschungsfrage des vorliegenden Buches bewegt sich im Bereich der personenbezogenen Politikforschung: Die Beziehung zwischen Angela Merkels Persönlichkeitsgrundzügen und der deutschen Außenpolitik steht im Mittelpunkt der Analysen. Der Autor deutet und interpretiert die Auswirkungen auf die deutsche Außenpolitik anhand der Beispiele Euro-, Ukraine- und Flüchtlingskrise sowie die China-Politik. Er erarbeitet vier Kategorien, denen ihre Persönlichkeitsmerkmale zugeordnet werden können. Die Analyse konzentriert sich vornehmlich auf Merkels Reaktionen auf die externen Faktoren und ihre Optionen bei der Entscheidungsfindung. Die Ergebnisse zeigen, dass Angela Merkels Persönlichkeitsmerkmale erhebliche Auswirkungen auf den Verlauf dieser bedeutenden außenpolitischen Ereignisse zeigten.

This thesis presents pioneering experimental and numerical studies on three aspects of the combustion characteristics of lean premixed syngas/air flames, namely the laminar flame speed, extinction limit and flammability limit. It illustrates a new extinction exponent concept, which enriches the combustion theory. Above all, the book provides the following: a) a series of carefully measured data and theoretical analyses to reveal the intrinsic mechanisms of the fuel composition effect on the propagation and extinction of lean syngas/air flames; b) a mixing model and correlation to predict the laminar flame speed of multi-component syngas fuels, intended for engineering computations; c) a new “extinction exponent” concept to describe the critical effects of chemical kinetics on the extinction of lean premixed syngas/air flames; and d) the effects and mechanism of the dilution of incombustible components on lean premixed syngas/air flames and the preferential importance among the thermal, chemical and diffusion effects.

In IoT scenarios, ways in which large-scale and cross-domain service systems can be established are still unclear, and no systematic or in-depth theories and methods have yet been found. An effective, formal foundation to IoT application designs could serve as a knowledge base for a variety of virtual world applications. Integrating and Streamlining Event-Driven IoT Services discusses how to observe isolated services running by different observation sources, how to fuse different observations to deal with observation conflict and incompleteness, and how to deal with adversaries and physical system features for real-time property enforcement over the fused knowledge. Overall, presenting an exploration of systematic theories and methods for the design of IoT services based on the principles of streamlining and integration, this book features research on topics such as CEP service, virtual machine technologies, and hybrid EPC. It is ideally designed for engineers, researchers, and university students seeking coverage on applications for smart cities, smart grids, and Industry 4.0.

In IoT scenarios, ways in which large-scale and cross-domain service systems can be established are still unclear, and no systematic or in-depth theories and methods have yet been found. An effective, formal foundation to IoT application designs could serve as a knowledge base for a variety of virtual world applications.Integrating and Streamlining Event-Driven IoT Services discusses how to observe isolated services running by different observation sources, how to fuse different observations to deal with observation conflict and incompleteness, and how to deal with adversaries and physical system features for real-time property enforcement over the fused knowledge. Overall, presenting an exploration of systematic theories and methods for the design of IoT services based on the principles of streamlining and integration, this book features research on topics such as CEP service, virtual machine technologies, and hybrid EPC. It is ideally designed for engineers, researchers, and university students seeking coverage on applications for smart cities, smart grids, and Industry 4.0.

This monograph covers the theory of finite and infinite matrices over the fields of real numbers, complex numbers and over quaternions. Emphasizing topics such as sections or truncations and their relationship to the linear operator theory on certain specific separable and sequence spaces, the authors explore techniques like conformal mapping, iterations and truncations that are used to derive precise estimates in some cases and explicit lower and upper bounds for solutions in the other cases.Most of the matrices considered in this monograph have typically special structures like being diagonally dominated or tridiagonal, possess certain sign distributions and are frequently nonsingular. Such matrices arise, for instance, from solution methods for elliptic partial differential equations. The authors focus on both theoretical and computational aspects concerning infinite linear algebraic equations, differential systems and infinite linear programming, among others. Additionally, the authors cover topics such as Bessel’s and Mathieu’s equations, viscous fluid flow in doubly connected regions, digital circuit dynamics and eigenvalues of the Laplacian.

This thesis presents pioneering experimental and numerical studies on three aspects of the combustion characteristics of lean premixed syngas/air flames, namely the laminar flame speed, extinction limit and flammability limit. It illustrates a new extinction exponent concept, which enriches the combustion theory. Above all, the book provides the following: a) a series of carefully measured data and theoretical analyses to reveal the intrinsic mechanisms of the fuel composition effect on the propagation and extinction of lean syngas/air flames; b) a mixing model and correlation to predict the laminar flame speed of multi-component syngas fuels, intended for engineering computations; c) a new “extinction exponent” concept to describe the critical effects of chemical kinetics on the extinction of lean premixed syngas/air flames; and d) the effects and mechanism of the dilution of incombustible components on lean premixed syngas/air flames and the preferential importance among the thermal, chemical and diffusion effects.

This book covers the latest research work done in the area of interface mechanics of collagen and chitin-based biomaterials along with various techniques that can be used to understand mechanics of biological systems and materials. Topics covered include Raman spectroscopy of biological systems, scale dependence of the mechanical properties and microstructure of crustaceans thin films as biomimetic materials, as well as the role of molecular-level modeling. The use of nanomechanics to investigate interface thermomechanics of collagen and chitin-based biomaterials is also covered in detail.This book also:• Details spectroscope experiments as well as nanomechanic experiments• Reviews exhaustively phenomenological models and Raman spectroscopy of biological systems• Covers the latest in multiscaling for molecular models to predict lab-scale sample properties and investigates interface thermomechanics

This monograph covers the theory of finite and infinite matrices over the fields of real numbers, complex numbers and over quaternions. Emphasizing topics such as sections or truncations and their relationship to the linear operator theory on certain specific separable and sequence spaces, the authors explore techniques like conformal mapping, iterations and truncations that are used to derive precise estimates in some cases and explicit lower and upper bounds for solutions in the other cases.Most of the matrices considered in this monograph have typically special structures like being diagonally dominated or tridiagonal, possess certain sign distributions and are frequently nonsingular. Such matrices arise, for instance, from solution methods for elliptic partial differential equations. The authors focus on both theoretical and computational aspects concerning infinite linear algebraic equations, differential systems and infinite linear programming, among others. Additionally, the authors cover topics such as Bessel’s and Mathieu’s equations, viscous fluid flow in doubly connected regions, digital circuit dynamics and eigenvalues of the Laplacian.

This book covers the latest research work done in the area of interface mechanics of collagen and chitin-based biomaterials along with various techniques that can be used to understand mechanics of biological systems and materials. Topics covered include Raman spectroscopy of biological systems, scale dependence of the mechanical properties and microstructure of crustaceans thin films as biomimetic materials, as well as the role of molecular-level modeling. The use of nanomechanics to investigate interface thermomechanics of collagen and chitin-based biomaterials is also covered in detail.This book also:• Details spectroscope experiments as well as nanomechanic experiments• Reviews exhaustively phenomenological models and Raman spectroscopy of biological systems• Covers the latest in multiscaling for molecular models to predict lab-scale sample properties and investigates interface thermomechanics